Molecular & Cellular Oncology, Volume 5, Issue 4 (2018)

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Molecular & Cellular Oncology, Volume 5, Issue 4 (2018)

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Author's Views

Opinion
The decisive role of fumarase: Responsive signaling to glucose deficiency
Qiujing Yu, Ting Wang & Yuhui Jiang
Article: e1363848
Published online: 16 May 2018
AbstractforThe decisive role of fumarase: Responsive signaling to glucose deficiency | Full Text | References | PDF (415.6 KB)
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Review

Review
Another one bites the dust; ARTS enables degradation of Bcl-2 by XIAP
Dana Mamriev & Sarit Larisch
Article: e1441630
Published online: 25 Jun 2018
AbstractforAnother one bites the dust; ARTS enables degradation of Bcl-2 by XIAP | Full Text | References | PDF (408.1 KB)
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Author's Views

Opinion
Complex role of SIRT6 in NF-κB pathway regulation
Irene Santos-Barriopedro & Alejandro Vaquero
Article: e1445942
Published online: 24 May 2018
AbstractforComplex role of SIRT6 in NF-κB pathway regulation | Full Text | References | PDF (366.8 KB)
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Opinion
A Case of mistaken identity: Rhabdomyosarcoma development from endothelial progenitor cells
Catherine J. Drummond & Mark E. Hatley
Article: e1448246
Published online: 16 May 2018
AbstractforA Case of mistaken identity: Rhabdomyosarcoma development from endothelial progenitor cells | Full Text | References | PDF (525.3 KB)
  • 1062 Views
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Opinion
FAK family kinases: The Yin and Yang of cancer cell invasiveness
Alessandro Genna & Hava Gil-Henn
Article: e1449584
Published online: 25 May 2018
AbstractforFAK family kinases: The Yin and Yang of cancer cell invasiveness | Full Text | References | PDF (464.9 KB)
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Opinion
Ewing sarcoma fusion oncogene: At the crossroads of transcription and DNA damage response
Aparna Gorthi & Alexander J. R. Bishop
Article: e1465014
Published online: 29 May 2018
First Page PreviewforEwing sarcoma fusion oncogene: At the crossroads of transcription and DNA damage response | Full Text | References | PDF (588.4 KB)
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Opinion
RIPK1-dependent mitophagy: A novel mechanism to eliminate cells detached from the extracellular matrix
Mark A. Hawk & Zachary T. Schafer
Article: e1465015
Published online: 10 May 2018
AbstractforRIPK1-dependent mitophagy: A novel mechanism to eliminate cells detached from the extracellular matrix | Full Text | References | PDF (447.1 KB)
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Opinion
Killing two birds with one stone: Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and radiosensitize tumors
Catherine Vander Linden & Cyril Corbet
Article: e1465016
Published online: 22 May 2018
AbstractforKilling two birds with one stone: Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and radiosensitize tumors | Full Text | References | PDF (540.8 KB)
  • 2247 Views
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Opinion
One gene to rule them all…and in the darkness bind them
Konstantinos V. Floros & Anthony C. Faber
Article: e1465881
Published online: 11 Jul 2018
AbstractforOne gene to rule them all…and in the darkness bind them | Full Text | References | PDF (605.8 KB)
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Opinion
DDR1 inhibition as a new therapeutic strategy for colorectal cancer
Audrey Sirvent, Marie Lafitte & Serge Roche
Article: e1465882
Published online: 23 Jul 2018
AbstractforDDR1 inhibition as a new therapeutic strategy for colorectal cancer | Full Text | References | PDF (662.8 KB)
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Opinion
Revisiting glucose metabolism in cancer: lessons from a PKM knock-in model
Taku Sato, Mami Morita, Miyuki Nomura & Nobuhiro Tanuma
Article: e1472054
Published online: 01 Aug 2018
AbstractforRevisiting glucose metabolism in cancer: lessons from a PKM knock-in model | Full Text | References | PDF (361.1 KB)
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Research Paper

Article
Examination of Hypoxanthine Guanine Phosphoribosyltransferase as a biomarker for colorectal cancer patients
Michelle H. Townsend, Abigail M. Felsted, Weston Burrup, Richard A. Robison & Kim L. O’Neill
Article: e1481810
Published online: 01 Aug 2018
AbstractforExamination of Hypoxanthine Guanine Phosphoribosyltransferase as a biomarker for colorectal cancer patients | Full Text | References | PDF (2.8 MB)
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Author's Views

Opinion
LSD1 inhibitors disrupt the GFI1 transcription repressor complex
Alba Maiques-Diaz, James T. Lynch, Gary J. Spencer & Tim C.P. Somervaille
Article: e1481813
Published online: 01 Aug 2018
AbstractforLSD1 inhibitors disrupt the GFI1 transcription repressor complex | Full Text | References | PDF (545.3 KB)
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Opinion
Exiting the dark side: A vital role for Caspase-3 in Yap signaling
Yahav Yosefzon & Yaron Fuchs
Article: e1494947
Published online: 06 Aug 2018
AbstractforExiting the dark side: A vital role for Caspase-3 in Yap signaling | Full Text | References | PDF (421.2 KB)
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Opinion
GRASP55 facilitates autophagosome maturation under glucose deprivation
Xiaoyan Zhang & Yanzhuang Wang
Article: e1494948
Published online: 06 Aug 2018
AbstractforGRASP55 facilitates autophagosome maturation under glucose deprivation | Full Text | References | PDF (610.9 KB)
  • 799 Views
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Opinion
A novel function for the mitotic checkpoint protein Mad2p in translation
Sophie Gay
Article: e1494949
Published online: 06 Aug 2018
AbstractforA novel function for the mitotic checkpoint protein Mad2p in translation | Full Text | References | PDF (430.9 KB)
  • 561 Views
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Opinion
Itraconazole perturbs colorectal cancer dormancy through SUFU-mediated WNT inhibition
Semiramis A. Popova & Simon J. A. Buczacki
Article: e1494950
Published online: 07 Aug 2018
AbstractforItraconazole perturbs colorectal cancer dormancy through SUFU-mediated WNT inhibition | Full Text | References | PDF (600.2 KB)
  • 1418 Views
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Opinion
T-cell leukemogenesis is an inappropriate lineage decision-making process: implications for precision oncology
Guillermo Rodríguez-Hernández, Sanil Bhatia, Carolina Vicente-Dueñas, Arndt Borkhardt, Julia Hauer & Isidro Sánchez-García
Article: e1497860
Published online: 07 Aug 2018
AbstractforT-cell leukemogenesis is an inappropriate lineage decision-making process: implications for precision oncology | Full Text | References | PDF (577.9 KB)
  • 605 Views
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Opinion
SETD2 in MLL-rearranged leukemia – a complex case
Anna Skucha, Jessica Ebner & Florian Grebien
Article: e1503492
Published online: 13 Aug 2018
AbstractforSETD2 in MLL-rearranged leukemia – a complex case | Full Text | References | PDF (252.3 KB)
  • 906 Views
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Opinion
EnABLing Cathepsin-Driven Melanoma Metastasis
Rakshamani Tripathi & Rina Plattner
Article: e1458016
Published online: 17 Aug 2018
AbstractforEnABLing Cathepsin-Driven Melanoma Metastasis | Full Text | References | PDF (586 KB)
  • 646 Views
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Opinion
PTPN2 as a promoter of colon carcinoma via reduction of inflammasome activation
Marianne R. Spalinger & Michael Scharl
Article: e1465013
Published online: 06 Jun 2018
AbstractforPTPN2 as a promoter of colon carcinoma via reduction of inflammasome activation | Full Text | References | PDF (458.5 KB)
  • 1506 Views
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Opinion
PSPC1 potentiates TGF-β-dependent metastatic dissemination
Hsi-Wen Yeh & Yuh-Shan Jou
Article: e1472058
Published online: 01 Aug 2018
AbstractforPSPC1 potentiates TGF-β-dependent metastatic dissemination | Full Text | References | PDF (624.3 KB)
  • 1148 Views
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Opinion
What a dog transmissible tumor can teach us about cancer regression
Ariberto Fassati
Article: e1472059
Published online: 06 Aug 2018
AbstractforWhat a dog transmissible tumor can teach us about cancer regression | Full Text | References | PDF (487.7 KB)
  • 1075 Views
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Opinion
Starving PTEN-deficient prostate cancer cells thrive under nutrient stress by scavenging corpses for their supper
Vaishali Jayashankar, Brendan T. Finicle & Aimee L. Edinger
Article: e1472060
Published online: 17 Aug 2018
AbstractforStarving PTEN-deficient prostate cancer cells thrive under nutrient stress by scavenging corpses for their supper | Full Text | References | PDF (469.5 KB)
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Opinion
ZMYND8 is a primary HIF coactivator that mediates breast cancer progression
Yan Chen, Yingfei Wang & Weibo Luo
Article: e1479619
Published online: 01 Aug 2018
AbstractforZMYND8 is a primary HIF coactivator that mediates breast cancer progression | Full Text | References | PDF (710.8 KB)
  • 1417 Views
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Opinion
CDC25 as a common therapeutic target for triple-negative breast cancer - the challenges ahead
Eldad Zacksenhaus, Jeff C. Liu, Letizia Granieri, Ioulia Vorobieva, Dong-Yu Wang, Ronak Ghanbari-Azarnier, Huiqin Li, Amjad Ali, Philip E.D. Chung, YoungJun Ju, Zhe Jiang & Mariusz Shrestha
Article: e1481814
Published online: 15 Aug 2018
AbstractforCDC25 as a common therapeutic target for triple-negative breast cancer - the challenges ahead | Full Text | References | PDF (447.9 KB)
  • 1078 Views
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Commentary

Article Commentary
Mediating the death of dormant tumor cells
Yuying Liu, Jiadi Lv & Bo Huang
Article: e1458013
Published online: 06 Aug 2018
AbstractforMediating the death of dormant tumor cells | Full Text | References | PDF (493.9 KB)
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Article Commentary
Does the BCL-2 family member BIK control lung carcinogenesis?
Yohannes A. Mebratu & Yohannes Tesfaigzi
Article: e1435182
Published online: 16 May 2018
AbstractforDoes the BCL-2 family member BIK control lung carcinogenesis? | Full Text | References | PDF (293.1 KB)
  • 565 Views
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Article Commentary
Calorie restriction for human aging: is there a potential benefit for cancer?
Anne Gilmore & Leanne Redman
Article: e1481811
Published online: 17 Aug 2018
AbstractforCalorie restriction for human aging: is there a potential benefit for cancer? | Full Text | References | PDF (236.3 KB)
  • 708 Views
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