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Original Research

Study of the Expression of Inflammatory Factors IL-4, IL-6, IL-10, and IL-17 in Liver Failure Complicated by Coagulation Dysfunction and Sepsis

, , , , , , , & show all
Pages 1447-1453 | Published online: 15 Apr 2021

Figures & data

Figure 1 (A) The standard curve of IL-4 detected in the plasma. (B) The standard curve of IL-6 detected in the plasma. (C) The standard curve of IL-10 detected in the plasma. (D) The standard curve of IL-17 detected in the plasma.

Figure 1 (A) The standard curve of IL-4 detected in the plasma. (B) The standard curve of IL-6 detected in the plasma. (C) The standard curve of IL-10 detected in the plasma. (D) The standard curve of IL-17 detected in the plasma.

Figure 2 The comparison of the levels of cytokines IL4, IL6, IL10, and IL17 in the control group, the liver failure group, and the liver failure combined with sepsis group. (A) The level of IL-4 not significantly different between the control group, the liver failure group, and the liver failure combined with sepsis group (P>0.05). (B) The level of IL-6 was highly increased in ACLF-SP than in ACLF group and LC group (**P<0.01, compared with ACLF and LC group, respectively), and the level of IL-6 was highly increased in ACLF group than LC group (**P<0.01, compared with LC group). (C) The level of IL-10 was obviously increased in ACLF-SP than in ACLF group and LC group (**P<0.01 compared with ACLF and LC group, respectively), and the level of IL-10 was highly increased in ACLF group than LC group (**P<0.01, compared with LC group). (D) The level of IL-17 was significantly increased in ACLF-SP than in ACLF group and LC group (**P<0.01 compared with ACLF and LC group, respectively), and the level of IL-17 was highly increased in ACLF group than LC group (**P<0.01, compared with LC group).

Figure 2 The comparison of the levels of cytokines IL4, IL6, IL10, and IL17 in the control group, the liver failure group, and the liver failure combined with sepsis group. (A) The level of IL-4 not significantly different between the control group, the liver failure group, and the liver failure combined with sepsis group (P>0.05). (B) The level of IL-6 was highly increased in ACLF-SP than in ACLF group and LC group (**P<0.01, compared with ACLF and LC group, respectively), and the level of IL-6 was highly increased in ACLF group than LC group (**P<0.01, compared with LC group). (C) The level of IL-10 was obviously increased in ACLF-SP than in ACLF group and LC group (**P<0.01 compared with ACLF and LC group, respectively), and the level of IL-10 was highly increased in ACLF group than LC group (**P<0.01, compared with LC group). (D) The level of IL-17 was significantly increased in ACLF-SP than in ACLF group and LC group (**P<0.01 compared with ACLF and LC group, respectively), and the level of IL-17 was highly increased in ACLF group than LC group (**P<0.01, compared with LC group).