Hematology, Volume 27, Issue 1 (2022)

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Hematology, Volume 27, Issue 1 (2022)

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Research Article

Article
SPRY1 promotes cell proliferation and inhibits apoptosis by activating Hedgehog pathway in acute myeloid leukemia
Guiyang Lv, Yuanyuan Wang, ChunXiao Ji, Chunlei Shi & Ying Li
Pages: 1-10
Published online: 27 Dec 2021
AbstractforSPRY1 promotes cell proliferation and inhibits apoptosis by activating Hedgehog pathway in acute myeloid leukemia | Full Text | References | PDF (3.2 MB) | EPUB
  • 2689 Views
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Open Access
Article
Circ_0000745 promotes acute lymphoblastic leukemia progression through mediating miR-494-3p/NET1 axis
Xi Yang, Yanbi Li, Yi Zhang & Jingzhen Liu
Pages: 11-22
Published online: 27 Dec 2021
AbstractforCirc_0000745 promotes acute lymphoblastic leukemia progression through mediating miR-494-3p/NET1 axis | Full Text | References | PDF (3.3 MB) | EPUB
  • 4286 Views
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Open Access
Article
Updated recommendations on the use of ruxolitinib for the treatment of myelofibrosis
Timothy Devos, Dominik Selleslag, Nikki Granacher, Violaine Havelange & Fleur Samantha Benghiat
Pages: 23-31
Published online: 27 Dec 2021
AbstractforUpdated recommendations on the use of ruxolitinib for the treatment of myelofibrosis | Full Text | References | PDF (1 MB) | EPUB
  • 9318 Views
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Open Access
Article
PON2 blockade overcomes dexamethasone resistance in acute lymphoblastic leukemia
Pei-Ye Hui, Yan-Hua Chen, Jing Qin & Xiao-Hua Jiang
Pages: 32-42
Published online: 27 Dec 2021
AbstractforPON2 blockade overcomes dexamethasone resistance in acute lymphoblastic leukemia | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 2908 Views
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Open Access
Article
Downregulation of Smad4 expression confers chemoresistance against imatinib mesylate to chronic myeloid leukemia K562 cells
Jiangzhao Zhang, Min Zhang, Yan Liang, Min Liu & Zhiping Huang
Pages: 43-52
Published online: 27 Dec 2021
AbstractforDownregulation of Smad4 expression confers chemoresistance against imatinib mesylate to chronic myeloid leukemia K562 cells | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 2259 Views
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Open Access
Article
Efficacy and safety of adding gemtuzumab ozogamicin to conventional chemotherapy for adult acute myeloid leukemia: a systematic review and meta-analysis
Yuancheng Guo, Lijuan Deng, Yanhong Qiao & Bei Liu
Pages: 53-64
Published online: 27 Dec 2021
AbstractforEfficacy and safety of adding gemtuzumab ozogamicin to conventional chemotherapy for adult acute myeloid leukemia: a systematic review and meta-analysis | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
  • 4015 Views
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Open Access

Letter to the Editor

Clinical, laboratory and genetic features of Erdheim-Chester disease patients: analysis of a retrospective cohort of two reference centers in Latin America
Antonio Adolfo Guerra Soares Brandão, André Ramires Neder Abdo, Luís Alberto de Pádua Covas Lage, Giancarlo Fatobene, Juliana Pereira & Vanderson Rocha
Pages: 65-69
Published online: 27 Dec 2021
AbstractforClinical, laboratory and genetic features of Erdheim-Chester disease patients: analysis of a retrospective cohort of two reference centers in Latin America | Full Text | References | PDF (552 KB) | EPUB
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Open Access

Research Article

Article
Inferior survival and frequent hepatic dysfunction in non-Hodgkin’s lymphoma patients with HBV infection: a systematic review and meta-analysis
Min-Yue Zhang, Fei Gao, Yan-Wei Zhao, Bei-Wen Ni, Hong-Hui Huang & Jian Hou
Pages: 70-79
Published online: 27 Dec 2021
AbstractforInferior survival and frequent hepatic dysfunction in non-Hodgkin’s lymphoma patients with HBV infection: a systematic review and meta-analysis | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 3266 Views
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Open Access
Article
Joint status and related risk factors in patients with severe hemophilia A: a single-center cross-sectional study
Liang Zhao, Hongbin Yang, Yaochun Li, Zhongqing Wang, Li Zhou, Xielan Zhao & Jie Peng
Pages: 80-87
Published online: 29 Dec 2021
AbstractforJoint status and related risk factors in patients with severe hemophilia A: a single-center cross-sectional study | Full Text | References | PDF (1.2 MB) | EPUB
  • 3246 Views
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Open Access
Article
Pomalidomide-based therapy for extramedullary multiple myeloma
Yating Li, Jiamei Ji, Hua Lu, Jianyong Li & Xiaoyan Qu
Pages: 88-94
Published online: 24 Jan 2022
AbstractforPomalidomide-based therapy for extramedullary multiple myeloma | Full Text | References | PDF (1.2 MB) | EPUB
  • 3158 Views
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Open Access
Article
The efficacy of low-dose warfarin initiation (3 mg versus 5 mg) in newly diagnosed venous thromboembolism patients among a population with a high prevalence of warfarin-sensitive haplotype of the VKORC1 gene: a randomized controlled trial
Bundarika Suwanawiboon, Wannaphorn Rotchanapanya, Komkrit Mahaprom, Wanna Thongnoppakhun, Yupaporn Lalerd, Chanin Limwongse, Nuttawut Sermsathanasawadi & Weerapat Owattanapanich
Pages: 95-104
Published online: 24 Jan 2022
AbstractforThe efficacy of low-dose warfarin initiation (3 mg versus 5 mg) in newly diagnosed venous thromboembolism patients among a population with a high prevalence of warfarin-sensitive haplotype of the VKORC1 gene: a randomized controlled trial | Full Text | References | PDF (1.7 MB) | EPUB
  • 2781 Views
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Open Access
Article
Application of new targeted drugs in relapsed/refractory primary central nervous system lymphoma
Ying Zhou & Xiaohong Xu
Pages: 105-112
Published online: 24 Jan 2022
AbstractforApplication of new targeted drugs in relapsed/refractory primary central nervous system lymphoma | Full Text | References | PDF (746.8 KB) | EPUB
  • 3956 Views
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Open Access
Article
Clinical characteristics of 512 eculizumab-naive paroxysmal nocturnal hemoglobinuria patients in China: a single-center observational study
Yali Du, Yuan Yang, Chen Yang, Miao Chen & Bing Han
Pages: 113-121
Published online: 24 Jan 2022
AbstractforClinical characteristics of 512 eculizumab-naive paroxysmal nocturnal hemoglobinuria patients in China: a single-center observational study | Full Text | References | PDF (913 KB) | EPUB
  • 3663 Views
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Open Access
Article
Prognostic significance of CD56 expression in patients with multiple myeloma: a meta-analysis
Lijuan Zhang, Yun Huang, Yun Lin, Aili Zhang, Rong Zou, Huiying Xu & Sili Wang
Pages: 122-131
Published online: 24 Jan 2022
AbstractforPrognostic significance of CD56 expression in patients with multiple myeloma: a meta-analysis | Full Text | References | PDF (1.5 MB) | EPUB
  • 3226 Views
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Open Access
Article
Overview of current progress and challenges in diagnosis, and management of pediatric sickle cell disease in Democratic Republic of the Congo
Emmanuel Tebandite Kasai, Jean Pierre Alworong’a Opara, Justin Ntokamunda Kadima, Masendu Kalenga, Salomon Batina Agasa, Roland Marini Djang’eing‘a & François Boemer
Pages: 132-140
Published online: 24 Jan 2022
AbstractforOverview of current progress and challenges in diagnosis, and management of pediatric sickle cell disease in Democratic Republic of the Congo | Full Text | References | PDF (1.1 MB) | EPUB
  • 3641 Views
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Open Access
Article
Comparison of early mortality between leukapheresis and non-leukapheresis in adult acute myeloid leukemia patients with hyperleukocytosis: a systematic review and meta-analysis
Ikhwan Rinaldi, Noorwati Sutandyo & Kevin Winston
Pages: 141-149
Published online: 24 Jan 2022
AbstractforComparison of early mortality between leukapheresis and non-leukapheresis in adult acute myeloid leukemia patients with hyperleukocytosis: a systematic review and meta-analysis | Full Text | References | PDF (1.7 MB) | EPUB
  • 3314 Views
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Open Access
Article
Molecular epidemiological investigation of abnormal hemoglobin in Shaokwan region, southern China
Hui Yang, Min Lin, Fen Lin, Zhan-Zhong Ma, Xiao-Fen Zhan & Li-Ye Yang
Pages: 150-156
Published online: 24 Jan 2022
AbstractforMolecular epidemiological investigation of abnormal hemoglobin in Shaokwan region, southern China | Full Text | References | PDF (2 MB) | EPUB
  • 1615 Views
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Open Access
Article
Validation and reliability of current guidelines for the treatment of essential thrombocythemia under real-world clinical settings in Japan
Terumi Baba, Yoshinori Hashimoto, Hajime Yasuda, Marito Araki, Yoko Edahiro, Soji Morishita, Tomonori Ochiai, Shuichi Shirane, Jun Ando & Norio Komatsu
Pages: 157-166
Published online: 24 Jan 2022
AbstractforValidation and reliability of current guidelines for the treatment of essential thrombocythemia under real-world clinical settings in Japan | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 2517 Views
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Open Access
Article
Effectiveness of lymphoplasmapheresis compared with therapeutic plasma exchange for thrombotic thrombocytopenic purpura: a retrospective evaluation
Zhimin Zhang, Xi Yuan, Yuanjun Jiang, Ning Li & Bijuan Li
Pages: 167-172
Published online: 24 Jan 2022
AbstractforEffectiveness of lymphoplasmapheresis compared with therapeutic plasma exchange for thrombotic thrombocytopenic purpura: a retrospective evaluation | Full Text | References | PDF (585.1 KB) | EPUB | Supplemental
  • 2098 Views
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Open Access
Article
miR-140-3p attenuated the tumorigenesis of multiple myeloma via attenuating BZW2
Xingxing Long, Junjun Li, Feng Wen, Yixiong Cao, Zeyu Luo & Cong Luo
Pages: 173-180
Published online: 24 Jan 2022
AbstractformiR-140-3p attenuated the tumorigenesis of multiple myeloma via attenuating BZW2 | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 1956 Views
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Open Access
Article
Post-treatment anti-Mullerian hormone (AMH) levels predict long-term ovarian dysfunction in women with hematological malignancies
Sunisa Kongkiatkamon, Anothai Chintabanyat, Chantana Polprasert, Noppacharn Uaprasert & Ponlapat Rojnuckarin
Pages: 181-186
Published online: 24 Jan 2022
AbstractforPost-treatment anti-Mullerian hormone (AMH) levels predict long-term ovarian dysfunction in women with hematological malignancies | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 2670 Views
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Open Access
Article
The effect of marital status on the survival of patients with multiple myeloma
Lina Tang, Zhenyu Pan & Xiaoxia Zhang
Pages: 187-197
Published online: 24 Jan 2022
AbstractforThe effect of marital status on the survival of patients with multiple myeloma | Full Text | References | PDF (1.9 MB) | EPUB
  • 2656 Views
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Open Access
Article
Accurate detection of α-globin gene copy number variants with two reactions using droplet digital PCR
Xiuqin Bao, Danqing Qin, Jian Ma, Xiangcheng Zhou, Jicheng Wang, Cuize Yao, Liang Zhang & Li Du
Pages: 198-203
Published online: 31 Jan 2022
AbstractforAccurate detection of α-globin gene copy number variants with two reactions using droplet digital PCR | Full Text | References | PDF (1.2 MB) | EPUB
  • 2760 Views
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Open Access

Rapid Communication

Rapid Communication
Outcomes of anti-CD38 isatuximab plus pomalidomide and dexamethasone in five relapsed myeloma patients with prior exposure to anti-C38 daratumumab: case series
Faouzi Djebbari, Matt Poynton, Gina Sangha, Laura Anderson, Rebecca Maddams, Toby A. Eyre, Grant Vallance, Supratik Basu & Karthik Ramasamy
Pages: 204-207
Published online: 08 Feb 2022
AbstractforOutcomes of anti-CD38 isatuximab plus pomalidomide and dexamethasone in five relapsed myeloma patients with prior exposure to anti-C38 daratumumab: case series | Full Text | References | PDF (484.7 KB) | EPUB
  • 5032 Views
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Open Access

Research Article

Article
Prevalence of G6PD deficiency in Thai blood donors, the characteristics of G6PD deficient blood, and the efficacy of fluorescent spot test to screen for G6PD deficiency in a hospital blood bank setting
Phinyada Rojphoung, Thongbai Rungroung, Usanee Siriboonrit, Sasijit Vejbaesya, Parichart Permpikul & Janejira Kittivorapart
Pages: 208-213
Published online: 08 Feb 2022
AbstractforPrevalence of G6PD deficiency in Thai blood donors, the characteristics of G6PD deficient blood, and the efficacy of fluorescent spot test to screen for G6PD deficiency in a hospital blood bank setting | Full Text | References | PDF (744.2 KB) | EPUB
  • 2439 Views
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Open Access
Article
Bioinformatics analysis deciphering the transcriptomic signatures associated with signalling pathways and prognosis in the myelodysplastic syndromes
Niluopaer Tuerxun, Jie Wang, Fang Zhao, Yu-ting Qin, Huan Wang, Rong Chen & Jian-ping Hao
Pages: 214-231
Published online: 08 Feb 2022
AbstractforBioinformatics analysis deciphering the transcriptomic signatures associated with signalling pathways and prognosis in the myelodysplastic syndromes | Full Text | References | PDF (6.7 MB) | EPUB | Supplemental
  • 3377 Views
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Open Access
Article
Highly specific functional equivalence of XN-HPC for optimum CD34+ cell count in harvested allogeneic bone marrow stem cell products
Aisha Jamal, Tahir Khan, Uzma Zaidi, Quratul Ain Rizvi, Shafaq Jahanzeb, Ali Salim, Mehjabeen Imam & Tahir Shamsi
Pages: 232-238
Published online: 13 Feb 2022
AbstractforHighly specific functional equivalence of XN-HPC for optimum CD34+ cell count in harvested allogeneic bone marrow stem cell products | Full Text | References | PDF (763.2 KB) | EPUB | Supplemental
  • 1937 Views
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Open Access
Article
Bortezomib-cyclophosphamide-dexamethasone induction/consolidation and bortezomib maintenance for transplant-eligible newly diagnosed multiple myeloma: phase 2 multicenter trial
Hiroyuki Muranushi, Junya Kanda, Masayuki Kobayashi, Takeshi Maeda, Toshiyuki Kitano, Masaaki Tsuji, Yasunori Ueda, Takayuki Ishikawa, Masaharu Nohgawa, Mitsumasa Watanabe, Kazunori Imada, Toshinori Moriguchi, Mitsuru Itoh, Hitoshi Ohno, Akihito Yonezawa, Hirokazu Hirata, Nobuyoshi Arima, Kohsuke Asagoe, Naoyuki Anzai, Kayoko Nagata, Shinji Yasuno, Yoshihiro Kuwabara, Hiromi Kitao, Ihhwa Kim, Kiyomi Kawagishi, Kenji Ueshima, Shinjiro Tominari, Takeo Nakayama, Kouhei Yamashita & Akifumi Takaori-Kondo
Pages: 239-248
Published online: 13 Feb 2022
AbstractforBortezomib-cyclophosphamide-dexamethasone induction/consolidation and bortezomib maintenance for transplant-eligible newly diagnosed multiple myeloma: phase 2 multicenter trial | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 3672 Views
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Open Access
Article
Venetoclax-based combinations for acute myeloid leukemia: optimizing their use in Latin-America
Andrés Gómez-De León, Roberta Demichelis-Gómez, Alfredo Pinedo-Rodríguez, Daniel Enriquez-Vera, Juan Antonio Flores-Jiménez, Adrián Alejandro Ceballos-López, Margarita Rodríguez-Mejorada, Miguel Angel Herrera Riojas, Roberto Ovilla-Martínez, Pamela Báez-Islas, Xóchitl Cota-Rangel, Yvette Neme-Yunes, Sergio Inclán-Alarcón, Nelson J. López-Flores, Perla R. Colunga-Pedraza, Anna C. Rodríguez-Zúñiga & David Gómez-Almaguer
Pages: 249-257
Published online: 22 Feb 2022
AbstractforVenetoclax-based combinations for acute myeloid leukemia: optimizing their use in Latin-America | Full Text | References | PDF (1.3 MB) | EPUB
  • 3446 Views
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Open Access

Case Report

Case Report
The first Chinese case of unstable Hemoglobin Santa Ana detected by capillary electrophoresis: a case report and literature review
Li Du, Danqing Qin, Jicheng Wang, Cuize Yao, Juan Zhu, Hao Guo, Tenglong Yuan, Jie Liang & Aihua Yin
Pages: 258-262
Published online: 22 Feb 2022
AbstractforThe first Chinese case of unstable Hemoglobin Santa Ana detected by capillary electrophoresis: a case report and literature review | Full Text | References | PDF (908.7 KB) | EPUB
  • 2274 Views
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Open Access

Research Article

Article
Comparison of transcriptome profiles of nucleated red blood cells in cord blood between preterm and full-term neonates
Yuanyuan Han, Ling Huang, Man Zhou, Xiaoyu Tan, Shangjin Gong, Zhaojun Zhang, Tingting Jin, Xiangdong Fang, Yankai Jia & S. W. Huang
Pages: 263-273
Published online: 22 Feb 2022
AbstractforComparison of transcriptome profiles of nucleated red blood cells in cord blood between preterm and full-term neonates | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 2802 Views
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Open Access
Article
Tetrandrine overcomes drug resistance mediated by bone marrow microenvironment by regulating the expression of P-glycoprotein in acute leukemia
Xinyi Zhou, Nan Jin & Baoan Chen
Pages: 274-279
Published online: 22 Feb 2022
AbstractforTetrandrine overcomes drug resistance mediated by bone marrow microenvironment by regulating the expression of P-glycoprotein in acute leukemia | Full Text | References | PDF (883.1 KB) | EPUB
  • 1988 Views
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Open Access
Article
Comprehensive bioinformatics analysis reveals the hub genes and pathways associated with multiple myeloma
Shengli Zhao, Xiaoyi Mo, Zhenxing Wen, Lijuan Ren, Zhipeng Chen, Wei Lin, Qi Wang, Shaoxiong Min & Bailing Chen
Pages: 280-292
Published online: 22 Feb 2022
AbstractforComprehensive bioinformatics analysis reveals the hub genes and pathways associated with multiple myeloma | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 6409 Views
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Open Access
Article
Primary graft failure following allogeneic hematopoietic stem cell transplantation: risk factors, treatment and outcomes
Juan Chen, Aiming Pang, Yuanqi Zhao, Li Liu, Runzhi Ma, Jialin Wei, Xin Chen, Yi He, Donglin Yang, Rongli Zhang, Weihua Zhai, Qiaoling Ma, Erlie Jiang, Mingzhe Han, Jiaxi Zhou & Sizhou Feng
Pages: 293-299
Published online: 22 Feb 2022
AbstractforPrimary graft failure following allogeneic hematopoietic stem cell transplantation: risk factors, treatment and outcomes | Full Text | References | PDF (954.5 KB) | EPUB | Supplemental
  • 5287 Views
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Open Access
Article
Gemtuzumab ozogamicin (GO) as monotherapy and in combination with hypomethylation agents in the treatment of acute myeloid leukemia: a systematic meta-analysis
Jun Li & Xiaoping Yin
Pages: 300-309
Published online: 27 Feb 2022
AbstractforGemtuzumab ozogamicin (GO) as monotherapy and in combination with hypomethylation agents in the treatment of acute myeloid leukemia: a systematic meta-analysis | Full Text | References | PDF (2.6 MB) | EPUB
  • 2830 Views
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Open Access
Article
Encouraging the outcomes of children with beta-thalassaemia major who underwent fresh cord blood transplantation from an HLA-matched sibling donor
Jianyun Wen, Xiaodong Wang, Libai Chen, Yuelin He, Xiaoqin Feng, Chunfu Li, Yongshen Ruan, Sixi Liu & Xuedong Wu
Pages: 310-317
Published online: 28 Feb 2022
AbstractforEncouraging the outcomes of children with beta-thalassaemia major who underwent fresh cord blood transplantation from an HLA-matched sibling donor | Full Text | References | PDF (998.7 KB) | EPUB
  • 2549 Views
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Open Access

Case Report

Case Report
A journey through anticoagulant therapies in the treatment of left ventricular thrombus in post-COVID-19 heparin-induced thrombocytopenia: a case report
Alberto Lázaro-García, Inés Martínez-Alfonzo, Rosa Vidal-Laso, Diego Velasco-Rodríguez, Marta Tomás-Mallebrera, Marta González-Rodríguez & Pilar Llamas-Sillero
Pages: 318-321
Published online: 01 Mar 2022
AbstractforA journey through anticoagulant therapies in the treatment of left ventricular thrombus in post-COVID-19 heparin-induced thrombocytopenia: a case report | Full Text | References | PDF (708.4 KB) | EPUB
  • 3267 Views
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Open Access

Research Article

Article
Identification of biomarkers for early diagnosis of multiple myeloma by weighted gene co-expression network analysis and their clinical relevance
Mengling Xu, Ye Meng, Qian Li, Alice Charwudzi, Hui Qin & Shudao Xiong
Pages: 322-331
Published online: 01 Mar 2022
AbstractforIdentification of biomarkers for early diagnosis of multiple myeloma by weighted gene co-expression network analysis and their clinical relevance | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 3326 Views
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Open Access

Case Report

Case Report
False positive results: a challenge for laboratory physicians and hematologists in treating multiple myeloma with daratumumab
Shanshan Liang, Weihua Feng, Hongbing Ma, Li Zhang & Chengyao Jia
Pages: 332-336
Published online: 07 Mar 2022
AbstractforFalse positive results: a challenge for laboratory physicians and hematologists in treating multiple myeloma with daratumumab | Full Text | References | PDF (903.7 KB) | EPUB
  • 3875 Views
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Research Article

Article
A correlation of thrombin generation assay and clot waveform analysis in patients on warfarin
May Anne Cheong, Chuen Wen Tan, Wan Hui Wong, Ming Chai Kong, Edmund See, Shu Hui Yeang, Sei Keng Koh, Yuan Tying Shim, Lai Heng Lee & Heng Joo Ng
Pages: 337-342
Published online: 07 Mar 2022
AbstractforA correlation of thrombin generation assay and clot waveform analysis in patients on warfarin | Full Text | References | PDF (916.6 KB) | EPUB
  • 1633 Views
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Open Access
Article
Promising therapeutic approaches for relapsed/refractory multiple myeloma
Beiwen Ni & Jian Hou
Pages: 343-352
Published online: 14 Mar 2022
AbstractforPromising therapeutic approaches for relapsed/refractory multiple myeloma | Full Text | References | PDF (800.6 KB) | EPUB
  • 5423 Views
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Article
Noninvasive prenatal testing of beta-thalassemia for common Pakistani mutations: a comparative study using cell-free fetal DNA from maternal plasma and chorionic villus sampling
Muhammad Afzal, Muhammad Abdul Naeem, Suhaib Ahmed, Nayyar Amin, Amena Rahim, Manazza Munawar, Mansoor Ishaq, Ali Rathore & K. Maria
Pages: 353-359
Published online: 14 Mar 2022
AbstractforNoninvasive prenatal testing of beta-thalassemia for common Pakistani mutations: a comparative study using cell-free fetal DNA from maternal plasma and chorionic villus sampling | Full Text | References | PDF (963.8 KB) | EPUB
  • 3570 Views
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Article
Real-world experience of treatment with thrombopoietin receptor agonists in anti-thymocyte globulin-naïve patients with aplastic anemia: an observational retrospective analysis in a single institution
Masaki Iino, Atsushi Jinguji, Tomoya Sato & Ayato Nakadate
Pages: 360-366
Published online: 20 Mar 2022
AbstractforReal-world experience of treatment with thrombopoietin receptor agonists in anti-thymocyte globulin-naïve patients with aplastic anemia: an observational retrospective analysis in a single institution | Full Text | References | PDF (927.3 KB) | EPUB
  • 3135 Views
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Article
The prognostic value of the interaction between ASXL1 and TET2 gene mutations in patients with chronic myelomonocytic leukemia: a meta-analysis
Wenxia Zhao, Conghui Zhang, Yiming Li, Yang Li, Yang Liu, Xiaoyu Sun, Mingyan Liu & Rongguang Shao
Pages: 367-378
Published online: 20 Mar 2022
AbstractforThe prognostic value of the interaction between ASXL1 and TET2 gene mutations in patients with chronic myelomonocytic leukemia: a meta-analysis | Full Text | References | PDF (1.8 MB) | EPUB
  • 2345 Views
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Article
Life-threatening bleeding in patients with hemophilia (PWH): a 10-year cohort study in Dakar, Senegal
Sokhna Aïssatou Touré, Moussa Seck, Diariatou Sy, Elimane Seydi Bousso, Blaise Felix Faye & Saliou Diop
Pages: 379-383
Published online: 20 Mar 2022
AbstractforLife-threatening bleeding in patients with hemophilia (PWH): a 10-year cohort study in Dakar, Senegal | Full Text | References | PDF (1.2 MB) | EPUB
  • 2253 Views
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Article
Serum immunoglobulin G as a discriminator of infection in follicular lymphoma patients undergoing chemotherapy with bendamustine in combination with rituximab
Akie Hirata, Kaname Miyashita, Takafumi Tanaka, Kiyoko Hirata, Taisuke Narazaki, Hayato Utsunomiya, Hirofumi Ohno, Eriko Nakashima, Yoshimichi Tachikawa, Ilseung Choi, Kenichi Taguchi & Youko Suehiro
Pages: 384-395
Published online: 28 Mar 2022
AbstractforSerum immunoglobulin G as a discriminator of infection in follicular lymphoma patients undergoing chemotherapy with bendamustine in combination with rituximab | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 2408 Views
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Article
Adult acute lymphoblastic leukemia in a resource-constrained setting: outcomes after expansion of genetic evaluation
Wellington F. Silva, Mariane T. Amano, Luiza L. Perruso, Maria Gabriella Cordeiro, Renata Kiyomi Kishimoto, Aline de Medeiros Leal, Luciana Nardinelli, Israel Bendit, Elvira DRP Velloso, Eduardo M. Rego & Vanderson Rocha
Pages: 396-403
Published online: 28 Mar 2022
AbstractforAdult acute lymphoblastic leukemia in a resource-constrained setting: outcomes after expansion of genetic evaluation | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 2220 Views
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Article
Efficacy and toxicity of SEAM (semustine, etoposide, cytarabine, and melphalan) conditioning regimen followed by autologous stem cell transplantation in lymphoma
Lihong Zhang, Haifei Yang, Chongsheng Qian, Jihao Zhou, Qian Zhu, Yibin Jiang, Shuo Liu, Xiaochen Chen, Ting Xu, Changju Qu, Caixia Li, Zhengming Jin, Jianhong Chu, Xinyou Zhang, Depei Wu & Haiwen Huang
Pages: 404-411
Published online: 12 Apr 2022
AbstractforEfficacy and toxicity of SEAM (semustine, etoposide, cytarabine, and melphalan) conditioning regimen followed by autologous stem cell transplantation in lymphoma | Full Text | References | PDF (959.7 KB) | EPUB
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Article
Assessment of the knowledge beliefs and associated factors among Saudi adults towards blood donation in Saudi Arabia
Wajid Syed, Ahmed Alsadoun, Adel S. Bashatah, Mahmood Basil A. Al-Rawi & Nasir Siddiqui
Pages: 412-419
Published online: 12 Apr 2022
AbstractforAssessment of the knowledge beliefs and associated factors among Saudi adults towards blood donation in Saudi Arabia | Full Text | References | PDF (963.4 KB) | EPUB
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Article
The favorable prognostic value of the loss of sex chromosomes in patients with t(8;21) acute myeloid leukemia: an exploratory study
Lixia Zhu, Rongrong Chen, Xueying Li, Mixue Xie, Xiudi Yang, Jianai Sun, Mingyu Zhu, Xiaolong Zheng, Li Li, Jingjing Zhu, De Zhou, Wanzhuo Xie & Xiujin Ye
Pages: 420-425
Published online: 12 Apr 2022
AbstractforThe favorable prognostic value of the loss of sex chromosomes in patients with t(8;21) acute myeloid leukemia: an exploratory study | Full Text | References | PDF (662.5 KB) | EPUB
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Article
Platelet to white blood cell ratio was an independent prognostic predictor in acute myeloid leukemia
Shuqi Zhao, Hanzhang Pan, Qi Guo, Wanzhuo Xie & Jinghan Wang
Pages: 426-430
Published online: 12 Apr 2022
AbstractforPlatelet to white blood cell ratio was an independent prognostic predictor in acute myeloid leukemia | Full Text | References | PDF (1,005.3 KB) | EPUB | Supplemental
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Article
Circ_KCNQ5 participates in the progression of childhood acute myeloid leukemia by enhancing the expression of RAB10 via binding to miR-622
Xiaoyan Hu, Jiaojiao Yin, Rui He, Rong Chao & Shengdong Zhu
Pages: 431-440
Published online: 12 Apr 2022
AbstractforCirc_KCNQ5 participates in the progression of childhood acute myeloid leukemia by enhancing the expression of RAB10 via binding to miR-622 | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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Article
Targeted next-generation sequencing revealed a novel homozygous mutation in the LRBA gene causes severe haemolysis associated with Inborn Errors of Immunity in an Indian family.
Prabhakar Kedar, Rashmi Dongerdiye, Shanmukhaiah Chandrakala, Umair Ahmed Bargir & Manisha Madkaikar
Pages: 441-448
Published online: 12 Apr 2022
AbstractforTargeted next-generation sequencing revealed a novel homozygous mutation in the LRBA gene causes severe haemolysis associated with Inborn Errors of Immunity in an Indian family. | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Article
High dose melphalan is an adequate preparative regimen for autologous hematopoietic stem cell transplantation in relapsed/refractory lymphoma
José A. Fernández-Gutiérrez, Oscar A. Reyes-Cisneros, Mark R. Litzow, Lorena Bojalil-Álvarez, Elizabeth García-Villaseñor, Eliezer Tomas Gómez-Gomez, Iván Murrieta-Álvarez, David Gomez-Almaguer, Cesar H. Gutierrez-Aguirre, Amado J. Karduss-Urueta, Guillermo J. Ruiz-Delgado & Guillermo José Ruiz-Argüelles
Pages: 449-455
Published online: 12 Apr 2022
AbstractforHigh dose melphalan is an adequate preparative regimen for autologous hematopoietic stem cell transplantation in relapsed/refractory lymphoma | Full Text | References | PDF (2.1 MB) | EPUB
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Article
Bioinformatics analysis of the expression and clinical significance of the NUP210 Gene in acute myeloid leukaemia
Mengqi Li & He Zhao
Pages: 456-462
Published online: 12 Apr 2022
AbstractforBioinformatics analysis of the expression and clinical significance of the NUP210 Gene in acute myeloid leukaemia | Full Text | References | PDF (1.5 MB) | EPUB
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Case Report

Case Report
Vitamin B6 deficiency as a cause of polyneuropathy in POEMS syndrome: rapid recovery with supplementation in two cases
Hajime Yasuda, Yoshiki Furukawa, Kenya Nishioka, Makoto Sasaki, Yutaka Tsukune, Shuichi Shirane, Nobutaka Hattori, Miki Ando & Norio Komatsu
Pages: 463-468
Published online: 12 Apr 2022
AbstractforVitamin B6 deficiency as a cause of polyneuropathy in POEMS syndrome: rapid recovery with supplementation in two cases | Full Text | References | PDF (1 MB) | EPUB
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Research Article

Article
H22954, a long non-coding RNA, inhibits glucose uptake in leukemia cells in a GLUT10-dependent manner
Yujia Bai, Bibo Ye, Tianyu Li, Rongrong Wang & Xiaofei Qi
Pages: 469-475
Published online: 12 Apr 2022
AbstractforH22954, a long non-coding RNA, inhibits glucose uptake in leukemia cells in a GLUT10-dependent manner | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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Article
Gene expression profiles and cytokine environments determine the in vitro proliferation and expansion capacities of human hematopoietic stem and progenitor cells
Roberto Dircio-Maldonado, Rosario Castro-Oropeza, Patricia Flores-Guzman, Alberto Cedro-Tanda, Fredy Omar Beltran-Anaya, Alfredo Hidalgo-Miranda & Hector Mayani
Pages: 476-487
Published online: 12 Apr 2022
AbstractforGene expression profiles and cytokine environments determine the in vitro proliferation and expansion capacities of human hematopoietic stem and progenitor cells | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Article
Attitudes and practices of unmarried adults towards sickle cell disease: emergent factors from a cross sectional study in Nigeria’s capital
Obi Peter Adigwe, Godspower Onavbavba & Solomon Oloche Onoja
Pages: 488-493
Published online: 18 Apr 2022
AbstractforAttitudes and practices of unmarried adults towards sickle cell disease: emergent factors from a cross sectional study in Nigeria’s capital | Full Text | References | PDF (528.9 KB) | EPUB
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Article
Glucose-6-phosphate dehydrogenase deficiency screening and gene analysis in blood donors of Guangdong province
Hong-Feng Liang, Fen Lin, Jin Lu, Zhi-Xiao Chen & Li-Ye Yang
Pages: 494-498
Published online: 24 Apr 2022
AbstractforGlucose-6-phosphate dehydrogenase deficiency screening and gene analysis in blood donors of Guangdong province | Full Text | References | PDF (458.6 KB) | EPUB
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Article
Prognostic impact of PRDM16 expression in acute myeloid leukemia with normal cytogenetics
Xin Xiang, Qiongyu Lu, Xiaoyu Xu, Ping Cai, Suning Chen, Jinlan Pan & Zhao Zeng
Pages: 499-505
Published online: 26 Apr 2022
AbstractforPrognostic impact of PRDM16 expression in acute myeloid leukemia with normal cytogenetics | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Article
Identification of key genes and miRNA-mRNA regulatory networks associated with bone marrow immune microenvironment regulations in multiple myeloma by integrative bioinformatics analysis
Niluopaer Tuerxun, Jie Wang, Yu-ting Qin, Fang Zhao, Huan Wang, Jian-hua Qu, Md. Nazim Uddin & Jian-ping Hao
Pages: 506-517
Published online: 10 May 2022
AbstractforIdentification of key genes and miRNA-mRNA regulatory networks associated with bone marrow immune microenvironment regulations in multiple myeloma by integrative bioinformatics analysis | Full Text | References | PDF (3 MB) | EPUB | Supplemental
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Case Report

Case Report
A short report of novel RARG-HNRNPM fusion gene in resembling acute promyelocytic leukemia
Yang Song, Jiangxue Hou, Li Wan, Kaiqi Liu, Chunlin Zhou, Shuning Wei, Guangji Zhang, Dong Lin, Yan Li, Qiuyun Fang, Yuntao Liu, Benfa Gong, Xiaoyuan Gong, Ying Wang, Hui Wei, Jianxiang Wang & Yingchang Mi
Pages: 518-522
Published online: 11 May 2022
AbstractforA short report of novel RARG-HNRNPM fusion gene in resembling acute promyelocytic leukemia | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Research Article

Article
Correlation of the transcription factors IRF4 and BACH2 with the abnormal NFATC1 expression in T cells from chronic myeloid leukemia patients
Yikai Zhang, Xiangbo Zeng, Xianfeng Zha, Jing Lai, Guangxiao Tan, Shaohua Chen, Xibao Yu, Yangqiu Li & Ling Xu
Pages: 523-529
Published online: 11 May 2022
AbstractforCorrelation of the transcription factors IRF4 and BACH2 with the abnormal NFATC1 expression in T cells from chronic myeloid leukemia patients | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Article
Clinical and molecular characteristics of acute myeloid leukemia with MPL mutation
Yu Chen, Jundan Xie, Zhen Shen, Jie Shi, Suning Chen & Gang Wang
Pages: 530-534
Published online: 11 May 2022
AbstractforClinical and molecular characteristics of acute myeloid leukemia with MPL mutation | Full Text | References | PDF (741.8 KB) | EPUB | Supplemental
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Article
Bendamustine treatment of haematological malignancies: significant risks of opportunistic viral, fungal and bacterial infections
Tony K.Y. Wu, Karen H.K. Tang, Yu-Yan Hwang, Thomas S.Y. Chan, Eric Tse & Yok-Lam Kwong
Pages: 535-542
Published online: 11 May 2022
AbstractforBendamustine treatment of haematological malignancies: significant risks of opportunistic viral, fungal and bacterial infections | Full Text | References | PDF (972.6 KB) | EPUB | Supplemental
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Article
Systemic loxoscelism induced warm autoimmune hemolytic anemia: clinical series and review
Brandon Calhoun, Andrew Moore, Andrew Dickey & D. Matthew Shoemaker
Pages: 543-554
Published online: 11 May 2022
AbstractforSystemic loxoscelism induced warm autoimmune hemolytic anemia: clinical series and review | Full Text | References | PDF (1.7 MB) | EPUB
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Article
Prognostic biomarker replication factor C subunit 5 and its correlation with immune infiltrates in acute myeloid leukemia
Wang-jun Li, Dong-wei Wu, Yi-feng Zhou, Chen-wei Zhang & Xiao-wei Liao
Pages: 555-564
Published online: 11 May 2022
AbstractforPrognostic biomarker replication factor C subunit 5 and its correlation with immune infiltrates in acute myeloid leukemia | Full Text | References | PDF (2.6 MB) | EPUB
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Article
Molecular genetic and clinical characterization of acute myeloid leukemia with trisomy 8 as the sole chromosome abnormality
Jie Liu, WenMin Han, Xiaohui Cai, Zheng Wang, LiuJun Cao, HaiYing Hua, ZhuXia Jia, HongYing Chao, XuZhang Lu & HongJie Shen
Pages: 565-574
Published online: 12 May 2022
AbstractforMolecular genetic and clinical characterization of acute myeloid leukemia with trisomy 8 as the sole chromosome abnormality | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Article
Establishment of a prediction model for disease progression within one year in newly diagnosed multiple myeloma patients
Huahua Wei, Zhihuang Sun, Xiaoying Ye, Jieni Yu, Yinhai Ye & Zifeng Wang
Pages: 575-582
Published online: 26 May 2022
AbstractforEstablishment of a prediction model for disease progression within one year in newly diagnosed multiple myeloma patients | Full Text | References | PDF (1 MB) | EPUB
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Article
Pediatric acute myeloid leukemia patients with KMT2A rearrangements: a single-center retrospective study
Wei Yang, Maoquan Qin, Chenguang Jia, Jun Yang, Wei Chen, Yanhui Luo, Yuanfang Jing & Bin Wang
Pages: 583-589
Published online: 26 May 2022
AbstractforPediatric acute myeloid leukemia patients with KMT2A rearrangements: a single-center retrospective study | Full Text | References | PDF (728.3 KB) | EPUB
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Article
Does glucose-6-phosphate dehydrogenase deficiency worsen the clinical features of sickle cell disease? A multi-hospital-based cross-sectional study
Paul Kambale-Kombi, Roland Marini Djang’eing’a, Jean-Pierre Alworong’a Opara, Jean-Marc Minon, Camille Atoba Bokele, Vincent Bours, Marie-Agnès Azerad, Serge Tonen-Wolyec, Charles Kayembe Tshilumba & Salomon Batina-Agasa
Pages: 590-595
Published online: 26 May 2022
AbstractforDoes glucose-6-phosphate dehydrogenase deficiency worsen the clinical features of sickle cell disease? A multi-hospital-based cross-sectional study | Full Text | References | PDF (739.3 KB) | EPUB
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Article
Lncrna ANGPTL1-3 and its target microRNA-30a exhibit potency as biomarkers for bortezomib response and prognosis in multiple myeloma patients
Fangfang Zhou & Liyin Guo
Pages: 596-602
Published online: 26 May 2022
AbstractforLncrna ANGPTL1-3 and its target microRNA-30a exhibit potency as biomarkers for bortezomib response and prognosis in multiple myeloma patients | Full Text | References | PDF (1.4 MB) | EPUB
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Case Report

Case Report
Copy number variation analysis using next-generation sequencing identifies the CFHR3/CFHR1 deletion in atypical hemolytic uremic syndrome: a case report
Joonhong Park, Ho-Young Yhim, Kyung Pyo Kang, Tae Won Bae & Yong Gon Cho
Pages: 603-608
Published online: 26 May 2022
AbstractforCopy number variation analysis using next-generation sequencing identifies the CFHR3/CFHR1 deletion in atypical hemolytic uremic syndrome: a case report | Full Text | References | PDF (1.1 MB) | EPUB
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Research Article

Article
Nucleophosmin 1: from its pathogenic role to a tantalizing therapeutic target in acute myeloid leukemia
Yuye Shi, Yuhao Xue, Chunling Wang & Liang Yu
Pages: 609-619
Published online: 27 May 2022
AbstractforNucleophosmin 1: from its pathogenic role to a tantalizing therapeutic target in acute myeloid leukemia | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Article
Clinical risk factors for patients with myelodysplastic syndromes undergoing allogeneic hematopoietic stem cell transplantation
Haruka Teshigawara-Tanabe, Maki Hagihara, Jun Aoki, Satoshi Koyama, Hiroyuki Takahashi, Yuki Nakajima, Hiroyoshi Kunimoto, Takayoshi Tachibana, Takuya Miyazaki, Kenji Matsumoto, Masatsugu Tanaka, Etsuko Yamazaki, Shin Fujisawa, Heiwa Kanamori, Masataka Taguri & Hideaki Nakajima
Pages: 620-628
Published online: 27 May 2022
AbstractforClinical risk factors for patients with myelodysplastic syndromes undergoing allogeneic hematopoietic stem cell transplantation | Full Text | References | PDF (1.7 MB) | EPUB
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Article
Beyond neurodegenerative diseases: α-synuclein in erythropoiesis
Ling Ling, Fangfang Wang & Duonan Yu
Pages: 629-635
Published online: 27 May 2022
AbstractforBeyond neurodegenerative diseases: α-synuclein in erythropoiesis | Full Text | References | PDF (1.2 MB) | EPUB
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Rapid Communication

Rapid Communication
AML with inv(16)/t(16;16) and high-risk cytogenetic abnormalities: atypical features and unfavorable outcome
Nada Assaf, Christine Lefebvre, Victoria Raggueneau, Geoffroy Guignedoux, Alice Marceau-Renaut, Simon Chevalier, Sylvie Tondeur, Dominique Bories, Riad Benramdane, Philippe Rousselot & Christine Terré
Pages: 636-641
Published online: 27 May 2022
AbstractforAML with inv(16)/t(16;16) and high-risk cytogenetic abnormalities: atypical features and unfavorable outcome | Full Text | References | PDF (621.3 KB) | EPUB
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Research Article

Article
Monoclonal antibodies: new chance in the management of B-cell acute lymphoblastic leukemia
Zheng Shi, Yiqian Zhu, Jing Zhang & Baoan Chen
Pages: 642-652
Published online: 27 May 2022
AbstractforMonoclonal antibodies: new chance in the management of B-cell acute lymphoblastic leukemia | Full Text | References | PDF (875.6 KB) | EPUB
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Article
Prognostic role of controlling nutritional status score in hematological malignancies
Yijing Zhang, Qiuni Chen, Chuanyang Lu & Liang Yu
Pages: 653-658
Published online: 27 May 2022
AbstractforPrognostic role of controlling nutritional status score in hematological malignancies | Full Text | References | PDF (535 KB) | EPUB
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Article
Somatic mutation-associated risk index based on lncRNA expression for predicting prognosis in acute myeloid leukemia
Qiang Xu & Tao Guo
Pages: 659-671
Published online: 06 Jun 2022
AbstractforSomatic mutation-associated risk index based on lncRNA expression for predicting prognosis in acute myeloid leukemia | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
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Article
Prevalence and molecular characterization of common thalassemia among people of reproductive age in the border area of Guangxi-Yunnan-Guizhou province in Southwestern China
GuiDan Xu, ChunFang Wang, JunLi Wang, Min Lin, ZhengYi Chang, JuHua Liang, XiaoHao Chen, ShiMao Zhong, XueJuan Nong, WuJun Wei & YiBin Deng
Pages: 672-683
Published online: 06 Jun 2022
AbstractforPrevalence and molecular characterization of common thalassemia among people of reproductive age in the border area of Guangxi-Yunnan-Guizhou province in Southwestern China | Full Text | References | PDF (2.4 MB) | EPUB
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Case Report

Case Report
Clonal heterogeneity of polymorphic B-cell lymphoproliferative disease, EBV-positive, iatrogenic/immune senescence: implications on pathogenesis and treatment
Yu-Yan Hwang, Rex Au-Yeung, Rock Y.Y. Leung, Eric Tse & Yok-Lam Kwong
Pages: 684-690
Published online: 06 Jun 2022
AbstractforClonal heterogeneity of polymorphic B-cell lymphoproliferative disease, EBV-positive, iatrogenic/immune senescence: implications on pathogenesis and treatment | Full Text | References | PDF (3.1 MB) | EPUB
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Research Article

Article
Infections in relapsed myeloma patients treated with isatuximab plus pomalidomide and dexamethasone during the COVID-19 pandemic: Initial results of a UK-wide real-world study
Faouzi Djebbari, Alexandros Rampotas, Grant Vallance, Fotios Panitsas, Nanda Basker, Gina Sangha, Beena Salhan, Farheen Karim, Al-Kaisi Firas, Amy Gudger, Loretta Ngu, Matt Poynton, Ho Pui Jeff Lam, Lowri Morgan, Laura Yang, Jennifer Young, Mairi Walker, Ismini Tsagkaraki, Laura Anderson, Saleena Rani Chauhan, Rebecca Maddams, Richard Soutar, Margarita Triantafillou, Steve Prideaux, Abubaker Obeidalla, Toby A. Eyre, Ceri Bygrave, Supratik Basu & Karthik Ramasamy
Pages: 691-699
Published online: 06 Jun 2022
AbstractforInfections in relapsed myeloma patients treated with isatuximab plus pomalidomide and dexamethasone during the COVID-19 pandemic: Initial results of a UK-wide real-world study | Full Text | References | PDF (1,003.1 KB) | EPUB
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Article
MiR-140 targets lncRNA FAM230B to suppress cell proliferation in acute myeloid leukemia running title: MiR-140 targets FAM230B in AML
Yan Wang, Fangfang Wang, Yang Lu, Yan Li, Haonan Ran, Feihu Yan & Yuyang Tian
Pages: 700-705
Published online: 06 Jun 2022
AbstractforMiR-140 targets lncRNA FAM230B to suppress cell proliferation in acute myeloid leukemia running title: MiR-140 targets FAM230B in AML | Full Text | References | PDF (1.2 MB) | EPUB
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Article
The prognostic effect on childhood acute lymphoblastic leukemia of CD34+CD38− expressed in leukemia cells
Jiou Zhao, Yun Wang, Min Zhou, Jizhao Gao & Yufang Yuan
Pages: 706-713
Published online: 10 Jun 2022
AbstractforThe prognostic effect on childhood acute lymphoblastic leukemia of CD34+CD38− expressed in leukemia cells | Full Text | References | PDF (1.6 MB) | EPUB
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Article
Outcomes and risk factors of hemorrhagic cystitis in pediatric allogeneic hematopoietic stem cell transplantation recipients using different graft source and condition with severe aplastic anemia
Bohan Li, Lijun Meng, Yuanyuan Tian, Qin Lu, Li Gao, Peifang Xiao, Jun Lu, Jie Li, Lin Wan, Zhiheng Li, Shaoyan Hu & Lingjun Kong
Pages: 714-722
Published online: 10 Jun 2022
AbstractforOutcomes and risk factors of hemorrhagic cystitis in pediatric allogeneic hematopoietic stem cell transplantation recipients using different graft source and condition with severe aplastic anemia | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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Article
Effectiveness and safety of isavuconazole prophylaxis for invasive fungal infections in the haematologic setting
Yang Ping, Jing Hongmei, Christian Bellmann, Mónica Inês, Tom Macmillan, Neil Webb, Jalal A. Aram & Olaf Penack
Pages: 723-732
Published online: 10 Jun 2022
AbstractforEffectiveness and safety of isavuconazole prophylaxis for invasive fungal infections in the haematologic setting | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Article
The efficacy and safety of cyclosporine A plus androgen versus androgen alone for adult patients with non-severe aplastic anemia in China: a meta-analysis of randomized controlled trials
Xiao-tian Zhang, Ya-nan Zhang, Jing-jing Zhu, Xue Wang, Jiang Cao, Wei Chen, Na Qi, Kai-lin Xu & Hai Cheng
Pages: 733-741
Published online: 10 Jun 2022
AbstractforThe efficacy and safety of cyclosporine A plus androgen versus androgen alone for adult patients with non-severe aplastic anemia in China: a meta-analysis of randomized controlled trials | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Letter to the Editor

COVID19 vaccination in adults with sickle cell disease is not associated with increases in rates of pain crisis
Elana Friedman, Caterina Minniti, Sean Campbell & Susanna Curtis
Pages: 742-744
Published online: 20 Jun 2022
AbstractforCOVID19 vaccination in adults with sickle cell disease is not associated with increases in rates of pain crisis | Full Text | References | PDF (311.2 KB) | EPUB
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Research Article

Article
Detection of abnormal lymphocytes in the peripheral blood of COVID-19 cancer patients: diagnostic and prognostic possibility
Lobna Refaat, Mona S. Abdellateif, Ahmed Bayoumi, Medhat Khafagy, Eman Z. Kandeel & Hend A. Nooh
Pages: 745-756
Published online: 20 Jun 2022
AbstractforDetection of abnormal lymphocytes in the peripheral blood of COVID-19 cancer patients: diagnostic and prognostic possibility | Full Text | References | PDF (1.5 MB) | EPUB
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Article
Primary extranodal diffuse large B-cell lymphoma in the rituximab era: a single center, retrospective analysis
Jinrong Zhao, Wei Zhang & Daobin Zhou
Pages: 757-764
Published online: 26 Jun 2022
AbstractforPrimary extranodal diffuse large B-cell lymphoma in the rituximab era: a single center, retrospective analysis | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Genetic mutations associated with blood count abnormalities in myeloid neoplasms
Chantana Polprasert, Sunisa Kongkiatkamon, Pimjai Niparuck, Thanawat Rattanathammethee, Kitsada Wudhikarn, Suporn Chuncharunee, Sirorat Kobbuaklee, Amornchai Suksusut, Theerin Lanamtieng, Panisinee Lawasut, Thiti Asawapanumas, Udomsak Bunworasate & Ponlapat Rojnuckarin
Pages: 765-771
Published online: 29 Jun 2022
AbstractforGenetic mutations associated with blood count abnormalities in myeloid neoplasms | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Case Report

Case Report
A novel mutation Hb jiangnan[β3(NA3) Leu→Lys, HBB:c.10­_11delinsAA] causing elevated Hb A2 level
Liang Liang, Shuting Ning, Xiaocai Lu, Yingwei Li, Mao Tian, Ting Qin & Youqiong Li
Pages: 772-777
Published online: 06 Jul 2022
AbstractforA novel mutation Hb jiangnan[β3(NA3) Leu→Lys, HBB:c.10­_11delinsAA] causing elevated Hb A2 level | Full Text | References | PDF (1.4 MB) | EPUB
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Research Article

Article
The diagnostic and prognostic values of circulating miRNA-1246 in multiple myeloma
Guimin Zhao, Xiaotong Jing, Zheng Li, Xiaolin Wu, Zhe Gao & Ruijuan Ma
Pages: 778-784
Published online: 06 Jul 2022
AbstractforThe diagnostic and prognostic values of circulating miRNA-1246 in multiple myeloma | Full Text | References | PDF (844 KB) | EPUB
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Article
Extracorporeal photopheresis for the treatment of chronic graft versus host disease
Emin Kansu, David Ward, Amber P. Sanchez, Robyn Cunard, Mutlu Hayran, Beril Huseyin, Majella Vaughan, Grace Ku, Peter Curtin, Carolyn Mulroney, Caitlin Costello, Januario E. Castro, Matthew Wieduwilt, Sue Corringham, Anita Ihasz-Davis, Connie Nelson & Edward D. Ball
Pages: 785-794
Published online: 08 Jul 2022
AbstractforExtracorporeal photopheresis for the treatment of chronic graft versus host disease | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Association between serum calcium and in-hospital mortality in critical patients with multiple myeloma: a cohort study
Yafei Mao, Shumin Zhu & Yulan Geng
Pages: 795-801
Published online: 12 Jul 2022
AbstractforAssociation between serum calcium and in-hospital mortality in critical patients with multiple myeloma: a cohort study | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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Article
Phenotypic and genetic analyses of four cases of coagulation factor XII deficiency
Shanshan Li, Kuangyi Shu, Fanfan Li, Xiao Yang, Wei Yang, Manli Ye, Xiaoou Wang & Minghua Jiang
Pages: 802-808
Published online: 22 Jul 2022
AbstractforPhenotypic and genetic analyses of four cases of coagulation factor XII deficiency | Full Text | References | PDF (1.7 MB) | EPUB
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Article
Conducting hematopoietic stem cell transplantation in low and middle income countries
Guillermo J. Ruiz-Argüelles, Adriana Seber & Guillermo J. Ruiz-Delgado
Pages: 809-812
Published online: 27 Jul 2022
AbstractforConducting hematopoietic stem cell transplantation in low and middle income countries | Full Text | References | PDF (495.5 KB) | EPUB
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Article
Prevalence and clinical outcomes of polycythemia vera and essential thrombocythemia with hydroxyurea resistance or intolerance
Kittitat Chiaranairungrot, Komkrich Kaewpreechawat, Chanwit Sajai, Narueporn Pagowong, Nissa Sukarat, Pokpong Piriyakhuntorn, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Adisak Tantiworawit, Lalita Norasetthada & Ekarat Rattarittamrong
Pages: 813-819
Published online: 27 Jul 2022
AbstractforPrevalence and clinical outcomes of polycythemia vera and essential thrombocythemia with hydroxyurea resistance or intolerance | Full Text | References | PDF (693.2 KB) | EPUB
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Article
Role of Tfh17 cells in patients with multiple myeloma
Chunmei Ye, Yuni Xu, Zhenni Wang, Yanxia Chen & Jinlin Liu
Pages: 820-825
Published online: 29 Jul 2022
AbstractforRole of Tfh17 cells in patients with multiple myeloma | Full Text | References | PDF (1,019.1 KB) | EPUB
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Article
The -α3.7III subtype of α+-thalassemia was identified in China
Xiuqin Bao, Jicheng Wang, Danqing Qin, Rui Zhang, Cuize Yao, Jie Liang, Kailing Liang & Li Du
Pages: 826-830
Published online: 02 Aug 2022
AbstractforThe -α3.7III subtype of α+-thalassemia was identified in China | Full Text | References | PDF (960.3 KB) | EPUB
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Rapid Communication

Rapid Communication
Haematology in Latin America
Robert Peter Gale & Gregorio Jaimovich
Pages: 831-832
Published online: 04 Aug 2022
CitationforHaematology in Latin America | Full Text | PDF (342.2 KB) | EPUB
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Research Article

Article
The signature based on seven genomic instability-related genes could predict the prognosis of acute myeloid leukemia patients
Lirong Nie, Yuming Zhang, Yuchan You, Changmei Lin, Qinghua Li, Wenbo Deng, Jingzhi Ma, Wenying Luo & Honghua He
Pages: 833-841
Published online: 04 Aug 2022
AbstractforThe signature based on seven genomic instability-related genes could predict the prognosis of acute myeloid leukemia patients | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Case Report

Case Report
JAK2 V617f in chronic myeloid leukemia: driving force or passive bystander?
Francesco Tarantini, Cosimo Cumbo, Antonella Zagaria, Elisa Parciante, Luisa Anelli, Nicoletta Coccaro, Giuseppina Tota, Crescenzio Francesco Minervini, Immacolata Redavid, Antonella Russo Rossi, Maria Rosa Conserva, Giorgina Specchia, Pellegrino Musto & Francesco Albano
Pages: 842-846
Published online: 08 Aug 2022
AbstractforJAK2 V617f in chronic myeloid leukemia: driving force or passive bystander? | Full Text | References | PDF (819.9 KB) | EPUB | Supplemental
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Research Article

Article
Circulating miR-448 acts as a potential diagnostic biomarker for multiple myeloma
Dan Chen, Teng Chen, Lihong Wang, Zhihua Zhang & Enhong Xing
Pages: 847-852
Published online: 08 Aug 2022
AbstractforCirculating miR-448 acts as a potential diagnostic biomarker for multiple myeloma | Full Text | References | PDF (879.4 KB) | EPUB
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Article
Pairing parents and offspring's HemoTypeSC Test to validate results and confirm sickle cell pedigree:  a case study in Kisangani, the Democratic Republic of the Congo
Emmanuel Tebandite Kasai, Justin Ntokamunda Kadima, Jean Pierre Alworong’a Opara, François Boemer, Marie Françoise Dresse, Julie Makani, Vincent Bours, Roland Marini Djang’eing’a, Kambale-Kombi Paul & Salomon Batina Agasa
Pages: 853-859
Published online: 08 Aug 2022
AbstractforPairing parents and offspring's HemoTypeSC Test to validate results and confirm sickle cell pedigree:  a case study in Kisangani, the Democratic Republic of the Congo | Full Text | References | PDF (986.1 KB) | EPUB
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Article
Contributions of von Willebrand factor to clinical severity of sickle cell disease: a systematic review and metanalysis
T. U. Nwagha, Martins Nweke & E. D. Ezigbo
Pages: 860-866
Published online: 08 Aug 2022
AbstractforContributions of von Willebrand factor to clinical severity of sickle cell disease: a systematic review and metanalysis | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Article
First study to describe a novel HbA2: c.400A > C mutation and Hb Dongguan heterozygote in two unrelated Chinese families
Cuize Yao, Danqing Qin, Jicheng Wang, Xiuqin Bao, Jie Liang & Li Du
Pages: 867-873
Published online: 08 Aug 2022
AbstractforFirst study to describe a novel HbA2: c.400A > C mutation and Hb Dongguan heterozygote in two unrelated Chinese families | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Analysis of clinical characteristics and prognostic factors associated with EBV-associated HLH in children
Kun-yin Qiu, Shu-yi Guo, Yang-hui Zeng, Xiong-yu Liao, Shao-fen Lin, Jian-pei Fang & Dun-hua Zhou
Pages: 874-880
Published online: 11 Aug 2022
AbstractforAnalysis of clinical characteristics and prognostic factors associated with EBV-associated HLH in children | Full Text | References | PDF (708.6 KB) | EPUB | Supplemental
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Article
Trends in prevalence and treatment rate of anemia in the U.S. population: cross-sectional study using data from NHANES 2005–2018
Chen Wang & Yan Wang
Pages: 881-888
Published online: 12 Aug 2022
AbstractforTrends in prevalence and treatment rate of anemia in the U.S. population: cross-sectional study using data from NHANES 2005–2018 | Full Text | References | PDF (1 MB) | EPUB
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Article
Prevalence of elevated hemoglobin and hematocrit levels in patients with obstructive sleep apnea and the impact of treatment with continuous positive airway pressure: a meta-analysis
Vanessa Martelli, Eric Carelli, George A. Tomlinson, Ani Orchanian-Cheff, Kevin H. M. Kuo, Owen D. Lyons & Clodagh M. Ryan
Pages: 889-901
Published online: 12 Aug 2022
AbstractforPrevalence of elevated hemoglobin and hematocrit levels in patients with obstructive sleep apnea and the impact of treatment with continuous positive airway pressure: a meta-analysis | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
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Article
The different variant allele frequencies of type I/type II mutations and the distinct molecular landscapes in CALR-mutant essential thrombocythaemia and primary myelofibrosis
Yuxia Pan, Xingzhe Wang, Shupeng Wen, Xiaojun Liu, Lin Yang & Jianmin Luo
Pages: 902-908
Published online: 24 Aug 2022
AbstractforThe different variant allele frequencies of type I/type II mutations and the distinct molecular landscapes in CALR-mutant essential thrombocythaemia and primary myelofibrosis | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Lymphoma-associated hemophagocytic syndrome: a retrospective study from a single center
Na Li, Ming Jiang, Wan-chun Wu, Hui-jie Zhou & Li-qun Zou
Pages: 909-916
Published online: 20 Aug 2022
AbstractforLymphoma-associated hemophagocytic syndrome: a retrospective study from a single center | Full Text | References | PDF (889.3 KB) | EPUB
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Article
Efficacy and safety of blinatumomab in Chinese adults with Ph-negative relapsed/refractory B-cell precursor acute lymphoblastic leukemia: A multicenter open-label single-arm China registrational study
Hongsheng Zhou, Qingsong Yin, Jie Jin, Ting Liu, Zhen Cai, Bin Jiang, Dengju Li, Zimin Sun, Yan Li, Yanjuan He, Liping Ma, Sujun Gao, Jianda Hu, Aili He, Xin Du, Daihong Liu, Xiaohong Zhang, Xiaoyan Ke, Junling Zhuang, Yue Han, Xiaoqin Wang, Yuqi Chen, Paul Gordon, Dong Yu, Gerhard Zugmaier & Jianxiang Wang
Pages: 917-927
Published online: 24 Aug 2022
AbstractforEfficacy and safety of blinatumomab in Chinese adults with Ph-negative relapsed/refractory B-cell precursor acute lymphoblastic leukemia: A multicenter open-label single-arm China registrational study | Full Text | References | PDF (1.5 MB) | EPUB
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Article
Multiple myeloma in Latin America
David Gómez-Almaguer & Vânia Tietsche de Moraes Hungria
Pages: 928-931
Published online: 24 Aug 2022
AbstractforMultiple myeloma in Latin America | Full Text | References | PDF (487.3 KB) | EPUB
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Article
A mouse model of irradiation and spleen-thymus lymphocyte infusion induced aplastic anemia
Runfeng Ni, Liwei Fan, Le Zhang, Yanqi Song, Haijin Wang, Aidi Wang & Baoshan Liu
Pages: 932-945
Published online: 25 Aug 2022
AbstractforA mouse model of irradiation and spleen-thymus lymphocyte infusion induced aplastic anemia | Full Text | References | PDF (5.3 MB) | EPUB
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Case Report

Case Report
Identification of a rare compound heterozygous hemoglobin variant β0-thal [β17(A14) Lys>Stop, HBB: c.52A>T] and Hb J-Lome [β59(E3) Lys>Asn, HBB: c.180G>C]
Zixin Chen, Limei Shao, Mingfeng Jiang, Run Ma, Hongfen Ping, Zhuo Wang, Xuejiao Ba, Bingjie Ma & Tao Zhou
Pages: 946-950
Published online: 25 Aug 2022
AbstractforIdentification of a rare compound heterozygous hemoglobin variant β0-thal [β17(A14) Lys>Stop, HBB: c.52A>T] and Hb J-Lome [β59(E3) Lys>Asn, HBB: c.180G>C] | Full Text | References | PDF (1.2 MB) | EPUB
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Research Article

Article
Circ_0003489 facilitates multiple myeloma progression by targeting miR-433-3p/PBX3 axis
Tielun Yan, Xiaoli Wang, Dajin Zhou, Haibo Qiu, Jiliang Zhang & Weixiong Yang
Pages: 951-959
Published online: 25 Aug 2022
AbstractforCirc_0003489 facilitates multiple myeloma progression by targeting miR-433-3p/PBX3 axis | Full Text | References | PDF (3.1 MB) | EPUB
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Article
Hsa_circ_0044907 promotes acute myeloid leukemia progression through upregulating oncogene KIT via sequestering miR-186-5p
Ling Liu & Xing Qiang
Pages: 960-970
Published online: 25 Aug 2022
AbstractforHsa_circ_0044907 promotes acute myeloid leukemia progression through upregulating oncogene KIT via sequestering miR-186-5p | Full Text | References | PDF (2.9 MB) | EPUB
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Article
Diagnosis and treatment of acute lymphoblastic leukemia in Latin America
Perla R. Colunga-Pedraza, Julia E. Colunga-Pedraza, Samantha P. Peña-Lozano, Andrés Gómez-De León, Guillermo J. Ruiz-Delgado & Raul C. Ribeiro
Pages: 971-976
Published online: 30 Aug 2022
AbstractforDiagnosis and treatment of acute lymphoblastic leukemia in Latin America | Full Text | References | PDF (1 MB) | EPUB
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Article
Formosanin C induces autophagy-mediated apoptosis in multiple myeloma cells through the PI3K/AKT/mTOR signaling pathway
Ping Chen, Sungui Wu, Xiaoqing Dong, Min Zhou, Peipei Xu & Bing Chen
Pages: 977-986
Published online: 02 Sep 2022
AbstractforFormosanin C induces autophagy-mediated apoptosis in multiple myeloma cells through the PI3K/AKT/mTOR signaling pathway | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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Article
Cancer and nutrition among children and adolescents in low- and middle-income countries
Ronald D. Barr & Federico Antillon-Klussmann
Pages: 987-993
Published online: 12 Sep 2022
AbstractforCancer and nutrition among children and adolescents in low- and middle-income countries | Full Text | References | PDF (901.5 KB) | EPUB
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Article
Frequency and clinical impact of WT1 mutations in the context of CEBPA-mutated acute myeloid leukemia
Ting Wang, Haiying Hua, Zheng Wang, Biao Wang, Liujun Cao, Wei Qin, Pin Wu, Xiaohui Cai, Hongying Chao & XuZhang Lu
Pages: 994-1002
Published online: 06 Sep 2022
AbstractforFrequency and clinical impact of WT1 mutations in the context of CEBPA-mutated acute myeloid leukemia | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Decreased expression of HBA1 and HBB genes in acute myeloid leukemia patients and their inhibitory effects on growth of K562 cells
Ping Luo, Xiaoyan Liu, Zehai Tang & Bei Xiong
Pages: 1003-1009
Published online: 17 Sep 2022
AbstractforDecreased expression of HBA1 and HBB genes in acute myeloid leukemia patients and their inhibitory effects on growth of K562 cells | Full Text | References | PDF (1.2 MB) | EPUB
  • 1682 Views
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Article
Myeloid neoplasm with ETV6::ACSl6 fusion: landscape of molecular and clinical features
Zhan Su, Xin Liu, Weiyu Hu, Jie Yang, Xiangcong Yin, Fang Hou, Yaqi Wang & Jinglian Zhang
Pages: 1010-1018
Published online: 07 Sep 2022
AbstractforMyeloid neoplasm with ETV6::ACSl6 fusion: landscape of molecular and clinical features | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Characteristic features of primary testicular lymphoma and survival trends: a multicenter clinical study
Yujiao Sun, Xueshen Yan, Hongguo Zhao, Zhongguang Cui, Yayun Wang, Shuxiang Sun, Xiaohan Ning & Hong Xu
Pages: 1019-1025
Published online: 06 Sep 2022
AbstractforCharacteristic features of primary testicular lymphoma and survival trends: a multicenter clinical study | Full Text | References | PDF (1.3 MB) | EPUB
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Article
The population incidence of thalassemia gene variants in Baise, Guangxi, P. R. China, based on random samples
Bixiao Wei, Weijie Zhou, Mingkui Peng, Ju Long & Wangrong Wen
Pages: 1026-1031
Published online: 06 Sep 2022
AbstractforThe population incidence of thalassemia gene variants in Baise, Guangxi, P. R. China, based on random samples | Full Text | References | PDF (653.1 KB) | EPUB
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Article
Tyrosine kinase inhibitors and reduced-dose chemotherapy for adult Philadelphia chromosome-positive acute lymphoblastic leukemia
Chunping Wu, Mengting Zeng, Yuanzhong Chen & Yong Wu
Pages: 1032-1040
Published online: 09 Sep 2022
AbstractforTyrosine kinase inhibitors and reduced-dose chemotherapy for adult Philadelphia chromosome-positive acute lymphoblastic leukemia | Full Text | References | PDF (1.5 MB) | EPUB
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Case Report

Case Report
Severe immunochemotherapy-induced toxicities in a patient with dyskeratosis congenita and literature review
Jiayi Geng, Menglin Zhao & Qiuyu Li
Pages: 1041-1045
Published online: 08 Sep 2022
AbstractforSevere immunochemotherapy-induced toxicities in a patient with dyskeratosis congenita and literature review | Full Text | References | PDF (759.9 KB) | EPUB
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Research Article

Article
CircNFIX knockdown inhibited AML tumorigenicity by the miR-876-3p/TRIM31 axis
Lifang Huang, Liang Huang, Xi Ming, Jiaying Wu, Wanying Liu & Yi Xiao
Pages: 1046-1055
Published online: 12 Sep 2022
AbstractforCircNFIX knockdown inhibited AML tumorigenicity by the miR-876-3p/TRIM31 axis | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
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Article
Genetic polymorphism of clopidogrel metabolism related gene CYP2C19 gene in Chinese from Foshan area of Guangdong Province
Xiao-wen Yuan, Shi-yun Yuan, Guo-xin Wu, zhi-xin Wu & Zi-yun Guan
Pages: 1056-1061
Published online: 16 Sep 2022
AbstractforGenetic polymorphism of clopidogrel metabolism related gene CYP2C19 gene in Chinese from Foshan area of Guangdong Province | Full Text | References | PDF (812.6 KB) | EPUB
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Article
Clinical efficacy of recombinant human thrombopoietin combined with glucocorticoids in the treatment of immune thrombocytopenia
Jing-xin Zhou, Ling Gao, Nan Hu, Zhi-Ling Yan, Chun-ying Tian, Jing Su, Ji-Jin Qi, Jun-shuai Yue & Wen-tong Ma
Pages: 1062-1068
Published online: 12 Sep 2022
AbstractforClinical efficacy of recombinant human thrombopoietin combined with glucocorticoids in the treatment of immune thrombocytopenia | Full Text | References | PDF (931 KB) | EPUB
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Article
Efficacy of maintenance treatment in patients with multiple myeloma: a systematic review and network meta-analysis
Yongjin Zhi, Shuojing Bao, Jingcheng Mao, Gufan Chai, Jianfeng Zhu, Chengjiang Liu & Xi Chen
Pages: 1069-1088
Published online: 20 Sep 2022
AbstractforEfficacy of maintenance treatment in patients with multiple myeloma: a systematic review and network meta-analysis | Full Text | References | PDF (3.1 MB) | EPUB
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Article
An immune-related gene prognostic index for acute myeloid leukemia associated with regulatory T cells infiltration
Qiongni Xie, Zhongyuan Tang, Xiaolin Liang, Zeyan Shi, Yibin Yao, Xiaoke Huang, Shanhu Zhu, Meiqing Wu, Jing Li, Weihua Zhao & Zhenfang Liu
Pages: 1089-1101
Published online: 14 Sep 2022
AbstractforAn immune-related gene prognostic index for acute myeloid leukemia associated with regulatory T cells infiltration | Full Text | References | PDF (3.3 MB) | EPUB
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Article
Spliced X-Box binding protein 1 predicts satisfying responsiveness and survival benefit toward bortezomib-based therapy in multiple myeloma patients
Lingli Zhang, Jichang Gong & Li Yaqiong
Pages: 1102-1109
Published online: 19 Sep 2022
AbstractforSpliced X-Box binding protein 1 predicts satisfying responsiveness and survival benefit toward bortezomib-based therapy in multiple myeloma patients | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Mechanism of immunomodulatory drug resistance and novel therapeutic strategies in multiple myeloma
Xiaojia Zuo & Dingsheng Liu
Pages: 1110-1121
Published online: 19 Sep 2022
AbstractforMechanism of immunomodulatory drug resistance and novel therapeutic strategies in multiple myeloma | Full Text | References | PDF (1.3 MB) | EPUB
  • 2404 Views
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Article
Expression and clinical significance of RAG1 in myelodysplastic syndromes
Xiaoke Huang, Xiaolin Liang, Shanhu Zhu, Qiongni Xie, Yibin Yao, Zeyan Shi & Zhenfang Liu
Pages: 1122-1129
Published online: 27 Sep 2022
AbstractforExpression and clinical significance of RAG1 in myelodysplastic syndromes | Full Text | References | PDF (1.3 MB) | EPUB
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Article
The role of serum-free light chain ratios in the prediction of poor prognosis in multiple myeloma patients: a systematic review and meta-analysis
Dan Cao, Lihong Shou, Ying Wu & Xiaohui Dong
Pages: 1130-1139
Published online: 27 Sep 2022
AbstractforThe role of serum-free light chain ratios in the prediction of poor prognosis in multiple myeloma patients: a systematic review and meta-analysis | Full Text | References | PDF (1.7 MB) | EPUB
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Article
The burden of illness of patients with paroxysmal nocturnal haemoglobinuria receiving C5 inhibitors: clinical outcomes and medical encounters from the patient perspective
Flore Sicre de Fontbrune, Pascale Burmester, Maria Piggin, Joana E. Matos, Halley Costantino, Koo Wilson, Zalmai Hakimi, Jameel Nazir, Renaud Desgraz, Jesse Fishman, Emmelie Persson & Jens Panse
Pages: 1140-1151
Published online: 27 Sep 2022
AbstractforThe burden of illness of patients with paroxysmal nocturnal haemoglobinuria receiving C5 inhibitors: clinical outcomes and medical encounters from the patient perspective | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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Article
MicroRNA-92a-3p-mediated inhibition of BCL11A upregulates γ-globin expression and inhibits oxidative stress and apoptosis in erythroid precursor cells
Huili Li, Ruoping Lin, Huan Li, Rilan Ou, Kaiping Wang, Junrong Lin & Chunfu Li
Pages: 1152-1162
Published online: 30 Sep 2022
AbstractforMicroRNA-92a-3p-mediated inhibition of BCL11A upregulates γ-globin expression and inhibits oxidative stress and apoptosis in erythroid precursor cells | Full Text | References | PDF (2.3 MB) | EPUB
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Article
From iron chelation to overload as a therapeutic strategy to induce ferroptosis in hematologic malignancies
Jiaojiao Li & Wei Zhang
Pages: 1163-1170
Published online: 12 Oct 2022
AbstractforFrom iron chelation to overload as a therapeutic strategy to induce ferroptosis in hematologic malignancies | Full Text | References | PDF (1,010.4 KB) | EPUB
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Case Report

Case Report
Higher neutrophil counts are associated with successful tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia
Hiroshi Ureshino, Kazuharu Kamachi, Haruhiko Sano, Sho Okamoto, Hidekazu Itamura, Mariko Yoshimura, Hiroo Katsuya, Toshihiko Ando & Shinya Kimura
Pages: 1171-1175
Published online: 03 Nov 2022
AbstractforHigher neutrophil counts are associated with successful tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia | Full Text | References | PDF (1.2 MB) | EPUB
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Research Article

Article
Blood MALT1 deficiency is common and relates to unfavorable induction therapy response and survival profile in acute myeloid leukemia patients
Haili Geng, Yiting Wang & Shaoyuan Wang
Pages: 1176-1183
Published online: 31 Oct 2022
AbstractforBlood MALT1 deficiency is common and relates to unfavorable induction therapy response and survival profile in acute myeloid leukemia patients | Full Text | References | PDF (1.5 MB) | EPUB
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Article
Clinical characteristics and prognostic analysis of acute myeloid leukemia patients with PTPN11 mutations
Yueyue Sun, Fenghong Zhang, Li Huo, Wenzhi Cai, Qinrong Wang, Lijun Wen, Lingzhi Yan, Hongjie Shen, Xiaoyu Xu & Suning Chen
Pages: 1184-1190
Published online: 01 Nov 2022
AbstractforClinical characteristics and prognostic analysis of acute myeloid leukemia patients with PTPN11 mutations | Full Text | References | PDF (1.1 MB) | EPUB
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Case Report

Case Report
Very severe immune aplastic anemia after mRNA vaccination against COVID-19 responds well to immunosuppressive therapy: clinical characteristics and comparison to previous reports
Suhyeon Woo, Bohyun Kim, Sang-Cheol Lee, Min-Sun Kim, Young Ahn Yoon & Young-Jin Choi
Pages: 1191-1195
Published online: 31 Oct 2022
AbstractforVery severe immune aplastic anemia after mRNA vaccination against COVID-19 responds well to immunosuppressive therapy: clinical characteristics and comparison to previous reports | Full Text | References | PDF (1.3 MB) | EPUB
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Research Article

Article
Blockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion
Jianhui Xu, Jingwen Du, Yuxia Zhong, Honghao Zhang, Lijuan Zhou & Qianqian Yao
Pages: 1196-1203
Published online: 03 Nov 2022
AbstractforBlockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion | Full Text | References | PDF (1.1 MB) | EPUB
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Case Report

Case Report
A case of Hb Rothschild (HBB: c.112T>A) with low pulse oximetry: a first familial presentation in China
Diandian Li, Qunfang Wan, Chunyu Li, Hongbing Ma & Gang Wang
Pages: 1204-1207
Published online: 04 Nov 2022
AbstractforA case of Hb Rothschild (HBB: c.112T>A) with low pulse oximetry: a first familial presentation in China | Full Text | References | PDF (868.9 KB) | EPUB
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Research Article

Article
Non-Hodgkin lymphoma treatment in middle-income countries in Latin America: perspective of the Latin American Study Group of Lymphoproliferative Disorders [Grupo de Estudio de Linfoproliferativos de Latino América (GELL)]
Luis Villela, María Torre-Viera, Henry Idrobo-Quintero, Brady E. Beltran & on behalf of Grupo de Estudio de Linfoproliferativos de Latinoamérica (GELL)
Pages: 1208-1216
Published online: 03 Nov 2022
AbstractforNon-Hodgkin lymphoma treatment in middle-income countries in Latin America: perspective of the Latin American Study Group of Lymphoproliferative Disorders [Grupo de Estudio de Linfoproliferativos de Latino América (GELL)] | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Efficacy and safety of plasmapheresis without plasma transfusion tandem with chemotherapy to treat multiple myeloma
Yigang Guo, Lulu Zhang, Rongyao Zhang, Meiling Zhou, Xu Chen, Chucheng Wan, Ping Hu, Yuanyuan He, Hua Jiang, Wei Geng, Weixing Zhang, Fariha Kanwal, Muhammad Fayyaz ur Rehman & Zhangzhi Li
Pages: 1217-1222
Published online: 11 Nov 2022
AbstractforEfficacy and safety of plasmapheresis without plasma transfusion tandem with chemotherapy to treat multiple myeloma | Full Text | References | PDF (642.6 KB) | EPUB
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Article
Survival and response deepening after autologous transplantation in patients with multiple myeloma in Chile
María Carolina Guerra, Joaquín Jerez, Giselle Godoy, José Luis Briones, Carlos Torres, Sebastián Hidalgo, Valentina Goldschmidt & Raimundo Gazitúa
Pages: 1223-1229
Published online: 10 Nov 2022
AbstractforSurvival and response deepening after autologous transplantation in patients with multiple myeloma in Chile | Full Text | References | PDF (929.7 KB) | EPUB
  • 886 Views
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Lunhui Huang, Guoqing Zhu, Yueyi Mu & Yonghui Xia
Pages: 1230-1236
Published online: 14 Nov 2022
AbstractforThe Sysmex XN series hematopoietic progenitor cell (XN-HPC) as a predictive marker of stem cell enumeration and products: a systemic review and meta-analysis | Full Text | References | PDF (1.1 MB) | EPUB
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Pages: 1237-1245
Published online: 22 Nov 2022
AbstractforExternal validation and comparison of IPI, R-IPI, and NCCN-IPI in diffuse large B-cell lymphoma patients treated with R-CHOP to predict 2-year progression-free survival | Full Text | References | PDF (2.3 MB) | EPUB
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Xiaolin Liang, Zeyan Shi, Xiaoke Huang, Chengyao Wan, Shanhu Zhu, Meiqing Wu, Zhongqing Li, Zhongyuan Tang, Jing Li, Weihua Zhao, Jun Luo & Zhenfang Liu
Pages: 1246-1252
Published online: 29 Nov 2022
AbstractforMiR-181a-2-3p as a potential diagnostic and prognostic marker for myelodysplastic syndrome | Full Text | References | PDF (926.8 KB) | EPUB
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Case Report

Case Report
Dapsone-induced methemoglobinemia and hemolysis in a woman without G6PD deficiency presenting with idiopathic urticaria
Yang Hu, Mimansa Geere, Maham Awan, Andrew D. Leavitt, Laura E. Brown, Hadley J. Pearson, Jocelyn S. Gandelman & Scott C. Kogan
Pages: 1253-1258
Published online: 29 Nov 2022
AbstractforDapsone-induced methemoglobinemia and hemolysis in a woman without G6PD deficiency presenting with idiopathic urticaria | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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Case Report
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Pages: 1259-1262
Published online: 30 Nov 2022
AbstractforDe novo lymphoid blastic phase chronic myeloid leukemia: report and contemporary discussion | Full Text | References | PDF (559.2 KB) | EPUB
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Research Article

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Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy
Lu Zhang, Shufang Wei, Jiajia Li, Pengming Wang & Ge Yinghui
Pages: 1263-1271
Published online: 06 Dec 2022
AbstractforValue of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy | Full Text | References | PDF (1.3 MB) | EPUB
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Clinical prognostic risk analysis and progression factor exploration of primary breast lymphoma
Jili Deng, Lan Mi, Xiaopei Wang, Jun Zhu, Chen Zhang & Yuqin Song
Pages: 1272-1281
Published online: 07 Dec 2022
AbstractforClinical prognostic risk analysis and progression factor exploration of primary breast lymphoma | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
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Progress on the efficacy and potential mechanisms of rapamycin in the treatment of immune thrombocytopenia
Dan Wang, Kaniel Cassady, Zhongmin Zou, Xi Zhang & Yimei Feng
Pages: 1282-1289
Published online: 05 Dec 2022
AbstractforProgress on the efficacy and potential mechanisms of rapamycin in the treatment of immune thrombocytopenia | Full Text | References | PDF (819 KB) | EPUB
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Case Report

Case Report
Clinical characteristics of a patient with de novo acute promyelocytic leukemia with JAK2 v617f mutation
Yi-zhi Jiang, Zhong-ling Wei, Na-na Wang, Chen Huang, Jun Huang, Jia-wei Yan, Ran Wang, Zheng-zhi Yu & Dong-ping Huang
Pages: 1290-1293
Published online: 07 Dec 2022
AbstractforClinical characteristics of a patient with de novo acute promyelocytic leukemia with JAK2 v617f mutation | Full Text | References | PDF (907.9 KB) | EPUB
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Research Article

Article
Hematopoietic stem cell transplantation activity in Mexico during the COVID19 pandemic: on the way to recovery
Andrés Gómez-De León, Lourdes Gil-Flores, Perla Colunga-Pedraza, Christianne Bourlon, César Vargas-Serafín, María de los Ángeles del Campo-Martínez, Alberto Olaya-Vargas, Martín Pérez-García, Xitlaly J. González-Leal, Miguel Angel Herrera Rojas, Sergio Lozano-Rodríguez, Manuel Solano-Genesta, Anna Cecilia Rodríguez-Zúñiga, Alexia Sánchez-Arteaga, Guillermo J. Ruiz-Argüelles, David Gómez-Almaguer & on Behalf of the Transplantation and Cellular Therapy Working Group in Mexico (TCTMX)
Pages: 1294-1300
Published online: 14 Dec 2022
AbstractforHematopoietic stem cell transplantation activity in Mexico during the COVID19 pandemic: on the way to recovery | Full Text | References | PDF (2 MB) | EPUB | Supplemental
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Letter to the Editor

Comparison of Molecular International Prognostic Scoring System (M-IPSS) and Revised International Prognostic Scoring System (R-IPSS) in Thai patients with myelodysplastic neoplasms
Chantana Polprasert, Pimjai Niparuck, Thanawat Rattanathammethee, Sirorat Kobbuaklee, Theerin Lanamtieng & Ponlapat Rojnuckarin
Pages: 1301-1304
Published online: 15 Dec 2022
AbstractforComparison of Molecular International Prognostic Scoring System (M-IPSS) and Revised International Prognostic Scoring System (R-IPSS) in Thai patients with myelodysplastic neoplasms | Full Text | References | PDF (1,013.1 KB) | EPUB | Supplemental
  • 979 Views
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Research Article

Article
Application of third-generation sequencing for genetic testing of thalassemia in Guizhou Province, Southwest China
Jiangfen Wu, Dan Xie, Lei Wang, Ying Kuang, Shulin Luo, Lingyan Ren, Di Li, Aiping Mao, Jiaqi Li, Libao Chen, Bangquan An & Shengwen Huang
Pages: 1305-1311
Published online: 15 Dec 2022
AbstractforApplication of third-generation sequencing for genetic testing of thalassemia in Guizhou Province, Southwest China | Full Text | References | PDF (906.2 KB) | EPUB
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