Figures & data
Table 1 Relationship between the commonest genotypes and AAT serum concentration
Table 2 Purified AAT products currently licensed for intravenous administration
Table 3 Summary of studies to assess efficacy of AAT augmentation therapy
Figure 1 Voxel frequency distribution histogram showing the appearance of normal lung (black line) and emphysema (gray line) and the derivation of the commonest densitometric indices.
Abbreviation: HU, Hounsfield unit.
![Figure 1 Voxel frequency distribution histogram showing the appearance of normal lung (black line) and emphysema (gray line) and the derivation of the commonest densitometric indices.](/cms/asset/784a8fcd-9fee-4997-9991-cf0f11611bb4/dddt_a_105207_f0001_c.jpg)
Figure 2 Change from baseline in 15th percentile lung density (PD15), over the course of the RAPID study (RAPID-RCT and RAPID-OLE).
Abbreviations: ITT, intention to treat; TLC, total lung capacity; RCT, randomized controlled trial; OLE, open-label extension.
![Figure 2 Change from baseline in 15th percentile lung density (PD15), over the course of the RAPID study (RAPID-RCT and RAPID-OLE).](/cms/asset/49b79e5d-16b1-49da-b74a-0daec7e4b0e3/dddt_a_105207_f0002_c.jpg)
Table 4 Summary of key points from different AATD guidelines