Autophagy, Volume 15, Issue 8 (2019)

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Autophagy, Volume 15, Issue 8 (2019)

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Research Paper

Article
TP53INP2 contributes to autophagosome formation by promoting LC3-ATG7 interaction
Zhiyuan You, Yinfeng Xu, Wei Wan, Li Zhou, Jin Li, Tianhua Zhou, Yin Shi & Wei Liu
Pages: 1309-1321
Published online: 20 Feb 2019
AbstractforTP53INP2 contributes to autophagosome formation by promoting LC3-ATG7 interaction | Full Text | References | PDF (6.1 MB) | EPUB | Supplemental
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Article
A novel transgenic zebrafish line allows for in vivo quantification of autophagic activity in neurons
Sataree Khuansuwan, Lisa M. Barnhill, Sizhu Cheng & Jeff M. Bronstein
Pages: 1322-1332
Published online: 01 Mar 2019
AbstractforA novel transgenic zebrafish line allows for in vivo quantification of autophagic activity in neurons | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 3384 Views
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Article
Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs
Åsa Birna Birgisdottir, Stephane Mouilleron, Zambarlal Bhujabal, Martina Wirth, Eva Sjøttem, Gry Evjen, Wenxin Zhang, Rebecca Lee, Nicola O’Reilly, Sharon A. Tooze, Trond Lamark & Terje Johansen
Pages: 1333-1355
Published online: 04 Mar 2019
AbstractforMembers of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs | Full Text | References | PDF (9.7 MB) | EPUB | Supplemental
  • 6942 Views
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Open Access

Research Paper - Translational

Article
SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions
Tae Sung Kim, Yeung Bae Jin, Yi Sak Kim, Sup Kim, Jin Kyung Kim, Hye-Mi Lee, Hyun-Woo Suh, Jin Ho Choe, Young Jae Kim, Bon-Sang Koo, Han-Na Kim, Mingyu Jung, Sang-Hee Lee, Don-Kyu Kim, Chaeuk Chung, Ji-Woong Son, Jung-Joon Min, Jin-Man Kim, Chu-Xia Deng, Hyun Seok Kim, Sang-Rae Lee & Eun-Kyeong Jo
Pages: 1356-1375
Published online: 04 Mar 2019
AbstractforSIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions | Full Text | References | PDF (9 MB) | EPUB | Supplemental
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Research Paper

Article
A novel orally available seleno-purine molecule suppresses triple-negative breast cancer cell proliferation and progression to metastasis by inducing cytostatic autophagy
Chia-Hao Chang, Krikor Bijian, Dominik Wernic, Jie Su, Sabrina Daniela da Silva, Henry Yu, Dinghong Qiu, Mariana Asslan & Moulay A. Alaoui-Jamali
Pages: 1376-1390
Published online: 01 Mar 2019
AbstractforA novel orally available seleno-purine molecule suppresses triple-negative breast cancer cell proliferation and progression to metastasis by inducing cytostatic autophagy | Full Text | References | PDF (9.1 MB) | EPUB | Supplemental
  • 3049 Views
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Article
Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy
Madhuri Chaurasia, Swapnil Gupta, Asmita Das, B.S. Dwarakanath, Anne Simonsen & Kulbhushan Sharma
Pages: 1391-1406
Published online: 20 Mar 2019
AbstractforRadiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy | Full Text | References | PDF (7.9 MB) | EPUB | Supplemental
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Article
Gamma secretase orthologs are required for lysosomal activity and autophagic degradation in Dictyostelium discoideum, independent of PSEN (presenilin) proteolytic function
Devdutt Sharma, Grant Otto, Eleanor C. Warren, Philip Beesley, Jason S. King & Robin S. B. Williams
Pages: 1407-1418
Published online: 21 Mar 2019
AbstractforGamma secretase orthologs are required for lysosomal activity and autophagic degradation in Dictyostelium discoideum, independent of PSEN (presenilin) proteolytic function | Full Text | References | PDF (3.8 MB) | EPUB | Supplemental
  • 2522 Views
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Open Access
Article
METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes
Huiwen Song, Xing Feng, Heng Zhang, Yunmei Luo, Juan Huang, Meihua Lin, Junfei Jin, Xue Ding, Shujing Wu, He Huang, Tian Yu, Mukun Zhang, Haiou Hong, Shihua Yao, Yongxiang Zhao & Zhiyong Zhang
Pages: 1419-1437
Published online: 17 Mar 2019
AbstractforMETTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes | Full Text | References | PDF (8.1 MB) | EPUB | Supplemental
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Open Access
Article
The epg5 knockout zebrafish line: a model to study Vici syndrome
Giacomo Meneghetti, Tatjana Skobo, Martina Chrisam, Nicola Facchinello, Camilla Maria Fontana, Stefania Bellesso, Patrizia Sabatelli, Flavia Raggi, Francesco Cecconi, Paolo Bonaldo & Luisa Dalla Valle
Pages: 1438-1454
Published online: 17 Mar 2019
AbstractforThe epg5 knockout zebrafish line: a model to study Vici syndrome | Full Text | References | PDF (7.8 MB) | EPUB | Supplemental
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Letter to the Editor

Lysosomal inhibition attenuates peroxisomal gene transcription via suppression of PPARA and PPARGC1A levels
Hayden Weng Siong Tan, B. Anjum, Han-Ming Shen, Sujoy Ghosh, Paul M. Yen & Rohit A. Sinha
Pages: 1455-1459
Published online: 28 Apr 2019
AbstractforLysosomal inhibition attenuates peroxisomal gene transcription via suppression of PPARA and PPARGC1A levels | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 4767 Views
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Commentary

Article Commentary
Rapamycin and Alzheimer disease: a double-edged sword?
Julian M Carosi & Timothy J Sargeant
Pages: 1460-1462
Published online: 22 May 2019
AbstractforRapamycin and Alzheimer disease: a double-edged sword? | Full Text | References | PDF (656.8 KB) | EPUB
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Autophagic Punctum

Article Commentary
Vault RNA emerges as a regulator of selective autophagy
Rastislav Horos, Magdalena Büscher, Carsten Sachse & Matthias W. Hentze
Pages: 1463-1464
Published online: 03 May 2019
AbstractforVault RNA emerges as a regulator of selective autophagy | Full Text | References | PDF (557.9 KB) | EPUB
  • 1505 Views
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Article Commentary
ATL3, a cargo receptor for reticulophagy
Qingzhou Chen, Junlin Teng & Jianguo Chen
Pages: 1465-1466
Published online: 28 Apr 2019
AbstractforATL3, a cargo receptor for reticulophagy | Full Text | References | PDF (715.6 KB) | EPUB
  • 1420 Views
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Article Commentary
Loss of proteins associated with amyotrophic lateral sclerosis affects lysosomal acidification via different routes
Mümine Şentürk, Dongxue Mao & Hugo J. Bellen
Pages: 1467-1469
Published online: 28 Apr 2019
AbstractforLoss of proteins associated with amyotrophic lateral sclerosis affects lysosomal acidification via different routes | Full Text | References | PDF (871.4 KB) | EPUB
  • 1509 Views
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Article Commentary
The MTORC1-mediated autophagy is regulated by the FBXW7-SHOC2-RPTOR axis
Chuan-Ming Xie & Yi Sun
Pages: 1470-1472
Published online: 03 May 2019
AbstractforThe MTORC1-mediated autophagy is regulated by the FBXW7-SHOC2-RPTOR axis | Full Text | References | PDF (1 MB) | EPUB
  • 1791 Views
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Article Commentary
Noncatalytic functions of IPMK are essential for activation of autophagy and liver regeneration
Prasun Guha & Solomon H Snyder
Pages: 1473-1474
Published online: 21 May 2019
AbstractforNoncatalytic functions of IPMK are essential for activation of autophagy and liver regeneration | Full Text | References | PDF (604.5 KB) | EPUB
  • 1295 Views
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Article Commentary
How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates
Eleonora Turco, Marie Witt, Christine Abert, Tobias Bock-Bierbaum, Ming-Yuan Su, Riccardo Trapannone, Martin Sztacho, Alberto Danieli, Xiaoshan Shi, Gabriele Zaffagnini, Annamaria Gamper, Martina Schuschnig, Dorotea Fracchiolla, Daniel Bernklau, Julia Romanov, Markus Hartl, James H. Hurley, Oliver Daumke & Sascha Martens
Pages: 1475-1477
Published online: 22 May 2019
AbstractforHow RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates | Full Text | PDF (670.8 KB) | EPUB
  • 1863 Views
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Article Commentary
Autophagy regulates steroid production by mediating cholesterol trafficking in endocrine cells
Michael J. Texada, Alina Malita & Kim Rewitz
Pages: 1478-1480
Published online: 23 May 2019
AbstractforAutophagy regulates steroid production by mediating cholesterol trafficking in endocrine cells | Full Text | PDF (819.2 KB) | EPUB
  • 1558 Views
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Article Commentary
Termination of Drosophila mushroom body neurogenesis via autophagy and apoptosis
Sarah E Siegrist
Pages: 1481-1482
Published online: 23 May 2019
CitationforTermination of Drosophila mushroom body neurogenesis via autophagy and apoptosis | Full Text | References | PDF (620.7 KB) | EPUB
  • 948 Views
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Article Commentary
Come and eat: mitochondrial transport guides mitophagy in ischemic neuronal axons
Yanrong Zheng, Xiaoli Wu, Zhong Chen & Xiangnan Zhang
Pages: 1483-1484
Published online: 26 May 2019
AbstractforCome and eat: mitochondrial transport guides mitophagy in ischemic neuronal axons | Full Text | References | PDF (476.6 KB) | EPUB
  • 1682 Views
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Article Commentary
Toward the function of mammalian ATG12–ATG5-ATG16L1 complex in autophagy and related processes
Alf Håkon Lystad, Sven R. Carlsson & Anne Simonsen
Pages: 1485-1486
Published online: 23 May 2019
AbstractforToward the function of mammalian ATG12–ATG5-ATG16L1 complex in autophagy and related processes | Full Text | PDF (639.7 KB) | EPUB
  • 2135 Views
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Article Commentary
DDR1 (discoidin domain receptor tyrosine kinase 1) drives glioblastoma therapy resistance by modulating autophagy
Anne Vehlow & Nils Cordes
Pages: 1487-1488
Published online: 23 May 2019
AbstractforDDR1 (discoidin domain receptor tyrosine kinase 1) drives glioblastoma therapy resistance by modulating autophagy | Full Text | References | PDF (836.1 KB) | EPUB
  • 2427 Views
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Article Commentary
Bacterial outer membrane vesicles trigger pre-activation of a xenophagic response via AMPK
Truc T. Losier & Ryan C. Russell
Pages: 1489-1491
Published online: 23 May 2019
AbstractforBacterial outer membrane vesicles trigger pre-activation of a xenophagic response via AMPK | Full Text | References | PDF (805.5 KB) | EPUB
  • 1369 Views
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Correction

Correction
Correction
Page: 1492
Published online: 26 May 2019
CitationforCorrection | Full Text | PDF (99.8 KB) | EPUB
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