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Articles

Increased urinary excretion of aluminium after ingestion of the food additive sodium aluminium phosphate (SALP) – a study on healthy volunteers

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Pages 1236-1243 | Received 15 Jan 2019, Accepted 26 May 2019, Published online: 13 Jun 2019

Figures & data

Figure 1. Experimental design. Baseline urine sampling for Al analyses took place in the morning before the start of the 7-day ingestion of pancakes and antacid. Test sampling of urine took place directly after the last ingestion of pancakes and antacid in the morning of the 7th day of ingestion.

Figure 1. Experimental design. Baseline urine sampling for Al analyses took place in the morning before the start of the 7-day ingestion of pancakes and antacid. Test sampling of urine took place directly after the last ingestion of pancakes and antacid in the morning of the 7th day of ingestion.

Figure 2. Al concentrations (median, max) in spot urine samples of 18 healthy volunteers. Samples were taken before and after consumption pancakes with no Al additive, pancakes with the Al additive SALP, and an Al-containing antacid for 7 days. Baseline sample 1 was taken in the morning before the start of no Al pancake ingestion. Baseline sample 2 was taken at least 7 days after the end of ingestion of no Al pancakes, in the morning before start of ingestion of pancakes with Al (SALP). Baseline 3 sample was taken after a rest period of at least 7 days, in the morning before start of ingestion of Al-containing antacid. Test samples were taken in the morning directly after the last ingestion of no Al pancakes, Al pancakes and antacid during the test period. *p ≤ 0.05, between baseline 2 and Al pancake samplings, and between baseline 3 and Al antacid samplings (Mann-Whitney U test, N = 18).

Figure 2. Al concentrations (median, max) in spot urine samples of 18 healthy volunteers. Samples were taken before and after consumption pancakes with no Al additive, pancakes with the Al additive SALP, and an Al-containing antacid for 7 days. Baseline sample 1 was taken in the morning before the start of no Al pancake ingestion. Baseline sample 2 was taken at least 7 days after the end of ingestion of no Al pancakes, in the morning before start of ingestion of pancakes with Al (SALP). Baseline 3 sample was taken after a rest period of at least 7 days, in the morning before start of ingestion of Al-containing antacid. Test samples were taken in the morning directly after the last ingestion of no Al pancakes, Al pancakes and antacid during the test period. *p ≤ 0.05, between baseline 2 and Al pancake samplings, and between baseline 3 and Al antacid samplings (Mann-Whitney U test, N = 18).