UNINEPHRECTOMY INCREASES KIDNEY β2-MICROGLOBULIN: CAN IT PLAY A ROLE IN THE PROGRESSION OF KIDNEY DAMAGE?

Figures & data

Figure 1. Total body scan (left) and time-course curve of kidney radioactivity (right) recorded in a normal rat after i.v. injection of ¹³¹I-β2-microglobulin.

Figure 2. Plasma radioactivity of ¹³¹I-β2-microglobulin (radioactivity per gram of plasma, percent of the injected dose) in uninephrectomized rats (•) and in controls (○) 2, 4 and 6 weeks after nephrectomy. On the left the values at the 12^th min after i.v. injection of ¹³¹I-β2-microglobulin (peak-time); on the right those at the 22^nd min. Mean values ± SD, *p < 0.05, **p < 0.001.

Figure 3. Kidney uptake of ¹³¹I-β2-microglobulin (radioactivity of total left kidney, percent of the injected dose) in uninephrectomized rats (•) and in controls (○) 2, 4 and 6 weeks after nephrectomy. On the left the values at the 12^th min after i.v. injection of ¹³¹I-β2-microglobulin (peak-time); on the right those at the 22^nd min. Mean values ± SD, **p < 0.001.

Figure 4. Kidney uptake of ¹³¹I-β2-microglobulin (radioactivity per gram of left kidney, percent of the injected dose) in uninephrectomized rats (•) and in controls (○) 2, 4 and 6 weeks after nephrectomy. On the left the values at the 12^th min after i.v. injection of ¹³¹I-β2-microglobulin (peak-time); on the right those at the 22^nd min. Mean values ± SD, *p < 0.05