https://orcid.org/0000-0003-4667-4468
Figures & data
Figure 1. (Top) The areas that showed significant covariation of BOLD signals with cold discomfort in every subject, superimposed on the high-resolution MRI of the individual unrelated to the study. In all subjects, only the bilateral amygdala showed a negative correlation with the comfort score. (Bottom) Significant correlation of MR signal change by individual analysis. Normalized MR signal (relative to the global signal which was set to 100) in the right amygdala was plotted against the comfort score. The regression line was y = −2.46x + 144.8, X = 0.63, F(1,68) = 115.7 [P < 0.0001, F test). Adapted from [Citation13]
![Figure 1. (Top) The areas that showed significant covariation of BOLD signals with cold discomfort in every subject, superimposed on the high-resolution MRI of the individual unrelated to the study. In all subjects, only the bilateral amygdala showed a negative correlation with the comfort score. (Bottom) Significant correlation of MR signal change by individual analysis. Normalized MR signal (relative to the global signal which was set to 100) in the right amygdala was plotted against the comfort score. The regression line was y = −2.46x + 144.8, X = 0.63, F(1,68) = 115.7 [P < 0.0001, F test). Adapted from [Citation13]](/cms/asset/f440efc7-cfc7-4296-b490-e89543bda5f9/ktmp_a_1959288_f0001_b.gif)
Figure 2. Thermal comfort activations included the midcingulate cortex (MCC) (y = 16 and −4), inferior frontal gyrus (IFG) (y =16), superior frontal gyrus (SFG) (y = 16), supplementary motor area (SMA) (y = −4), premotor cortices (y = −4), primary somatosensory (Post CG) (y = −20 and −30), and motor cortices (Pre CG) (y =−20), thalamus (y = −20), bilateral superior temporal gyri (STG) (y = −20 and −30) and dentate nucleus of the cerebellum [y = −56). y – Distance from anterior commissure in mm. Positive values are anterior, and negative values are posterior to the anterior commissure. Adapted from “Brain activation associated with ratings of the hedonic component of thermal sensation during whole-body warming and cooling.” By [Citation64]
![Figure 2. Thermal comfort activations included the midcingulate cortex (MCC) (y = 16 and −4), inferior frontal gyrus (IFG) (y =16), superior frontal gyrus (SFG) (y = 16), supplementary motor area (SMA) (y = −4), premotor cortices (y = −4), primary somatosensory (Post CG) (y = −20 and −30), and motor cortices (Pre CG) (y =−20), thalamus (y = −20), bilateral superior temporal gyri (STG) (y = −20 and −30) and dentate nucleus of the cerebellum [y = −56). y – Distance from anterior commissure in mm. Positive values are anterior, and negative values are posterior to the anterior commissure. Adapted from “Brain activation associated with ratings of the hedonic component of thermal sensation during whole-body warming and cooling.” By [Citation64]](/cms/asset/bcb76f8b-0c69-4b0e-8645-2389a9b7f2ce/ktmp_a_1959288_f0002_oc.jpg)