Figures & data
Figure 1 Nitric oxide scavenging activity of REVERC3 and regular turmeric extract. Values are expressed as mean ± SEM of three experiments.
Figure 2 Dose-dependent inhibitory effects of REVERC3 and regular turmeric extract on xanthine oxidase (A) and Lipoxygenase (B). The results were expressed as mean ± SEM of three experiments.
Figure 3 Effect of REVERC3 and regular turmenric extract on cell viability of RAW 264.7 macrophages and NO levels. Cell viability was assessed by MTT method, and the results were expressed as percentage of surviving cells over control (A) and NO production level in LPS-stimulated RAW 264.7 macrophages (B).
Figure 4 Effect of REVERC3 and regular turmeric extract on cytokine production in LPS-stimulated RAW 264.7 macrophages. RAW264.7 cells were co-treated with REVER3C (10 and 20 µg/mL) and LPS (1 μg/mL) for 24 h. Levels of (A) TNF-α and (B) IL-6 in culture supernatants were measured by ELISA. The data presented are the mean ± SEM. *** p < 0.0001 vs the control group ***p < 0.0001 vs the LPS group.
Figure 5 Effect of REVERC3 and regular curcumin on the protein expression of iNOS, COX-2 and NFkB- α in LPS stimulated RAW264.7 cells. Total proteins were isolated and analyzed by Western blot.
Table 1 Effect of REVERC3 on Carrageenan-Induced Paw Edema in Rats