https://orcid.org/0000-0002-9453-4614View further author informationFigure 1. Kinase-phosphatase crosstalk in autophagy regulation. ULK1 and PPP2 are linked via a positive feedback mechanism, ULK1 activating PPP2 by phosphorylation of STRN, which in turn removes inhibitory MTORC1 sites on ULK1 itself. How ULK1 affects additional phosphatases like PPP5 and PPP6, and if this has an influence on autophagy regulation is currently not known.
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
