Figures & data
Figure 1. Fast loss and gain of consciousness after exposure and removal of anesthetics is based on primary processes linked to the plasma membrane (ion fluxes, electric activities, endocytic vesicle recycling), whereas changes in gene expression are playing only secondary roles.
Figure 2. Both in animals and plants, organs with the highest activities of endocytic vesicle recycling and electric activities are implied in loss of consciousness (motility, sensitivity, and behavior).
Figure 3. Claude Bernard discovered higher sensitivity of photosynthesis to anesthetics in comparison to respiration.Citation12,25 Chloroplast accomplish photosynthesis on stacked membranes know as thylakoid granaCitation162,163 which can be considered for inter-organellar synapses.Citation157 We propose that these stacked membranes are not only essential for photosynthesis but also makes this process more sensitive to anesthetics.
