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Original Research

Excess risk of major vascular diseases associated with airflow obstruction: a 9-year prospective study of 0.5 million Chinese adults

, , , , , , , , , , , , , , & show all
Pages 855-865 | Published online: 08 Mar 2018

Figures & data

Table 1 Baseline characteristics of participants by baseline AFO status (defined by spirometry criteria only)

Table 2 Events, adjusted event rates, and HRs for selected disease outcomes by prevalent AFOTable Footnote*

Figure 1 Adjusted HRs for vascular mortality by baseline AFO status.

Notes: Stratified by sex, age, study area, education, smoking status, alcohol consumption, physical activity, BMI, and self-assessed health status. HRs and 95% CIs are floated measures. Solid squares represent the HR, with area inversely proportional to the variance of the log HR. Horizontal lines represent the corresponding 95% CIs, which are floated measures. The dotted line represents the overall HR.
Abbreviations: AFO, airflow obstruction; BMI, body mass index; MET, metabolic equivalent of task; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity.
Figure 1 Adjusted HRs for vascular mortality by baseline AFO status.

Figure 2 Adjusted HRs for respiratory diseases by severity of AFO.

Notes: (A) Pneumonia: ICD 10 codes J12–J18. (B) Lung cancer: ICD 10 codes C33–C34. (C) Other respiratory diseases: ICD 10 codes J00–J99 excluding J12–J18 and J41–J44. Black boxes represent RRs, with area inversely proportional to variance of log RR, and vertical lines represent corresponding 95% CIs. Values above the vertical lines are HRs, and values below them are the number of events in respective categories.
Abbreviations: AFO, airflow obstruction; ICD 10, International Classification of Diseases Version 10.
Figure 2 Adjusted HRs for respiratory diseases by severity of AFO.

Table 3 Event, adjusted event rates, and HRs for selected disease outcomes by different grades of prevalent AFOTable Footnote*

Figure 3 Adjusted HRs for major cardiovascular diseases by severity of AFO.

Notes: (A) Major coronary event, for non-fatal: ICD 10 codes MI I21–I23; or for fatal: IHD ICD 10 codes I20–I25. (B) Hemorrhagic stroke, ICD 10 code I61. (C) Heart failure: ICD 10 codes I50. (D) All cardiovascular deaths: ICD 10 codes I00–I99. Black boxes represent RRs, with area inversely proportional to variance of log RR, and vertical lines represent corresponding 95% CIs. Values above the vertical lines are HRs, and values below them are the number of events in respective categories.
Abbreviations: AFO, airflow obstruction; ICD 10, International Classification of Diseases Version 10.
Figure 3 Adjusted HRs for major cardiovascular diseases by severity of AFO.

Table 4 Members of the China Kadoorie Biobank collaborative group