The impact of pulmonary rehabilitation on severe physical inactivity in patients with chronic obstructive pulmonary disease: a pilot study

Figures & data

Table 1 Group characteristics (n=57)

	Visit 1
Age (years), median (range)	68 (50–80)
Female gender, n (%)	30 (53)
BMI, median (range)	27 (17–51)
FEV1 (% predicted), median (range)	50 (22–96)
GOLD, n (%)
A	0 (0)
B	28 (49)
C	0 (0)
D	29 (51)
Community/hospital, n (%)	43 (75)/14 (25)
CAT, median (range)	17 (4–32)
mMRC, median (range)	2 (1–4)
AECOPD in the recent year, median (range)	1 (0–7)

Abbreviations: AECOPD, acute exacerbation in COPD; BMI, body mass index; CAT, COPD Assessment Test.

Table 2 Impact of pulmonary rehabilitation on time spent in physical activity and number of patients being active for ≥150 minutes/ week measured using activity monitor (SenseWear^©) during 1 week

	All participants (n=57)		SPI at baseline (n=31)
	Baseline	Follow-up	Baseline	Follow-up
Hours/week at ≥3.0 MET (moderate physical activity), median (range)	6.0 (0–59)	7.7 (0.1–32)	4.4 (0.2–21)	4.8 (0.1–14)
Patients with ≥3.0 MET (moderate physical activity) in ≥150 minutes/week, n (%)	39 (74)	42 (79)	21 (69)	22 (76)
Hours/week at ≥2.0 MET (light physical activity), median (range)	18.8 (0.8–61)	21.5 (1.9–59)a	9.9 (0.8–39)	16.8 (1.9–31)
Patients with ≥2.0 MET (light physical activity) in ≥150 minutes/week, n (%)	50 (94)	52 (98)	31 (97)	28 (97)

Note:

a P<0.05, intragroup difference between time points.

Abbreviations: MET, Metabolic Equivalent of Task; SPI, severe physical inactivity.

Figure 1 Flowchart of patients included in the study.

Abbreviation: AECOPD, acute exacerbation in COPD; SPI, severe physical inactivity.

Table 3 Subgroup analyses of patients with SPI at baseline (n=31): differences at baseline and follow-up between patients remaining severely inactive (SPI) and patients not being severely inactive (non-SPI) at follow-up (responders)

	Persistent SPI (n=24)		Responders (n=7)
	Baseline	Follow-up	Baseline	Follow-up
Physical activity level (TEE divided by RMR), median (range)	1.3 (1.2–1.3)	1.3 (1.1–1.3)a	1.3 (1.1–1.3)b	1.4 (1.4–1.5)a,b
Resting energy expenditure (J/day)	6,552 (4,464–9,768)	6,969 (4,344–8,784)	6,432 (4,872–9,768)	7,032 (4,728–10,920)
Steps, median (range)	1,758 (226–5,501)	1,683 (180–5,065)a	3,149 (112–4,755)	4,015 (1,598–5,564)a
Minutes/week at ≥3 MET, median (range)	264 (12–1,098)	276 (6–810)	348 (48–1,284)	546 (138–1,704)
No of patients with ≥3 MET in 150 minutes/week, n (%)	15 (60)	18 (75)	5 (71)	6 (86)
Minutes/week in ≥2 MET, median (range)	552 (48–2,160)	960 (114–1,860)a	1,164 (252–2,340)	1,608 (1,200–2,520)a
No of patients with ≥2 MET in 150 minutes/week, n (%)	22 (92)	23 (96)	7 (100)	7 (100)
CAT, median (range)	17 (10–32)	16 (7–29)	17 (11–28)	19 (11–34)
mMRC, median (range)	2 (1–4)	2 (0–4)	2 (1–4)	2 (1–4)
BMI, median (range)	27.9 (18.4–42.9)		27.0 (16.6–27.8)
FEV1 (% predicted), median (range)	48 (28–73)		54 (26–96)
COPD class B, n (%)	9 (38)		2 (29)

Notes:

a Intergroup difference, P<0.05.

b Intragroup difference, P<0.05. Gray box, only baseline data available.

Abbreviations: BMI, body mass index; CAT, COPD Assessment Test; MET, Metabolic Equivalent of Task; RMR, resting metabolic rate; SPI, severe physical inactivity; TEE, total energy expenditure.