Adverse reactions in patients treated with the one-bag method of N-acetylcysteine for acetaminophen ingestion

Figures & data

Figure 1. Flow chart of patients screened for adverse reactions to IV acetylcysteine (NAC) and treatments given.

Table 1. Frequencies of adverse reactions (n = 202).

	No. (%) patients	95% confidence interval
Any adverse reactions	33 (16.3%)	(11.5–22.2%)
Nausea	28 (13.9%)	(9.4–19.4%)
Any NAAR	8 (4.0%)	(1.7–7.7%)
Rash	5 (2.5%)	(0.8–5.7%)
Pruritus/itching	4 (2.0%)	(0.5–5.0%)
Shortness of breath	1 (0.5%)	(0.0–2.7%)

NAAR = non-allergic anaphylactoid reaction (rash, pruritus, itching, or shortness of breath) Confidence intervals calculated with https://www.sample-size.net/confidence-interval-proportion/ (Clinical & Translational Science Institute, University of California-San Francisco).