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Original Research

The Relationship Between the “Adherence Starts with Knowledge-20” Questionnaire and Clinical Factors in Patients with COPD: A Multi-Center, Cross-Sectional Study

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Pages 3201-3211 | Published online: 04 Dec 2020

Figures & data

Table 1 Characteristics of the Included Studies

Figure 1 Distribution of Adherence Starts with Knowledge-20 (ASK-20) score. The median total ASK-20 score was 38 (33–44). The x-axis shows the total ASK-20 scores and the y-axis shows the frequency.

Figure 1 Distribution of Adherence Starts with Knowledge-20 (ASK-20) score. The median total ASK-20 score was 38 (33–44). The x-axis shows the total ASK-20 scores and the y-axis shows the frequency.

Table 2 Relationship Between Comorbidities and Adherence Starts with Knowledge-20 (ASK-20) Score and Total Barrier Counts (TBCs)

Figure 2 Correlation of total Adherence Starts with Knowledge-20 (ASK-20) score and total barrier counts (TBCs) with patients’ clinical factors and inhaler therapy. Correlation plot of age with ASK-20 score (A) and TBCs (B). Correlation plot of CAT score with ASK-20 score (C) and TBCs (D). Correlation plot of mMRC with ASK-20 score (E) and TBCs (F). Correlation plot of the HADS-anxiety score with the ASK-20 score (G) and TBCs (H). Correlation plot of the HADS-depression score with the ASK-20 score (I) and TBCs (J). Correlation plot of the %FEV1.0 with the ASK-20 score (K) and TBCs (L). The total ASK-20 scores and TBCs were significantly correlated with the CAT, HADS-anxiety, and HADS-depression scores.

Abbreviations: ASK-20, Adherence Starts with Knowledge-20; CAT, the COPD Assessment Test; %FEV1, % predicted forced expiratory volume in 1 second; HADS, the Hospital Anxiety and Depression Scale; mMRC, the modified Medical Research Council; TBCs, total barrier counts.
Figure 2 Correlation of total Adherence Starts with Knowledge-20 (ASK-20) score and total barrier counts (TBCs) with patients’ clinical factors and inhaler therapy. Correlation plot of age with ASK-20 score (A) and TBCs (B). Correlation plot of CAT score with ASK-20 score (C) and TBCs (D). Correlation plot of mMRC with ASK-20 score (E) and TBCs (F). Correlation plot of the HADS-anxiety score with the ASK-20 score (G) and TBCs (H). Correlation plot of the HADS-depression score with the ASK-20 score (I) and TBCs (J). Correlation plot of the %FEV1.0 with the ASK-20 score (K) and TBCs (L). The total ASK-20 scores and TBCs were significantly correlated with the CAT, HADS-anxiety, and HADS-depression scores.

Table 3 Multivariable Analysis of Factors Associated with the Adherence Starts with Knowledge-20 (ASK-20) Score

Table 4 Relationship Between Inhaler Devices and Clinical Factors

Table 5 Differences in Clinical Factors Between Patients Treated with Single or Multiple Maintenance Inhalers