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ORIGINAL RESEARCH

Anticancer Effects of Wild Baicalin on Hepatocellular Carcinoma: Downregulation of AKR1B10 and PI3K/AKT Signaling Pathways

, , , , , & show all
Pages 477-489 | Received 05 Jan 2024, Accepted 09 May 2024, Published online: 23 May 2024

Figures & data

Figure 1 The effect of SCU on the proliferation ability of HepG2 cells.

Notes: ***p < 0.001, ****p < 0.0001.
Figure 1 The effect of SCU on the proliferation ability of HepG2 cells.

Figure 2 The effect of SCU on the apoptosis ability of HepG2 cells.

Note: *p < 0.05.
Figure 2 The effect of SCU on the apoptosis ability of HepG2 cells.

Figure 3 The effect of SCU on the growth cycle of HepG2 cells. *, **, ****Represents p < 0.05, p < 0.01, p < 0.0001, respectively.

Figure 3 The effect of SCU on the growth cycle of HepG2 cells. *, **, ****Represents p < 0.05, p < 0.01, p < 0.0001, respectively.

Figure 4 The effect of SCU on the migration ability of HepG2 cells.

Note: *p < 0.05.
Figure 4 The effect of SCU on the migration ability of HepG2 cells.

Figure 5 The effect of SCU on the invasion ability of HepG2 cells. ****Represents p < 0.0001, respectively.

Figure 5 The effect of SCU on the invasion ability of HepG2 cells. ****Represents p < 0.0001, respectively.

Figure 6 The effect of SCU on the proliferation ability of HepG2 cells. ****Represents p < 0.0001, respectively.

Figure 6 The effect of SCU on the proliferation ability of HepG2 cells. ****Represents p < 0.0001, respectively.

Figure 7 Cluster diagram and volcano diagram.

Figure 7 Cluster diagram and volcano diagram.

Figure 8 Gene Ontology functional classification of differentially expressed genes in HepG2 cells treated with wild Baicalin.

Figure 8 Gene Ontology functional classification of differentially expressed genes in HepG2 cells treated with wild Baicalin.

Figure 9 SCU regulates the expression of PI3K and AKR1B10 proteins in HepG2 cells. ***, ****Represents p < 0.001, p < 0.0001, respectively.

Figure 9 SCU regulates the expression of PI3K and AKR1B10 proteins in HepG2 cells. ***, ****Represents p < 0.001, p < 0.0001, respectively.

Data Sharing Statement

Data will be available on request.