Figures & data
Figure 1. Strategies for the ex vivo generation of early memory tumor-reactive T cells for adoptive immunotherapy. Generation of early memory tumor-reactive T cells via different strategies. (A, B) T-cell receptor (TCR) transfer in the presence of Wnt signaling, or interleukin (IL)-7 and IL-15 stimulation. (C) Expansion of naive T-cell progenitors using dendritic cells in the presence of an Akt-inhibitor (Akt-inh). (D) Expansion of tumor-infiltrating lymphocytes (TILs) in the presence of an Akt-inhibitor.
