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Letters to Editor

Coexistence of two novel resistance plasmids, blaKPC-2-carrying p14057A and tetA(A) -carrying p14057B, in Pseudomonas aeruginosa

, , , , , , , , , , , , & show all
Pages 306-311 | Received 06 Jul 2017, Accepted 22 Aug 2017, Published online: 04 Oct 2017

Figures & data

Figure 1. Schematic map of p14057A and p14057B. Genes are denoted by arrows, and the backbone and accessory module regions are highlighted in black and color, respectively. The innermost circle presents GC-skew [(G-C)/(G+C)], with a window size of 500 bp and a step size of 20 bp. The next-to-innermost circle presents GC content. Shown also are backbone and accessory modules.

Figure 1. Schematic map of p14057A and p14057B. Genes are denoted by arrows, and the backbone and accessory module regions are highlighted in black and color, respectively. The innermost circle presents GC-skew [(G-C)/(G+C)], with a window size of 500 bp and a step size of 20 bp. The next-to-innermost circle presents GC content. Shown also are backbone and accessory modules.

Figure 2. The accessory regions of p14057A and p14057B and comparison to related genetic contents. Genes are denoted by arrows. Genes, mobile elements and other features are colored based on function classification. Shading denotes regions of homology (>95% nucleotide identity). Numbers in brackets indicate the nucleotide positions within the corresponding plasmids. The accession numbers of Tn1721, Tn3, Tn6296, and Tn1403 for reference are X61367, HM749966, FJ628167, and AF313472, respectively.

Figure 2. The accessory regions of p14057A and p14057B and comparison to related genetic contents. Genes are denoted by arrows. Genes, mobile elements and other features are colored based on function classification. Shading denotes regions of homology (>95% nucleotide identity). Numbers in brackets indicate the nucleotide positions within the corresponding plasmids. The accession numbers of Tn1721, Tn3, Tn6296, and Tn1403 for reference are X61367, HM749966, FJ628167, and AF313472, respectively.

Table 1. Antimicrobial drug susceptibility profiles.