https://orcid.org/0000-0003-4226-1834
Figures & data
Figure 1 Chemical structure of PTL and DMAPT.
Table 1 Pharmacological Activities of PTL in Tumors (Since 2019)
Figure 2 Selected signaling pathways regulated by PTL. The key components and signal transduction cascade reactions in NF-κB signaling, Wnt/β-catenin signaling, JAK/STAT signaling, FAK1 signaling, and p53 signaling were depicted, and the nodes targeted by PTL were labeled.
Notes: ㊀ Represents the inhibitory effect, and ㊉ Represents the activation effect.
Figure 3 Pivotal cellular processes affected by PTL. Schematic diagram showing the formation of microtentacle and major antioxidant machineries were plotted. The targets regulated by PTL were marked.
Note: ↑ Represents the accumulation of ROS.
Table 2 Unmodified Nanoparticles Solely Incorporated with PTL
Table 3 Undecorated Nanovectors Encapsulated PTL and Other Agents
Table 4 Targeted Nanocarriers Encapsulated PTL with or without Other Agents
Figure 4 Chemical structure of MCL, MMB and COS.
