Figures & data
Figure 1 Role of inflammatory cells in airway remodeling in COPD.
Notes: Exogenous oxidants cause infiltration of inflammatory cells including neutrophils, macrophages, mast cells, and lymphocytes into the airway and lung tissue, resulting in excessive expression of some proteases and inflammatory mediators. This induces the accumulation of inflammatory cells into the airway, leading to the remodeling of airway structure.
Abbreviations: ILC, innate lymphoid cell; MCP, monocyte chemoattractant protein; MMPs, matrix metalloproteinases; MPO, myeloperoxidase; NE, neutrophil elastase; TGF-β, transforming growth factor-β; TNF-α, tumor necrosis factor-α; VEGF, vascular endothelial growth factor.
Abbreviations: ILC, innate lymphoid cell; MCP, monocyte chemoattractant protein; MMPs, matrix metalloproteinases; MPO, myeloperoxidase; NE, neutrophil elastase; TGF-β, transforming growth factor-β; TNF-α, tumor necrosis factor-α; VEGF, vascular endothelial growth factor.
