Regulatory network controls microbial biofilm development, with Candida albicans as a representative: from adhesion to dispersal

Figures & data

Figure 1. Four steps of C. albicans biofilm development. In the adherence step, yeast-form cells adhere to the substrate. In the initiation step, cells form microcolonies and hyphae begin to form. In the maturation step, the biofilm biomass expands. In the dispersal step, yeast-form cells are released to surrounding environment.

Figure 2. Gene regulation during the formation of C. albicans biofilm. Different genes play a role in different steps during the formation of the envelope. Arrows represent positive relationships; T-shaped bars represent negative relationships.