http://orcid.org/0000-0001-7873-1389View further author informationFigure 1. Role of MAD2L1h/Mad2pSc in the S and M phases of the cell cycle. (A) During mitosis, MAD2L1h/Mad2pSc acts as a component of the spindle assembly checkpoint. (B) During S-phase, Mad2p promotes S-phase cyclin mRNA translation by modulating the association of the translational inhibitor Caf20p with the replication machinery. Abbreviations: APC: Anaphase promoting complex; h: human; Sc: Saccharomyces cerevisiae; eIF: eukaryotic initiation factor.
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