Figures & data
Table 1. Phosphorylation sites identified in the mouse brain Cav2.3 α1-subunit (Q61290) [Citation71]. The GenBank entry Q61290 mentions only part of the sites, which were originally listed as in vivo identified phosphopeptides (labelled in bold). In addition, this so called large scale analysis identified residue Ser-816 in the II-III loop as an additional phosphorylation site.
Figure 1. Location of predicted phosphorylation sites within human Cav2.3d. (a). Cartoon of the deduced transmembrane organization of the human Cav2.3d subunit. (b). Predicted phosphorylation sites within the amino terminus, the I-II loop and the II-III loop. (c). and (d). Predicted phosphorylation sites within the carboxy terminus including a cluster of putative phosphorylation sites for PKC, PKA and tyrosine kinase downstream of important functional domains (EF-like and IQ site as well as the inserted exon 45 of the splice variant d of Cav2.3). (E). A detailed view of the alternate exons 19 and 45, which are identified in different Cav2.3 splice variants (for details see 53) is shown. Note within exon 45 one additional PKC site, which was predicted.
