Glucose-6-phosphate dehydrogenase deficiency screening and gene analysis in blood donors of Guangdong province

Figures & data

Table 1. Blood donation of blood donors with G6PD deficiency.

Sex	G6PD-deficient blood donors (n)	Donation times (n)	Total volume (ml)
Male	137	468	156,900
Female	75	216	61,900
Total	212	684	218,800

Table 2. Accumulative donation times of G6PD-deficient blood donors.

Donation times for every donors (n)	Number, n (M/F)^a	Total donation times, n (M/F)^a	Total volume of blood (ml) (M/F)^a
>10	8 (7/1)	153 (137/16)	60,600 (54,400/6200)
2–10	109 (73/36)	436(274/162)	129,400 (84,400/45,000)
1	95 (57/38)	95(57/38)	28,800 (17,500/11300)

^a M/F, male/female.

Table 3. G6PD gene mutation and distribution in 82 cases.

Mutations	Male (n)	Female (n)		Number of alleles (n)
	Hemizygote	Heterozygote	Homozygote
c.1388G > A (Kaiping)	16	9	1	27
c.1376G > T (Canton)	17	6	2	27
c.95A > G (Gaohe)	7	8	0	15
c.1024C > T (Chinese-5)	3	2	0	5
c.871G > A (Viangchan)	3	1	0	4
c.392G > T (Qingyuan)	2	1	0	3
c.517C > T (NanKang)	2	0	0	2
c.592C > T (Shunde)	1	0	0	1
c.392G > T/c.1311	1	0	0	1
C > T/IVS-11 93 T > C
Total	52	27	3	85^a

^a A total of 85 alleles were detected in 82 cases.