2,455
Views
26
CrossRef citations to date
0
Altmetric
Research Article

Gold nano particles synthesized from Magnolia officinalis and anticancer activity in A549 lung cancer cells

, , , , &
Pages 3101-3109 | Received 17 May 2019, Accepted 10 Jun 2019, Published online: 25 Jul 2019

Figures & data

Figure 1. (A) UV-visible absorption spectrum of synthesized AuNPs. (B) Dynamic light scattering (DLS) images of AuNPs synthesized from Magnolia officinalis and the size of the nanoparticles is 128 nm.

Figure 1. (A) UV-visible absorption spectrum of synthesized AuNPs. (B) Dynamic light scattering (DLS) images of AuNPs synthesized from Magnolia officinalis and the size of the nanoparticles is 128 nm.

Figure 2. Atomic force microscopyanalysis of gold nanoparticles synthesized from Magnolia officinalis.

Figure 2. Atomic force microscopyanalysis of gold nanoparticles synthesized from Magnolia officinalis.

Figure 3. (A) High resolution transmission electron microscopy (HR-TEM) and (B) Energy dispersive X-ray (EDX) and analysis of AuNPs synthesized from Magnolia officinalis.

Figure 3. (A) High resolution transmission electron microscopy (HR-TEM) and (B) Energy dispersive X-ray (EDX) and analysis of AuNPs synthesized from Magnolia officinalis.

Figure 4. Fourier transforms infrared (FTIR) spectroscopy analysis of AuNPs synthesized from Magnolia officinalis.

Figure 4. Fourier transforms infrared (FTIR) spectroscopy analysis of AuNPs synthesized from Magnolia officinalis.

Figure 5. Cytotoxic potential of AuNPs from Magnolia officinalis in A549 cells. This experiment was repeated thrice and the bars in the graph represent S.E. (*p < .05)

Figure 5. Cytotoxic potential of AuNPs from Magnolia officinalis in A549 cells. This experiment was repeated thrice and the bars in the graph represent S.E. (*p < .05)

Figure 6. Effect of AuNPs from Magnolia officinalis arbitrated ROS measurements in A549 cells. This experiment was repeated thrice and the bars in the graph represent S.E. (*p < .05, #p < .01).

Figure 6. Effect of AuNPs from Magnolia officinalis arbitrated ROS measurements in A549 cells. This experiment was repeated thrice and the bars in the graph represent S.E. (*p < .05, #p < .01).

Figure 7. AuNPs mediated apoptotic morphological studied by TUNEL assay and DAPI/PI staining.

Figure 7. AuNPs mediated apoptotic morphological studied by TUNEL assay and DAPI/PI staining.

Figure 8. Western blotting images for Bax, Bcl-2, Bid, β-actin, Beclin-1, caspase-3 protein expression in AuNPs treated A549 cells.

Figure 8. Western blotting images for Bax, Bcl-2, Bid, β-actin, Beclin-1, caspase-3 protein expression in AuNPs treated A549 cells.