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Expert Opinion on Emerging Drugs Volume 11, 2006 - Issue 1
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Review

Emerging drugs for the treatment of sepsis

Jérome Aboab Attending physician, University of Versailles Saint Quentin, Hospital Raymond Poincaré, Intensive Care Unit, 104 bd Raymond Poincaré, 92380 Garches, France;
,
Olivier Nardi Attending physician, University of Versailles Saint Quentin, Hospital Raymond Poincaré, Intensive Care Unit, 104 bd Raymond Poincaré, 92380 Garches, France;
,
Diane Lipiner Attending physician, University of Versailles Saint Quentin, Hospital Raymond Poincaré, Intensive Care Unit, 104 bd Raymond Poincaré, 92380 Garches, France;
,
Tarek Sharshar Attending physician, University of Versailles Saint Quentin, Hospital Raymond Poincaré, Intensive Care Unit, 104 bd Raymond Poincaré, 92380 Garches, France;
&
Djillali Annane Professor of Medicine, Head of the Intensive Care Unit, University of Versailles Saint Quentin, Hospital Raymond Poincaré, Intensive Care Unit, 104 bd Raymond Poincaré, 92380 Garches, France. [email protected]
Pages 7-22 | Published online: 27 Feb 2006
 
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Abstract

Septic shock still places a major burden on the healthcare system, although recent years have been marked by the demonstration that corticosteroids and activated protein C may substantially improve survival in selected populations. This review discusses the current management of septic shock and the potential development of new therapeutics following impressive advances in the pathomechanisms of septic shock.

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