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Original Research

A comparison of synchronized intermittent mandatory ventilation and pressure-regulated volume control ventilation in elderly patients with acute exacerbations of COPD and respiratory failure

, , , &
Pages 1023-1029 | Published online: 17 May 2016

Figures & data

Table 1 Comparisons between the two groups in sex, age, respiratory rate, and arterial blood gas analysis indexes before treatment

Figure 1 Study flow and randomization of patients to the intervention and control groups.

Abbreviations: PaO2, partial pressure of oxygen in arterial blood; PaCO2, partial pressure of carbon dioxide in arterial blood; PRVC, pressure-regulated volume control; SIMV, synchronized intermittent mandatory ventilation; h, hours.
Figure 1 Study flow and randomization of patients to the intervention and control groups.

Table 2 The vital signs, blood gas analysis, and indexes of breathing mechanics 2–4 hours and 48 hours after treatment in the two groups

Figure 2 Changes in pH over time (2–4 h and 48 h) in the intervention and control groups.

Notes: The black bar represents the intervention group, and the gray bar represents the control group. *P<0.05.

Abbreviations: pH, hydrogen ion concentration; h, hours; PRVC, pressure-regulated volume control; SIMV, synchronized intermittent mandatory ventilation.

Figure 2 Changes in pH over time (2–4 h and 48 h) in the intervention and control groups.Notes: The black bar represents the intervention group, and the gray bar represents the control group. *P<0.05.Abbreviations: pH, hydrogen ion concentration; h, hours; PRVC, pressure-regulated volume control; SIMV, synchronized intermittent mandatory ventilation.

Figure 3 Changes in PaCO2 (mmHg) over time (2–4 h and 48 h) in the intervention and control groups.

Notes: The black bar represents the intervention group, and the gray bar represents the control group. *P<0.05.

Abbreviations: PaCO2, partial pressure of carbon dioxide in arterial blood; h, hours; PRVC, pressure-regulated volume control; SIMV, synchronized intermittent mandatory ventilation.

Figure 3 Changes in PaCO2 (mmHg) over time (2–4 h and 48 h) in the intervention and control groups.Notes: The black bar represents the intervention group, and the gray bar represents the control group. *P<0.05.Abbreviations: PaCO2, partial pressure of carbon dioxide in arterial blood; h, hours; PRVC, pressure-regulated volume control; SIMV, synchronized intermittent mandatory ventilation.

Figure 4 Changes in PIP (cmH2O) over time (2–4 h and 48 h) in the intervention and control arms.

Notes: The black bar represents the intervention group, and the gray bar represents the control group. *P<0.05.
Abbreviations: PIP, peak inspiratory pressure; h, hours; PRVC, pressure-regulated volume control; SIMV, synchronized intermittent mandatory ventilation.
Figure 4 Changes in PIP (cmH2O) over time (2–4 h and 48 h) in the intervention and control arms.