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Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 47, 2019 - Issue 1
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Research Article

Associations between IL-23R gene polymorphisms and the susceptibility of rheumatoid arthritis: a meta-analysis

Qinghua Zoua Department of Rheumatology, West China Hospital, Sichuan University, Chengdu, China;b Department of Rheumatology and Immunology, The First Hospital Affiliated to Army Medical University, Chongqing, China
,
Yi Zhaoa Department of Rheumatology, West China Hospital, Sichuan University, Chengdu, China
,
Yong Wangb Department of Rheumatology and Immunology, The First Hospital Affiliated to Army Medical University, Chongqing, China
,
Yongfei Fangb Department of Rheumatology and Immunology, The First Hospital Affiliated to Army Medical University, Chongqing, ChinaCorrespondence[email protected] [email protected]
&
Yi Liua Department of Rheumatology, West China Hospital, Sichuan University, Chengdu, ChinaCorrespondence[email protected] [email protected]
Pages 951-956 | Received 27 Sep 2018, Accepted 22 Dec 2018, Published online: 11 Mar 2019

Figures & data

Figure 1. Flow diagram of article selection process.

Figure 1. Flow diagram of article selection process.

Table 1. Principal characteristics of the studies included in the meta-analysis.

Figure 2. Forest plot of RA susceptibility associated with IL-23R gene rs2201841 polymorphism under the G vs. A model. The squares and horizontal lines correspond to the study-specific OR and 95% CI. The area of the squares reflects the weight (inverse of the variance). The diamond represents the summary OR and 95% CI.

Figure 2. Forest plot of RA susceptibility associated with IL-23R gene rs2201841 polymorphism under the G vs. A model. The squares and horizontal lines correspond to the study-specific OR and 95% CI. The area of the squares reflects the weight (inverse of the variance). The diamond represents the summary OR and 95% CI.

Table 2. IL-23R Gene polymorphisms and RA susceptibility.

Figure 3. Sensitivity analysis for IL-23R gene rs2201841 polymorphism under the allele A vs. allele G model.

Figure 3. Sensitivity analysis for IL-23R gene rs2201841 polymorphism under the allele A vs. allele G model.

Figure 4. Begg’s funnel plot for publication bias. Each point represents a separate study for the indicated association. Log(OR): natural logarithm of OR; Horizontal line: mean effect size.

Figure 4. Begg’s funnel plot for publication bias. Each point represents a separate study for the indicated association. Log(OR): natural logarithm of OR; Horizontal line: mean effect size.

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