Long non-coding RNA NEAT1 can predict various malignant tumour lympha node metastasis: a meta-analysis

Figures & data

Figure 1. Flow diagram of the study search and selection process.

Table 1. Summary of the eight included studies.

						NEAT1 expression				NEAT1
Study detection	Year	Country	Cancer type	Total number	Tumour stage	High with LNM (+)	Low with LNM (+)	High with LNM (−)	Low with LNM (−)	Method
Li	2015	China	CC	239	I–IV	76	71	34	58	qRT-PCR
Chen	2015	China	EC	106	I–IV	32	18	20	26	qRT-PCR
Li	2018	China	LC	73	I–IV	29	17	8	19	qRT-PCR
Sun	2016	China	LC	96	I–IV	50	7	17	22	qRT-PCR
Zhao	2017	China	BC	70	I–III	17	9	17	27	qRT-PCR
Li	2016	China	EMC	75	I–IV	24	4	10	37	qRT-PCR
Huang	2016	China	PC	86	I–IV	35	18	27	6	qRT-PCR
Li	2017	China	RC	76	I–IV	18	6	19	33	qRT-PCR

CC: Colorectal cancer; EC: esophageal cancer; LC: lung cancer; BC: breast cancer; EMC: endometrial cancer; PC: pancreatic cancer; RC: renal cancer.

Figure 2. Forest plot of the association between NEAT1 expression and lymph node metastasis.

Figure 3. Funnel plot of the publication bias for lymph node metastasis.

Figure 4. Sensitivity analyses of studies concerning NEAT1.