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Review

A review of mechanistic models of viral dynamics in bat reservoirs for zoonotic disease

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Figures & data

Table 1. All published mechanistic models of virus dynamics in bat systems (2007–2020)

Table 2. Summary of data-fitted models investigating virus transmission dynamics

Figure 1. Distribution of bat virus modeling studies to date.

Shading hue indicates the number of bat virus modeling studies conducted to date. Colored pie-charts indicate each model’s approach to data (by percentage) for each locality, whether purely theoretical, simulated using data-derived parameters, or explicitly fitted to data. For theoretical models that did not specify a distinct locality, the continent (i.e. Africa) is shaded instead.
Figure 1. Distribution of bat virus modeling studies to date.

Figure 2. Trends in mechanistic modeling of bat-virus systems.

Histogram of timeline of publication for mechanistic models of bat-virus systems, organized by (a) Locality of focal study site, (b) Taxonomy of virus studied, and (c) Approach to data, as shown in .
Figure 2. Trends in mechanistic modeling of bat-virus systems.

Figure 3. Universal compartmental model structure for models fitted to data.

Compartmental model structure of each viral taxonomic group: (a) Lyssaviruses, (b) Filoviruses, (c) Henipaviruses, and (d) Coronaviruses. For lyssaviruses, structure is shown separately for rabies (RABV), European bat lyssavirus-1 (EBLV-1), and Lagos bat virus (LBV). For all diagrams, universal pathways are depicted in black, and those unique to a specific published model are depicted in color. Each parameter’s status (fitted or drawn from the literature) is indicated adjacent to the author by the font face (bold or italicized) of the text. Age-structure and metapopulation dynamics are not depicted in the compartmental diagrams depicted here, but parameters specific to these more complex dynamics are listed adjacent to the author with an asterisk.*
Figure 3. Universal compartmental model structure for models fitted to data.
Supplemental material

Supplemental Material

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