Figures & data
Figure 1. Schwann cells interfering with miR-148b. Compared with miR-con group, *P < .05; compared with anti-miR-con group, #P < .05.
![Figure 1. Schwann cells interfering with miR-148b. Compared with miR-con group, *P < .05; compared with anti-miR-con group, #P < .05.](/cms/asset/49b5718e-0eec-4012-8972-93737bbfc207/ianb_a_1609008_f0001_b.jpg)
Figure 2. Effects of miR-148b intervention on Schwann cell activity. Compared with miR-con group, *P < .05; compared with anti-miR-con group, #P < .05.
![Figure 2. Effects of miR-148b intervention on Schwann cell activity. Compared with miR-con group, *P < .05; compared with anti-miR-con group, #P < .05.](/cms/asset/3e567ce8-6bc6-4156-a514-b3de3daf4104/ianb_a_1609008_f0002_b.jpg)
Figure 3. Effects of miR-148b intervention on Schwann cell migration. Compared with miR-con group, *P < .05; compared with anti-miR-con group, #P < .05.
![Figure 3. Effects of miR-148b intervention on Schwann cell migration. Compared with miR-con group, *P < .05; compared with anti-miR-con group, #P < .05.](/cms/asset/1128ff87-ced2-438a-a2b5-36554dee4632/ianb_a_1609008_f0003_c.jpg)
Figure 4. MiR-148b targeting CALR. (A) miR-148b targeting combined with the sequence information of the CALR mRNA 3’UTR; (B) the effect of miR-148b on the activity of Schwann cells luciferase; (C) the effect of miR-148b on the expression of CALR protein in Schwann cells; Compared with the miR-con group, *P < .05; compared with the anti-miR-con group, #P < .05.
![Figure 4. MiR-148b targeting CALR. (A) miR-148b targeting combined with the sequence information of the CALR mRNA 3’UTR; (B) the effect of miR-148b on the activity of Schwann cells luciferase; (C) the effect of miR-148b on the expression of CALR protein in Schwann cells; Compared with the miR-con group, *P < .05; compared with the anti-miR-con group, #P < .05.](/cms/asset/e2b77651-3fe6-4103-a153-78293645b9fc/ianb_a_1609008_f0004_b.jpg)
Figure 5. Intervention of CALR affects proliferation and migration of Schwann cells. (A) Effect of intervention of CALR on the expression of CALR protein in Schwann cells; (B) Effect of intervention of CALR on Schwann cell activity; (C) Effect of intervention of CALR on migration in Schwann cells; Compared with si-con group, *P < .05; compared with the Ctrl group, #P < .05.
![Figure 5. Intervention of CALR affects proliferation and migration of Schwann cells. (A) Effect of intervention of CALR on the expression of CALR protein in Schwann cells; (B) Effect of intervention of CALR on Schwann cell activity; (C) Effect of intervention of CALR on migration in Schwann cells; Compared with si-con group, *P < .05; compared with the Ctrl group, #P < .05.](/cms/asset/ba68068d-08a9-451f-9a88-20e2f3036174/ianb_a_1609008_f0005_b.jpg)
Figure 6. Effects of intervention of miR-148b and CALR on proliferation and migration of Schwann cells. (A) Effect of intervention of miR-148b and CALR on the expression of Schwann cell CALR protein; (B) Effect of intervention of miR-148b and CALR on Schwann cell activity; (C) Effect of intervention of miR-148b and CALR on Schwann cell migration; Compared with the anti-miR-con group, *P < .05; compared with the anti-miR-con + si-con group, #P < .05.
![Figure 6. Effects of intervention of miR-148b and CALR on proliferation and migration of Schwann cells. (A) Effect of intervention of miR-148b and CALR on the expression of Schwann cell CALR protein; (B) Effect of intervention of miR-148b and CALR on Schwann cell activity; (C) Effect of intervention of miR-148b and CALR on Schwann cell migration; Compared with the anti-miR-con group, *P < .05; compared with the anti-miR-con + si-con group, #P < .05.](/cms/asset/65ac6e26-bd31-4d90-b0a2-ae3aa70788c4/ianb_a_1609008_f0006_b.jpg)