Effects of Xuanbai Chengqi decoction on lung compliance for patients with exogenous pulmonary acute respiratory distress syndrome

Figures & data

Table 1 Comparisons of blood gas analysis, respiratory mechanics parameters, and pathogenesis of patients enrolled in the two groups (mean ± standard deviation)

Items	Treatment group (n=25)	Control group (n=28)
Age (years)	60.5±14.6	58.8±16.8
APACHE II score	18.8±4.8	19.2±4.2
PaO2/FiO2	148±47	150±8
Vt (mL/kg)	6.9±0.6	6.6±1.3
Plateau pressure (cm H2O)	27.61±4.5	26.63±5.7
Peak airway pressure (cm H2O)	37.62±6.5	36.53±7.4
PEEP (cm H2O)	12.6±3.7	12.5±3.5

Abbreviations: APACHE II, acute physiology and chronic health evaluation II; FiO₂, fraction of inspired O₂; PaO₂, arterial oxygen pressure; PEEP, positive end-expiratory pressure; Vt, tidal volume.

Table 2 Comparisons of relevant indexes of mechanical ventilation for patients in two groups before and after treatment (mean ± standard deviation)

Groups	Time	Cases	Static lung compliance (mL/cm H2O)	Dynamic lung compliance (mL/cm H2O)	Plateau pressure (mmHg)	Peak airway pressure (mmHg)	PEEP (cm H2O)
Treatment group	Before treatment	25	23.46±6.5	22.71±5.7	26.61±4.5	35.62±6.5	10.6±3.7
	24 h after treatment	25	25.29±4.7	24.53±4.5	23.18±5.4**	33.58±5.1	8.7±3.6
	48 h after treatment	25	29.66±6.3*	28.87±5.1*	21.89±4.3**	30.47±5.4**	6.8±3.1**
	72 h after treatment	25	32.71±5.8*	31.36±4.2*	20.69±4.9**	28.78±5.0**	4.5±2.3*
Control group	Before treatment	28	22.87±7.1	22.82±4.8	25.83±5.7	34.53±7.4	10.5±3.5
	24 h after treatment	28	24.18±5.2	23.68±5.1	24.64±4.6	33.82±4.3	8.9±3.2
	48 h after treatment	28	26.29±5.1	25.14±5.2	23.49±4.8	32.71±5.0	7.8±2.7
	72 h after treatment	28	28.38±4.8**	26.41±3.6	22.82±4.1**	31.66±3.6	7.1±2.1

Notes: Comparing the same time points in the control group,

* P<0.05; comparing with the same group before treatment,

** P<0.05.

Abbreviations: PEEP, positive end-expiratory pressure; h, hours.

Table 3 Comparisons of the days of abdominal distension and parenteral nutrition for patients in the two groups (mean ± standard deviation)

Groups	Cases	Parenteral nutrition, days
Treatment group	25	2.2±1.2*
Control group	28	4.3±2.1

Note: Comparing with the control group,

* P<0.05.

Table 4 Comparisons of mechanical ventilation complication and fatality for patients in the two groups (cases [%])

Groups	Cases	Abdominal distension	Ventilator-associated pneumonia	Fatality in 28 days
Treatment group	25	3 (12)*	8 (32)*	5 (20)*
Control group	28	19 (67.8)	16 (57.1)	12 (42.8)

Note: Comparing with the control group,

* P<0.05.