A novel CT-emphysema index/FEV₁ approach of phenotyping COPD to predict mortality

Li-Cher Loh1 Department of Medicine, RCSI & UCD Malaysia Campus, Penang, MalaysiaCorrespondence[email protected]

Choo-Khoon Ong1 Department of Medicine, RCSI & UCD Malaysia Campus, Penang, Malaysia

Hyun-Jung Koo2 Department of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, [email protected]

Sang Min Lee2 Department of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, [email protected]

Jae-Seung Lee3 Department of Pulmonary and Critical Care Medicine, and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

Yeon-Mok Oh3 Department of Pulmonary and Critical Care Medicine, and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

Joon-Beom Seo2 Department of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, [email protected]

Sang-Do Lee3 Department of Pulmonary and Critical Care Medicine, and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Figures & data

Table 1 Baseline patient characteristics (n=112)

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Figure 1 Scatter plot showing relationships between CT-emphysema index/FEV₁ COPD phenotypes and GOLD groups among patients (n=112).

Note: Right upper quadrant = emphysema-dominant; right lower quadrant = mild mixed airway-emphysema disease; left lower quadrant = airway-dominant; left upper quadrant = severe mixed airway-emphysema.
Abbreviations: BD, bronchodilator; CT, computed tomography; FEV₁, forced expiratory volume in 1 second; GOLD, Global Initiative for Chronic Obstructive Lung Disease.

Figure 1 Scatter plot showing relationships between CT-emphysema index/FEV1 COPD phenotypes and GOLD groups among patients (n=112).

Figure 2 Kaplan–Meier survival probability estimates according to CT-emphysema index/FEV₁ COPD phenotypes.

Abbreviations: CT, computed tomography; FEV₁, forced expiratory volume in 1 second.

Figure 2 Kaplan–Meier survival probability estimates according to CT-emphysema index/FEV1 COPD phenotypes.Abbreviations: CT, computed tomography; FEV1, forced expiratory volume in 1 second.

Figure 3 Kaplan–Meier survival probability estimates according to GOLD 2017 groups. Abbreviation: GOLD, Global Initiative for Chronic Obstructive Lung Disease.

Table 2 Predictors in Cox proportional hazard models of COPD-associated mortality

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A novel CT-emphysema index/FEV₁ approach of phenotyping COPD to predict mortality

Table 1 Baseline patient characteristics (n=112)

Table 2 Predictors in Cox proportional hazard models of COPD-associated mortality

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A novel CT-emphysema index/FEV1 approach of phenotyping COPD to predict mortality

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Table 1 Baseline patient characteristics (n=112)

Table 2 Predictors in Cox proportional hazard models of COPD-associated mortality

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A novel CT-emphysema index/FEV₁ approach of phenotyping COPD to predict mortality