Indeterminate Colitis – Update on Treatment Options

Figures & data

Table 1 Different Classes of Medical Treatment for Indeterminate Colitis

Therapy	Strength of Evidence	First Line: Yes/No	Risk of Side Effects: Low, Intermediate, High	Disease Severity
Anti-TNF-alpha agents	Inadequate	No	Intermediate	Severe and refractory
Thiopurines: azathioprine/6-MP	Inadequate	No	Intermediate	Moderate
Steroids	Moderate	No	High	Moderate to severe
Vedolizumab	Inadequate	Unknown	Low	Unknown
Ustekinumab	Inadequate	Unknown	Low	Unknown
Mesalamines	Moderate	Yes	Low	Mild

Notes: We reviewed all available literature using the following databases: PubMed, Medscape, and UpToDate. Owing to the scarce data, IC has been looked at as a subgroup in larger IBD studies.