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EXPERT OPINION

Treatment Patterns and Recommendations for Improving the Management of Hepatocellular Carcinoma in Saudi Arabia

, , , , , , , , , & ORCID Icon show all
Pages 349-362 | Received 01 Nov 2023, Accepted 17 Jan 2024, Published online: 16 Feb 2024

Figures & data

Figure 1 Distribution of risk factors and stages of HCC. (A) Distribution of risk factors for HCC. (B) Distribution of the different stages of HCC as per BCLC classification.

Abbreviations: BCLC, Barcelona Clinic Liver Cancer; HCC, hepatocellular carcinoma; NAFLD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis.
Figure 1 Distribution of risk factors and stages of HCC. (A) Distribution of risk factors for HCC. (B) Distribution of the different stages of HCC as per BCLC classification.

Figure 2 Algorithm for HCC diagnosis.

Notes: Adapted from Alqahtani S, Sanai F, Alolayan A, et al. Saudi Association for the Study of Liver diseases and Transplantation practice guidelines on the diagnosis and management of hepatocellular carcinoma. Saudi J Gastroenterol. 2020;26(7):1. Creative Commons.Citation7
Abbreviations: APHE, arterial phase hyperenhancement; CT, computed tomography; HCC, hepatocellular carcinoma; MRI, magnetic resonance imaging; USG, ultrasonography.
Figure 2 Algorithm for HCC diagnosis.

Figure 3 Commonly used locoregional treatments for HCC in Saudi Arabia.

Abbreviations: HCC, hepatocellular carcinoma; MWA, microwave ablation; PEA, percutaneous ethanol ablation; RFA, radiofrequency ablation; TACE, transarterial chemoembolization; TARE, transarterial radioembolization.
Figure 3 Commonly used locoregional treatments for HCC in Saudi Arabia.

Figure 4 Factors to be considered when evaluating patients for TACE.

Abbreviations: AFP, alfa-fetoprotein; ALBI, albumin-bilirubin; ECOG, Eastern Cooperative Oncology Group; TACE, transarterial chemoembolization.
Figure 4 Factors to be considered when evaluating patients for TACE.

Figure 5 Eligibility criteria for systemic therapy. (A) Percentage of patients eligible for systemic therapy. (B) Majority of experts prescribed immunotherapies mostly in first-line setting (C) Percentage of patients prescribed with sorafenib.

Abbreviations: BCLC, Barcelona Clinic Liver Cancer; HCC, hepatocellular carcinoma; TACE, transarterial chemoembolization.
Figure 5 Eligibility criteria for systemic therapy. (A) Percentage of patients eligible for systemic therapy. (B) Majority of experts prescribed immunotherapies mostly in first-line setting (C) Percentage of patients prescribed with sorafenib.