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Original Research

Satisfaction, preference and error occurrence of three dry powder inhalers as assessed by a cohort naïve to inhaler operation

, , , &
Pages 1949-1963 | Published online: 15 Jun 2018

Figures & data

Figure 1 A schematic diagram showing randomization and sequence of learning to use the different DPI devices.

Abbreviation: DPI, dry powder inhaler.
Figure 1 A schematic diagram showing randomization and sequence of learning to use the different DPI devices.

Figure 2 Satisfaction scores on different attributes of the three DPIs using a seven-point Likert-type scale.

Notes: Mean values are plotted and the error bars represent the SEM. *p≤0.05; **p≤0.01; ****p≤0.0001.
Abbreviations: DPIs, dry powder inhalers; SEM, standard error of the mean.
Figure 2 Satisfaction scores on different attributes of the three DPIs using a seven-point Likert-type scale.

Table 1 Differences of satisfactory scores between each DPI for each attribute

Figure 3 Overall satisfaction scores on a 0–100 scale to indicate the willingness of subjects to use each DPI (*p≤0.05; **p≤0.01).

Abbreviation: DPI, dry powder inhaler.
Figure 3 Overall satisfaction scores on a 0–100 scale to indicate the willingness of subjects to use each DPI (*p≤0.05; **p≤0.01).

Table 2 Preference of subjects for different attributes of the three DPIs

Figure 4 (A) Number of subjects who committed one or more critical errors during the two learning stages. (B) McNemar’s tests for the number of subjects who committed one or more critical errors during the two learning stages.

Note: *p≤0.05.
Abbreviation: DPIs, dry powder inhalers.
Figure 4 (A) Number of subjects who committed one or more critical errors during the two learning stages. (B) McNemar’s tests for the number of subjects who committed one or more critical errors during the two learning stages.

Table 3 Number and percentage of subjects who committed non-critical errors

Figure S1 Satisfaction scores on different attributes of the three DPIs as evaluated by male and female subjects.

Notes: Mean values are plotted and the error bars represent the SEM. *p≤0.05; **p≤0.01.

Abbreviations: DPIs, dry powder inhalers; SEM, standard error of the mean.

Figure S1 Satisfaction scores on different attributes of the three DPIs as evaluated by male and female subjects.Notes: Mean values are plotted and the error bars represent the SEM. *p≤0.05; **p≤0.01.Abbreviations: DPIs, dry powder inhalers; SEM, standard error of the mean.

Figure S2 Satisfaction scores on different attributes of the three DPIs as evaluated by subjects below 60 years of age or above or equal to 60 years of age.

Notes: Mean values are plotted and the error bars represent the SEM. *p≤0.05; **p≤0.01; ***p≤0.001.

Abbreviations: DPIs, dry powder inhalers; SEM, standard error of the mean.

Figure S2 Satisfaction scores on different attributes of the three DPIs as evaluated by subjects below 60 years of age or above or equal to 60 years of age.Notes: Mean values are plotted and the error bars represent the SEM. *p≤0.05; **p≤0.01; ***p≤0.001.Abbreviations: DPIs, dry powder inhalers; SEM, standard error of the mean.

Figure S3 Satisfaction scores on different attributes of the three DPIs by male and female subjects.

Notes: Mean values are plotted and the error bars represent the SEM. No significance was detected.

Abbreviations: DPIs, dry powder inhalers; SEM, standard error of the mean.

Figure S3 Satisfaction scores on different attributes of the three DPIs by male and female subjects.Notes: Mean values are plotted and the error bars represent the SEM. No significance was detected.Abbreviations: DPIs, dry powder inhalers; SEM, standard error of the mean.

Figure S4 Satisfaction scores on different attributes of the three DPIs by subjects <60 and ≥60 years of age.

Notes: Mean values are plotted and the error bars represent the SEM. *p≤0.05.

Abbreviations: DPIs, dry powder inhalers; SEM, standard error of the mean.

Figure S4 Satisfaction scores on different attributes of the three DPIs by subjects <60 and ≥60 years of age.Notes: Mean values are plotted and the error bars represent the SEM. *p≤0.05.Abbreviations: DPIs, dry powder inhalers; SEM, standard error of the mean.

Table S1 List of critical and non-critical errors for each dry powder inhaler

Table S2 0.2 SD and 0.5 SD of satisfactory scores of the three DPIs

Table S3 Total number of non-critical errors committed during use of the three DPIs