109
Views
6
CrossRef citations to date
0
Altmetric
Original Research

Development of a liposome-based formulation for vitamin K1 nebulization on the skin

, , , , &
Pages 1823-1832 | Published online: 10 Apr 2014

Figures & data

Table 1 Characteristics of the liposomal formulations

Table 2 Stability of the liposomal formulations

Table 3 Visual and organoleptic analysis of the formulation LVB stored in different conditions

Table 4 Characteristics of the formulation LVB

Figure 1 Chromatogram of sample extracted by LVB following storage under light.

Note: The peak with the retention time of 7.3 minutes was attributed to native vitamin K1.

Figure 1 Chromatogram of sample extracted by LVB following storage under light.Note: The peak with the retention time of 7.3 minutes was attributed to native vitamin K1.

Table 5 Characteristics of the formulation LVB-TOC-BC

Table 6 Visual and organoleptic analysis of the formulation LVB-TOC-BC stored in different conditions

Table 7 Characterization of the formulation LVB-TOC-BC

Table 8 Mean diameter and polydispersity index before and after nebulization of the formulation LVB-TOC-BC

Figure 2 Nebulization of the formulation LVB-TOC-BC by the portable device Eauté.

Figure 2 Nebulization of the formulation LVB-TOC-BC by the portable device Eauté.

Figure 3 Accumulation of VK1 in epidermis (A) and dermis (B).

Abbreviations: NEB, nebulization; VK1, vitamin K1; conc, concentration.

Figure 3 Accumulation of VK1 in epidermis (A) and dermis (B).Abbreviations: NEB, nebulization; VK1, vitamin K1; conc, concentration.