COPD as a risk factor of the complications in lower limb arthroplasty: a patient-matched study

Figures & data

Figure 1 Flowchart of the patients included in the study and patient matching.

Abbreviations: ASA, American Society of Anaesthesiologists; BMI, body mass index; THA, total hip arthroplasty; TKA, total knee arthroplasty.

Table 1 Preoperative characteristics and risk factors for study patients

Variables	All study patients			Matched groups
	Non-COPD group (n=2,536)	COPD group n=224)	p-value	Non-COPD group (n=224)	COPD group (n=224)	p-value
Age (years)	69.5±9.8	70.6±9.2	0.116	71.0±9.25	70.6±9.2	0.647
Male, n (%)	1,026 (40.4)	82 (36.6)	0.600	82 (36.6)	82 (36.6)	0.883
BMI (kg/m^2)	28.6±5.2	30.5±6.5	<0.001	30.2±6.2	30.5±6.5	0.634
THA, n (%)	1,419 (51.4)	106 (47.3)	0.262	104 (46.4)	106 (47.3)	0.962
Regional anesthesia, n (%)	1,614 (63.6)	141 (62.9)	0.900	149 (66.5)	141 (62.9)	0.574
Arterial hypertension, n (%)a	1,936 (70.1)	185 (82.5)	0.537	190 (84.8)	185 (82.5)	0.824
Anticoagulation, n (%)a	630 (22.8)	67 (29.9)	0.018	66 (29.4)	67 (29.9)	0.970
CHD, n (%)a	533 (19.3)	81 (36.1)	0.027	76 (33.9)	81 (36.1)	0.722
Diabetes mellitus, n (%)a	422 (15.2)	49 (21.8)	0.951	58 (25.9)	49 (21.8)	0.299
CRD, n (%)a	498 (18)	57 (25.4)	0.814	52 (23.2)	57 (25.4)	0.536
ASA 3, n (%)a	771 (27.9)	136 (60)	<0.001	133 (59.3)	136 (60)	0.420

Note:

a Risk factors.

Abbreviations: BMI, body mass index; THA, total hip arthroplasty; CHD, chronic heart disease; CRD, chronic renal disease; ASA 3, American Society of Anaesthesiologists’ score 3.

Table 2 Differences in postoperative complications and parameters

Variables	Non-COPD group (n=224)	COPD group (n=224)	p-value
CRP, preoperative (mg/L)	4.41±3.79	6.55±6.88	<0.001
Leukocytes, preoperative × 10^9/L	7.19±2.191	7.76±2.46	0.010
Intensive care admission, n (%)	94 (41.9)	119 (53.1)	0.023
Pneumonia, n (%)	0 (0)	5 (2.2)	0.024
Length of stay, days, n (%)	13.76 (6.4)	14.13 (6.5)	0.556
Length of stay in ICU, days, n (%)	1.02 (0.2)	1.03 (0.2)	0.075
General complication rate, n (%)	36 (16.0)	47 (20.1)	0.255
Wound infection rate, n (%)	4 (0.17)	7 (0.3)	0.353
Transfusion rate, n (%)	20 (8.9)	30 (13.4)	0.126

Abbreviations: CRP, C-reactive protein; ICU, intense care unit.