Erectile function and its impact on quality of life in Japanese men on hemodialysis

Figures & data

Table 1. Clinical and biological characteristics of patients

	Total (n = 65)	Relatively severe ED (n = 54)	Relatively mild ED (n = 11)	p-value
Age (years)	62.8 ± 11.8	65.1 ± 9.8	51.5 ± 14.6	<0.001
Marital status with a partner, n (%)	44 (68)	38 (86)	4 (36)	0.002
Duration of hemodialysis (months)	130 ± 110	132 ± 112	122 ± 104	0.77
Body mass index (kg/m^2)	21.9 ± 3.2	22.1 ± 3.3	21.4 ± 3.1	0.18
Systolic blood pressure (mmHg)	151 ± 24	152 ± 24	148 ± 22	0.63
Diastolic blood pressure (mmHg)	82 ± 15	81 ± 14	84 ± 17	0.65
Diabetes mellitus, n (%)	17 (26)	16 (30)	1 (9)	0.30
Cardiovascular disease, n (%)	13 (20)	12 (27)	1 (9)	0.38
Ankle-brachial index standard value (0.9–1.4), n (%)	19 (29)	15 (28)	4 (36)	0.02
Depression no (HADS-D ≤ 7 ), n (%)	36 (55)	27 (50)	9 (82)	0.11
Hemoglobin (g/dL)	11.1 ± 0.8	11.2 ± 0.9	11.0 ± 0.6	0.09
Albumin (g/dL)	3.6 ± 0.4	3.6 ± 0.3	3.8 ± 0.5	0.18
Free testosterone (pg/mL)	4.6 ± 2.4	4.3 ± 2.2	6.4 ± 2.8	0.04
Prolactin (ng/mL)	35.3 ± 51.9	38.6 ± 56.4	19.8 ± 9.5	0.03

Notes: ED, erectile dysfunction; HADS-D, the surveys of Hospital Anxiety and Depression Scale subscales for depression.

Table 2. Univariate and multivariate analyses of the association between several factors and the severity of ED in SHIM

	Univariate		Multivariate
	p-value	OR	p-value	OR
Age (<65 vs. ≧65)	0.01	8.3	0.03	6.9
Marital status (without vs. with a partner)	0.04	4.2	0.14	3.3
Duration of hemodialysis (<100 vs. ≧100)	0.70	1.3
Body mass index (<21.5 vs. ≧21.5)	0.87	1.1
Systolic blood pressure (<150 vs. ≧150)	0.58	1.5
Diastolic blood pressure (<80 vs. ≧80)	0.72	1.3
Ankle-brachial index (standard value vs. other value)	0.03	4.6	0.08	3.9
Diabetes mellitus (no vs. yes)	0.16	4.6
Cardiovascular disease (no vs. yes)	0.34	2.9
HADS-D (<8 vs. ≧8)	0.07	4.5
Hemoglobin (≧11.1 vs. <11.1)	0.27	0.5
Albumin (≧3.6 vs. <3.6)	0.45	1.8
Free testosterone (≧4.4 vs. <4.4)	0.05	5.1
Prolactin (<18 vs. ≧18)	0.42	2.4

Notes: ED, erectile dysfunction; HADS-D, the surveys of Hospital Anxiety and Depression Scale subscales for depression; SHIM, Sexual Health Inventory for Men.

Figure 1. Comparison of scale scores on the medical outcomes study 8-Item short form survey between relatively severe ED group and relatively mild ED group.

Notes: BP, bodily pain; ED, erectile dysfunction; GH, general health perception; MH, mental health; PF, physical function; RE, role limitation because of emotional problems; RP, role limitations because of physical health problem; SF, social function; VT, vitality; *p < 0.001