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OncoImmunology Volume 5, 2016 - Issue 6
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DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma

Jie JiDepartment of Photomedicine, Shanghai Skin Disease Hospital, Shanghai, China
,
Yunfeng ZhangDepartment of Photomedicine, Shanghai Skin Disease Hospital, Shanghai, China
,
Wei R. ChenDepartment of Photomedicine, Shanghai Skin Disease Hospital, Shanghai, China;Biophotonics Research Laboratory, Center for Interdisciplinary Biomedical Education and Research, University of Central Oklahoma, Edmond, OK, USACorrespondence[email protected] [email protected]
&
Xiuli WangDepartment of Photomedicine, Shanghai Skin Disease Hospital, Shanghai, ChinaCorrespondence[email protected] [email protected]
Article: e1072674 | Received 08 Jul 2015, Accepted 08 Jul 2015, Published online: 10 Jun 2016

Figures & data

Figure 1. Antitumor immune responses induced by ALA-PDT-treated immunogenic apoptotic cells. ALA-PDT-treated apoptotic cells work as sources of tumor antigens to stimulate the maturations of DCs. T cell immunity is initiated by the mature DCs, preventing tumor growth.

Figure 1. Antitumor immune responses induced by ALA-PDT-treated immunogenic apoptotic cells. ALA-PDT-treated apoptotic cells work as sources of tumor antigens to stimulate the maturations of DCs. T cell immunity is initiated by the mature DCs, preventing tumor growth.

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