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RIPK3—a predictive marker for personalized immunotherapy?

Article: e1075695 | Received 17 Jul 2015, Accepted 17 Jul 2015, Published online: 08 Apr 2016

Figures & data

Figure 1. RIPK3-positive (upper panels) but not RIPK3-negative cancer cells (lower panels) undergo necroptosis in response to PolyIC leading to release of the alarmin IL-1α and dendritic cell activation.

Figure 1. RIPK3-positive (upper panels) but not RIPK3-negative cancer cells (lower panels) undergo necroptosis in response to PolyIC leading to release of the alarmin IL-1α and dendritic cell activation.