Figures & data
Figure 1 Mutagenic deamination of DNA methylation.
Notes: This process started originally with an epigenetic change of cytosine during methylation, but a resultant deamination of an intermediate product (5-methyl cytosine) made it a complicated situation beyond epigenetics, to a possible SNP. This is therefore not strictly an epigenetic change, notwithstanding that it started like usual DNA methylation.
Abbreviation: SNP, single nucleotide polymorphism.
Abbreviation: SNP, single nucleotide polymorphism.
Figure 2 Nucleosome and component histones.
Notes: The octamer histone core (H2A, H2B, H3, and H4) is wrapped by the DNA and locked on the outside by H1 histone.
Figure 3 Chemical structures of major histone modifications.
Notes: The chemical structure represents the histone marks for some lysine and arginine amino acid modifications. They are formed by covalent addition of either acetyl or methyl groups or their multiples.
Figure 4 The cis and trans isomers of proline.
Notes: The process of the formation of trans and cis conformation is via isomerism, and the reaction is a reversible process.
