The Relationship Between the “Adherence Starts with Knowledge-20” Questionnaire and Clinical Factors in Patients with COPD: A Multi-Center, Cross-Sectional Study

References

• SorianoJB, KendrickPJ, PaulsonKR; GBD Chronic Respiratory Disease Collaborators. Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Respir Med. 2020;8:585–596. doi:10.1016/S2213-2600(20)30105-332526187
   PubMed Web of Science ®Google Scholar
• DavidM. Epidemiology, prevalence, morbidity and mortality, and disease heterogeneity. Chest. 2002;121:121–126.
   Web of Science ®Google Scholar
• TerryPD, DhandR. Inhalation therapy for stable COPD: 20 years of GOLD reports. Adv Ther. 2020;37:1812–1828. doi:10.1007/s12325-020-01289-y32246264
   PubMed Web of Science ®Google Scholar
• RocheN, AguilaniuB, LiPZ, HessD; COLIBRI collaborators. Trends over time in COPD treatment choices by respiratory physicians: an analysis from the COLIBRI-COPD French cohort. Respir Med. 2019;156:8–14. doi:10.1016/j.rmed.2019.07.02331374262
   PubMed Web of Science ®Google Scholar
• AtsutaR, ToY, SakamotoS, et al. Assessing usability of the “Adherence Starts with Knowledge 20” (ASK-20) questionnaire for Japanese adults with bronchial asthma receiving inhaled corticosteroids long term. Allergol Int. 2017;66:411–417. doi:10.1016/j.alit.2016.09.00127712949
   PubMed Web of Science ®Google Scholar
• RoglianiP, OraJ, PuxedduE, MateraMG, CazzolaM. Adherence to COPD treatment: myth and reality. Respir Med. 2017;129:117–123. doi:10.1016/j.rmed.2017.06.00728732818
   PubMed Web of Science ®Google Scholar
• MäkeläMJ, BackerV, HedegaardM, LarssonK. Adherence to inhaled therapies, health outcomes and costs in patients with asthma and COPD. Respir Med. 2013;107:481–490. doi:10.1016/j.rmed.2013.04.005
   Web of Science ®Google Scholar
• PriceD, KeiningerDL, ViswanadB, GasserM, WaldaS, GutzwillerFS. Factors associated with appropriate inhaler use in patients with COPD - lessons from the REAL survey. Int J Chronic Obstruct Pulmon Dis. 2018;13:695–702. doi:10.2147/COPD.S149404
   PubMed Web of Science ®Google Scholar
• MolimardM, ColthorpeP. Inhaler devices for chronic obstructive pulmonary disease: insights from patients and healthcare practitioners. J Aerosol Med Pulm Drug Deliv. 2015;28:219–228. doi:10.1089/jamp.2014.114225265316
   PubMed Web of Science ®Google Scholar
• AhnJH, ChungJH, ShinKC, et al. Critical inhaler handling error is an independent risk factor for frequent exacerbations of chronic obstructive pulmonary disease: interim results of a single center prospective study. Int J Chron Obstruct Pulmon Dis. 2019;14:2767–2775. doi:10.2147/COPD.S23477431819409
   PubMed Web of Science ®Google Scholar
• MüllerT, MüllerA, HübelC, et al. Optimizing inhalation technique using web-based videos in obstructive lung diseases. Respir Med. 2017;129:140–144.28732821
   PubMed Web of Science ®Google Scholar
• MelaniAS, BonaviaM, CilentiV, et al. Inhaler mishandling remains common in real life and is associated with reduced disease control. Respir Med. 2011;105:930–938. doi:10.1016/j.rmed.2011.01.00521367593
   PubMed Web of Science ®Google Scholar
• Serra-BatllesJ, PlazaV, BadiolaC, MorejónE; Inhalation Devices Study Group. Patient perception and acceptability of multidose dry powder inhalers: a randomized crossover comparison of Diskus/Accuhaler with Turbuhaler. J Aerosol Med. 2002;15:59–64. doi:10.1089/0894268025290858412006146
   PubMedGoogle Scholar
• JonesC, SantanelloNC, BoccuzziSJ, WogenJ, StrubP, NelsenLM. Adherence to prescribed treatment for asthma: evidence from pharmacy benefits data. J Asthma. 2003;40:93–101. doi:10.1081/JAS-12001721212699217
   PubMed Web of Science ®Google Scholar
• RandC, BilderbackA, SchillerK, EdelmanJM, HustadCM, ZeigerRS. Adherences with montelukast or fluticasone in a long-term clinical trial: results from the mild asthma montelukast versus inhaled corticosteroid trial. J Allergy Clin Immunol. 2007;119:916–923. doi:10.1016/j.jaci.2006.12.66417349681
   PubMed Web of Science ®Google Scholar
• BroderMS, ChangEY, OryC, KamathT, SapraS. Adherence and persistence with omalizumab and fluticasone/salmeterol within a managed care population. Allergy Asthma Proc. 2009;30:148–157. doi:10.2500/aap.2009.30.319019152727
   PubMed Web of Science ®Google Scholar
• TamuraG, OhtaK. Adherence to treatment by patients with asthma or COPD: comparison between inhaled drugs and transdermal patch. Respir Med. 2007;101:1895–1902. doi:10.1016/j.rmed.2007.05.00117587559
   PubMed Web of Science ®Google Scholar
• ToyamaT, KawayamaT, KinoshitaT, et al. Differences in adherence barriers to inhaled medicines between Japanese patients with chronic obstructive pulmonary disease and asthma evaluated using the “Adherence Starts with Knowledge 20” (ASK-20) questionnaire. Intern Med. 2019;58:175–185. doi:10.2169/internalmedicine.0488-1730210101
   PubMed Web of Science ®Google Scholar
• PierobonA, Sini BottelliE, RanziniL, et al. COPD patients’ self-reported adherence, psychosocial factors and mild cognitive impairment in pulmonary rehabilitation. Int J Chron Obstruct Pulmon Dis. 2017;12:2059–2067. doi:10.2147/COPD.S13358628790808
   PubMed Web of Science ®Google Scholar
• HahnSR, ParkJ, SkinnerEP, et al. Development of the ASK-20 adherence barrier survey. Curr Med Res Opin. 2008;24:2127–2138. doi:10.1185/0300799080217476918554431
   PubMed Web of Science ®Google Scholar
• SasakiJ, KawayamaT, YoshidaM, et al. Adherence barriers to inhaled medicines in Japanese older patients with asthma evaluated using the “Adherence Starts with Knowledge 20” (ASK-20) questionnaire. J Asthma. 2019;56:632–641. doi:10.1080/02770903.2018.148413229969920
   PubMed Web of Science ®Google Scholar
• López-CamposJL, Quintana GallegoE, Carrasco HernándezL. Status of and strategies for improving adherence to COPD treatment. Int J Chron Obstruct Pulmon Dis. 2019;14:1503–1515. doi:10.2147/COPD.S17084831371936
   PubMed Web of Science ®Google Scholar
• MiravitllesM, Montero-CaballeroJ, RichardF, et al. A cross-sectional study to assess inhalation device handling and patient satisfaction in COPD. Int J Chron Obstruct Pulmon Dis. 2016;11:407–415. doi:10.2147/COPD.S9111827013871
   PubMed Web of Science ®Google Scholar
• BestallJC, PaulEA, GarrodR, GarnhamR, JonesPW, WedzichaJA. Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax. 1999;54:581–586. doi:10.1136/thx.54.7.58110377201
   PubMed Web of Science ®Google Scholar
• JonesPW, HardingG, BerryP, WiklundI, ChenWH, Kline LeidyN. Development and first validation of the COPD assessment test. Eur Respir J. 2009;34:648–654. doi:10.1183/09031936.0010250919720809
   PubMed Web of Science ®Google Scholar
• Dueñas-EspínI, DemeyerH, Gimeno-SantosE, et al. Depression symptoms reduce physical activity in COPD patients: a prospective multicenter study. Int J Chron Obstruct Pulmon Dis. 2016;11:1287–1295. doi:10.2147/COPD.S10145927354787
   PubMed Web of Science ®Google Scholar
• AndrianaI. The impact of depressive symptoms on recovery and outcome of hospitalized COPD exacerbations. Eur Respir J. 2013;41:815–823. doi:10.1183/09031936.0001311222878874
   PubMed Web of Science ®Google Scholar
• HumenbergerM, HornerA, LabekA, et al. Adherence to inhaled therapy and its impact on chronic obstructive pulmonary disease (COPD). BMC Pulm Med. 2018;18:163. doi:10.1186/s12890-018-0724-330340565
   PubMed Web of Science ®Google Scholar
• BjermerL. The importance of continuity in inhaler device choice for asthma and chronic obstructive pulmonary disease. Respiration. 2014;88:346–352. doi:10.1159/00036377125195762
   PubMed Web of Science ®Google Scholar
• van der PalenJ, CerveriI, RocheN, et al. DuoResp Spiromax adherence, satisfaction and ease of use: findings from a multi-country observational study in patients with asthma and COPD in Europe (SPRINT). J Asthma. 2019:1–9.
   Web of Science ®Google Scholar
• ChrystynH, SmallM, MilliganG, HigginsV, GilEG, EstruchJ. Impact of patients’ satisfaction with their inhalers on treatment compliance and health status in COPD. Respir Med. 2014;108:358–365. doi:10.1016/j.rmed.2013.09.02124209768
   PubMed Web of Science ®Google Scholar
• PlazaV, GinerJ, CurtoE, et al. Determinants and differences in satisfaction with the inhaler among patients with asthma or COPD. J Allergy Clin Immunol Pract. 2020;8:645–653. doi:10.1016/j.jaip.2019.09.02031586668
   PubMed Web of Science ®Google Scholar
• IngebrigtsenTS, MarottJL, NordestgaardBG, et al. Low use and adherence to maintenance medication in chronic obstructive pulmonary disease in the general population. J Gen Intern Med. 2015;30:51–59. doi:10.1007/s11606-014-3029-025245885
   PubMed Web of Science ®Google Scholar
• RieN, KeikoN, AmeliaT, et al. Barriers to medication adherence among patients with non-communicable diseases: Fijian health professionals’ perceptions. J Int Health. 2014;29(4):313–320.
   Google Scholar
• StewartRB, CaranasosGJ. Medication compliance in the elderly. Med Clin North Am. 1989;73(6):1551–1563. doi:10.1016/S0025-7125(16)30616-22682077
   PubMed Web of Science ®Google Scholar
• VestboJ, AndersonJA, CalverlyPMA, et al. Adherence to inhaled therapy, mortality and hospital admission in COPD. Thorax. 2009;64(11):939–943. doi:10.1136/thx.2009.11366219703830
   PubMed Web of Science ®Google Scholar
• DavisJR, WuB, KernDM, et al. Impact of nonadherence to inhaled corticosteroid/LABA therapy on COPD exacerbation rates and healthcare costs in a commercially insured US population. Am Health Drug Benefits. 2017;10(2):92–102.28626506
   PubMed Web of Science ®Google Scholar
• IshiiT, NishimuraM, AkimotoA, JamesMH, JonesP. Understanding low COPD exacerbation rates in Japan: a review and comparison with other countries. Int J Chron Obstruct Pulmon Dis. 2018;13:3459–3471. doi:10.2147/COPD.S16518730464435
   PubMed Web of Science ®Google Scholar
• DarbàJ, RamírezR, SicrasA, et al. The importance of inhaler devices: the choice of inhaler device may lead to suboptimal adherence in COPD patients. Int J Chron Obstruct Pulmon Dis. 2015;10:2335–2345. doi:10.2147/COPD.S9015526604733
   PubMed Web of Science ®Google Scholar
• QianJ, Simoni-WastilaL, RattingerGB, et al. Association between depression and maintenance medication adherence among Medicare beneficiaries with chronic obstructive pulmonary disease. Int J Geriatr Psychiatry. 2014;29(1):49–57. doi:10.1002/gps.396823606418
   PubMed Web of Science ®Google Scholar
• RolnickSJ, PawloskiPA, HedblomBD, et al. Patient characteristics associated with medication adherence. Clin Med Res. 2013;11:54–65. doi:10.3121/cmr.2013.111323580788
   PubMedGoogle Scholar
• ZhouY, ZhongNS, LiX, et al. Tiotropium in early-stage chronic obstructive pulmonary disease. N Engl J Med. 2017;377:923–935. doi:10.1056/NEJMoa170022828877027
   PubMed Web of Science ®Google Scholar
• FujimotoK, YoshiikeF, YasuoM, et al. Effects of bronchodilators on dynamic hyperinflation following hyperventilation in patients with COPD. Respirology. 2007;12:93–99. doi:10.1111/j.1440-1843.2006.00963.x17207032
   PubMed Web of Science ®Google Scholar
• O’DonnellDE, WebbKA. Exercise testing In: CelliBR, editor. Pharmacotherapy in Chronic Obstructive Pulmonary Disease. New York: Marcel Dekker; 2004:45–71.
   Google Scholar
• O’DonnellDE, HernandezP, KaplanA, et al. Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease—2008 update—highlights for primary care. Can Respir J. 2008;15(SupplA):1A–8A.
   PubMedGoogle Scholar
• PauwelsRA, BuistAS, CalverleyPM, et al.; for GOLD Scientific Committee. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. Am J Respir Crit Care Med.2018;163:1256–1276. doi:10.1164/ajrccm.163.5.2101039
   Google Scholar
• BloomCI, ElkinSL, QuintJK. Changes in COPD inhaler prescriptions in the United Kingdom, 2000 to 2016. Int J Chron Obstruct Pulmon Dis. 2019;14:279–287. doi:10.2147/COPD.S19008630774325
   PubMed Web of Science ®Google Scholar
• YuAP, GuérinA, Ponce de LeonD, et al. Therapy persistence and adherence in patients with chronic obstructive pulmonary disease: multiple versus single long-acting maintenance inhalers. J Med Econ. 2011;14:486–496. doi:10.3111/13696998.2011.59412321679019
   PubMedGoogle Scholar
• van der PalenJ, KleinJJ, van HerwaardenCL, ZielhuisGA, SeydelER. Multiple inhalers confuse asthma patients. Eur Respir J. 1999;14:1034–1037. doi:10.1183/09031936.99.1451034910596686
   PubMed Web of Science ®Google Scholar
• TøttenborgSS, LangeP, JohnsenSP, NielsenH, IngebrigtsenTS, ThomsenRW. Socioeconomic inequalities in adherence to inhaled maintenance medications and clinical prognosis of COPD. Respir Med. 2016;119:160–167. doi:10.1016/j.rmed.2016.09.00727692139
   PubMed Web of Science ®Google Scholar