The relationship between exercise capacity and different functional markers in pulmonary rehabilitation for COPD

Figures & data

Table 1 Patients’ demographic, lung function, comorbidity, and smoking habit characteristics

Characteristics, N=327
Age (years)	64±8
Male/female	181/146
BMI (kg/m^2)	27±7
FEV1 (% predicted)	45±19
Hypertension	257 (79%)
Diabetes	85 (26%)
Pulmonary hypertension	104 (32%)
Quitting of smoking	245 (75%)

Note: Data presented as mean ± SD, n/n, and n (%).

Abbreviations: BMI, body mass index; FEV₁, forced expiratory volume in the first second.

Table 2 Correlation between 6MWD and other functional markers

Demographic and functional parameters	6MWD
BODE-index	−0.6
Alternative Scale	−0.56
mMRC	−0.54
CAT	−0.4
IVC (L)	0.34
IVC%	0.27
Breath holding time	0.24
FEV1	0.22
FVC	0.22
Grip strength	0.2
Chest wall expansion	0.2
Age	−0.18
FEV1/FVC	0.16
BMI	0.12

Abbreviations: 6MWD, 6-minute walking distance; BMI, body mass index; BODE-index, Body mass index, airflow Obstruction, Dyspnea and Exercise capacity; CAT, COPD Assessment Test; FEV₁, forced expiratory volume in the first second; FVC, forced vital capacity; IVC, inspiratory vital capacity; mMRC, modified Medical Research Dyspnea Scale.

Figure 1 Scatterplot of 6-minutes walking test (6MWD in m) between values at the start of rehabilitation and the change as an effect of rehabilitation.

Abbreviation: 6MWD, 6-minute walking distance.

Table 3 Correlation between IVC (L) and other functional markers

Demographic and functional parameters	IVC (L)
Gender	−0.6
Grip strength	0.6
IVC%	0.57
FVC	0.51
Chest wall expansion	0.48
BODE-index	−0.39
Stage of COPD	−0.36
FEV1	0.35
Breath holding time	0.35
6MWD	0.34
Alternative Scale	−0.34
mMRC	−0.26
CAT	−0.16
BMI	0.05

Abbreviations: 6MWD, 6-minute walking distance; BMI, body mass index; BODE-index, Body mass index, airflow Obstruction, Dyspnea and Exercise capacity; CAT, COPD Assessment Test; FEV₁, forced expiratory volume in the first second; FVC, forced vital capacity; IVC, inspiratory vital capacity; mMRC, modified Medical Research Dyspnea Scale.

Figure 2 Scatterplot of inspiratory vital capacity (IVC) between the values at the start of rehabilitation and the change as an effect of rehabilitation.