Autophagy, Volume 18, Issue 2 (2022)

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Autophagy, Volume 18, Issue 2 (2022)

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Editor’s Corner

Editorial
The RB1CC1 Claw-binding motif: a new piece in the puzzle of autophagy regulation
Hana Popelka & Daniel J. Klionsky
Pages: 237-239
Published online: 08 Feb 2022
AbstractforThe RB1CC1 Claw-binding motif: a new piece in the puzzle of autophagy regulation | Full Text | References | PDF (451 KB) | EPUB
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Review

Article
The influence of circular RNAs on autophagy and disease progression
Yian Wang, Yongzhen Mo, Miao Peng, Shanshan Zhang, Zhaojian Gong, Qijia Yan, Yanyan Tang, Yi He, Qianjin Liao, Xiayu Li, Xu Wu, Bo Xiang, Ming Zhou, Yong Li, Guiyuan Li, Xiaoling Li, Zhaoyang Zeng, Can Guo & Wei Xiong
Pages: 240-253
Published online: 27 Apr 2021
AbstractforThe influence of circular RNAs on autophagy and disease progression | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 4957 Views
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Autophagy and ALS: mechanistic insights and therapeutic implications
Jason P. Chua, Hortense De Calbiac, Edor Kabashi & Sami J. Barmada
Pages: 254-282
Published online: 31 May 2021
AbstractforAutophagy and ALS: mechanistic insights and therapeutic implications | Full Text | References | PDF (1.8 MB) | EPUB
  • 15200 Views
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Open Access
Autophagy in metabolism and quality control: opposing, complementary or interlinked functions?
Vojo Deretic & Guido Kroemer
Pages: 283-292
Published online: 22 Jun 2021
AbstractforAutophagy in metabolism and quality control: opposing, complementary or interlinked functions? | Full Text | References | PDF (1.2 MB) | EPUB
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Research Paper

Article
Autophagy induction during stem cell activation plays a key role in salivary gland self-renewal
Idil Orhon, Cecilia Rocchi, Beatriz Villarejo-Zori, Paola Serrano Martinez, Mirjam Baanstra, Uilke Brouwer, Patricia Boya, Rob Coppes & Fulvio Reggiori
Pages: 293-308
Published online: 19 May 2021
AbstractforAutophagy induction during stem cell activation plays a key role in salivary gland self-renewal | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 3758 Views
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Article
AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner
Wei Huang, Na Li, Yi Zhang, Xu Wang, Miao Yin & Qun-Ying Lei
Pages: 309-319
Published online: 16 May 2021
AbstractforAHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 3020 Views
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Article
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway
Lujia Feng, Liang Liang, Shaochong Zhang, Jinglu Yang, Yanan Yue & Xuedong Zhang
Pages: 320-339
Published online: 24 May 2021
AbstractforHMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway | Full Text | References | PDF (8.3 MB) | EPUB | Supplemental
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Article
BECN2 (beclin 2) Negatively Regulates Inflammasome Sensors Through ATG9A-Dependent but ATG16L1- and LC3-Independent Non-Canonical Autophagy
Guangtong Deng, Chaoran Li, Lang Chen, Changsheng Xing, Chuntang Fu, Chen Qian, Xin Liu, Helen Y. Wang, Motao Zhu & Rong-Fu Wang
Pages: 340-356
Published online: 21 Jun 2021
AbstractforBECN2 (beclin 2) Negatively Regulates Inflammasome Sensors Through ATG9A-Dependent but ATG16L1- and LC3-Independent Non-Canonical Autophagy | Full Text | References | PDF (4.3 MB) | EPUB | Supplemental
  • 3910 Views
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Article
CCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradation
Xueyu Wang, Zhiqiang Wei, Tingyu Lan, Yulin He, Bin Cheng, Ruimin Li, Hongxia Chen, Fahong Li, Guohua Liu, Bin Jiang, Yong Lin, Mengji Lu & Zhongji Meng
Pages: 357-374
Published online: 30 Jun 2021
AbstractforCCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradation | Full Text | References | PDF (7 MB) | EPUB | Supplemental
  • 5051 Views
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Open Access
Article
TOR and MAP kinase pathways synergistically regulate autophagy in response to nutrient depletion in fission yeast
Cristina Corral-Ramos, Rubén Barrios, José Ayté & Elena Hidalgo
Pages: 375-390
Published online: 23 Jun 2021
AbstractforTOR and MAP kinase pathways synergistically regulate autophagy in response to nutrient depletion in fission yeast | Full Text | References | PDF (5.3 MB) | EPUB | Supplemental
  • 1914 Views
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Article
Epigenetic reader BRD4 supports mycobacterial pathogenesis by co-modulating host lipophagy and angiogenesis
Tanushree Mukherjee, Bharat Bhatt, Praveen Prakhar, Gaurav Kumar Lohia, R.S. Rajmani & Kithiganahalli Narayanaswamy Balaji
Pages: 391-408
Published online: 28 Jun 2021
AbstractforEpigenetic reader BRD4 supports mycobacterial pathogenesis by co-modulating host lipophagy and angiogenesis | Full Text | References | PDF (8.4 MB) | EPUB | Supplemental
  • 1973 Views
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Article
Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction
Chenran Wang, Michael Haas, Syn Kok Yeo, Salwa Sebti, Álvaro F Fernández, Zhongju Zou, Beth Levine & Jun-Lin Guan
Pages: 409-422
Published online: 08 Jun 2021
AbstractforEnhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
  • 1983 Views
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Article
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders
Katrin Linda, Elly I. Lewerissa, Anouk H. A. Verboven, Michele Gabriele, Monica Frega, Teun M. Klein Gunnewiek, Lynn Devilee, Edda Ulferts, Marina Hommersom, Astrid Oudakker, Chantal Schoenmaker, Hans van Bokhoven, Dirk Schubert, Giuseppe Testa, David A. Koolen, Bert B.A. de Vries & Nael Nadif Kasri
Pages: 423-442
Published online: 21 Jul 2021
AbstractforImbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders | Full Text | References | PDF (4.3 MB) | EPUB | Supplemental
  • 7444 Views
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Commentary and Views

Article Commentary
The necessity of nucleophagic modality
Dalibor Mijaljica & Daniel J. Klionsky
Pages: 443-448
Published online: 13 Oct 2021
AbstractforThe necessity of nucleophagic modality | Full Text | References | PDF (277.5 KB) | EPUB
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Autophagic Punctum

Article Commentary
Beyond mitophagy: mitochondrial-derived vesicles can get the job done!
Payel Mondal & Christina Towers
Pages: 449-451
Published online: 15 Nov 2021
AbstractforBeyond mitophagy: mitochondrial-derived vesicles can get the job done! | Full Text | References | PDF (1.6 MB) | EPUB
  • 1397 Views
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Article Commentary
Innate host defense mechanisms SAC bacteria by regulating phosphoinositide kinases and phosphatases
Kimberly L. Carey, Kai Liu & Ramnik J. Xavier
Pages: 452-454
Published online: 23 Nov 2021
AbstractforInnate host defense mechanisms SAC bacteria by regulating phosphoinositide kinases and phosphatases | Full Text | References | PDF (292 KB) | EPUB
  • 882 Views
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Article Commentary
The complex interplay between ULK1 and protein phosphatases in autophagy regulation
Devanarayanan Siva Sankar, Zehan Hu & Joern Dengjel
Pages: 455-456
Published online: 28 Nov 2021
AbstractforThe complex interplay between ULK1 and protein phosphatases in autophagy regulation | Full Text | References | PDF (226 KB) | EPUB
  • 1047 Views
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Article Commentary
Genome-wide association studies of Arabidopsis dark-induced senescence reveals signatures of autophagy in metabolic reprogramming
Feng Zhu, Saleh Alseekh, Weiwei Wen, Yunjiang Cheng & Alisdair R. Fernie
Pages: 457-458
Published online: 15 Nov 2021
AbstractforGenome-wide association studies of Arabidopsis dark-induced senescence reveals signatures of autophagy in metabolic reprogramming | Full Text | References | PDF (202.7 KB) | EPUB
  • 1057 Views
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Article Commentary
An unexpected tumor suppressor role of SQSTM1/p62 in liver tumorigenesis
Xiaojuan Chao, Hong-Min Ni & Wen-Xing Ding
Pages: 459-461
Published online: 06 Dec 2021
AbstractforAn unexpected tumor suppressor role of SQSTM1/p62 in liver tumorigenesis | Full Text | References | PDF (694.3 KB) | EPUB
  • 905 Views
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Article Commentary
TFEB-dependent autophagy is involved in scavenger receptor OLR1/LOX-1-mediated tumor progression
Can Li & Lan Wang
Pages: 462-464
Published online: 22 Dec 2021
AbstractforTFEB-dependent autophagy is involved in scavenger receptor OLR1/LOX-1-mediated tumor progression | Full Text | References | PDF (472.4 KB) | EPUB
  • 1982 Views
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Article Commentary
Fuel for emotion: how mitophagy in the BLA can mediate increased anxiety in stressful social situations
James Johnson & Zheng Li
Pages: 465-466
Published online: 19 Dec 2021
AbstractforFuel for emotion: how mitophagy in the BLA can mediate increased anxiety in stressful social situations | Full Text | References | PDF (342.6 KB) | EPUB
  • 917 Views
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Article Commentary
GAK and PRKCD kinases regulate basal mitophagy
Michael J. Munson, Benan J. Mathai, Matthew Yoke Wui Ng, Laura Trachsel-Moncho, Laura R. de la Ballina & Anne Simonsen
Pages: 467-469
Published online: 09 Jan 2022
AbstractforGAK and PRKCD kinases regulate basal mitophagy | Full Text | References | PDF (526.9 KB) | EPUB
  • 3524 Views
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Correction

Correction
Correction
Page: 470
Published online: 08 Jun 2021
CitationforCorrection | Full Text | PDF (1.2 MB) | EPUB
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