Advanced search
Publication Cover
Drug Design, Development and Therapy Volume 10, 2016 - Issue
Submit an article Journal homepage
60
Views
8
CrossRef citations to date
0
Altmetric
Original Research

Long-term use of amiodarone before heart transplantation significantly reduces early post-transplant atrial fibrillation and is not associated with increased mortality after heart transplantation

Rasmus Rivinius1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Matthias Helmschrott1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Arjang Ruhparwar2 Department of Cardiac Surgery, Heidelberg University Hospital, Heidelberg, Germany
,
Bastian Schmack2 Department of Cardiac Surgery, Heidelberg University Hospital, Heidelberg, Germany
,
Christian Erbel1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Christian A Gleissner1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Mohammadreza Akhavanpoor1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Lutz Frankenstein1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Fabrice F Darche1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Patrick A Schweizer1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Dierk Thomas1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Philipp Ehlermann1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
,
Tom Bruckner3 Institute for Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany
,
Hugo A Katus1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, Germany
&
Andreas O Doesch1 Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Heidelberg, GermanyCorrespondence[email protected]
 show all
Pages 677-686 | Published online: 16 Feb 2016

Figures & data

Table 1 Patient characteristics

Figure 1 Indications for pre-transplant use of amiodarone.

Notes: Indications for long-term amiodarone therapy were atrial fibrillation in ten patients (13.5%), Wolff–Parkinson–White syndrome in one patient (1.4%), ventricular tachycardia in 57 patients (77.0%), and ventricular fibrillation in six patients (8.1%).
Figure 1 Indications for pre-transplant use of amiodarone.

Table 2 Initial post-transplant medication

Table 3 Influence of long-term use of amiodarone on early post-transplant atrial fibrillation

Figure 2 Kaplan–Meier estimator (freedom from early post-transplant atrial fibrillation).

Note: Freedom from early post-transplant atrial fibrillation (≤30 days after HTX) in patients with/without pre-transplant use of amiodarone.
Abbreviations: HTX, heart transplantation; AF, atrial fibrillation.
Figure 2 Kaplan–Meier estimator (freedom from early post-transplant atrial fibrillation).

Table 4 Influence of long-term use of amiodarone on mortality after HTX

Figure 3 Kaplan–Meier estimator (overall follow-up survival).

Note: Survival of patients with/without pre-transplant use of amiodarone.
Abbreviation: HTX, heart transplantation.
Figure 3 Kaplan–Meier estimator (overall follow-up survival).

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.