Inverse Association Between Helicobacter pylori Infection and Unexplained Isolated Terminal Ileitis: A Retrospective Study

Figures & data

Table 1 Characteristics of Study Subjects

Clinicopathological Variables		Total	H. pylori	H. pylori	P value
			Negative (n=739)	Positive (n=247)
Age		46.91±11.969	40.8±12.820	47.47±11.818	0.137
	<60	842(85.40%)	624(74.11%)	218(25.89%)	0.141
	≥60	144(14.60%)	115(79.86%)	29(20.14%)
Gender					0.268
	Female	457(46.35%)	335(73.30%)	122(26.70%)
	Male	529(53.65%)	404(76.37%)	125(23.63%)
Presenting symptoms					0.089
	Abdominal pain	238(24.14%)	179(75.21%)	59(24.79%)
	Vomiting/nausea	95(9.63%)	69(72.63%)	26(27.37%)
	Diarrhea	167(16.94%)	114(68.26%)	53(31.74%)
	Dyspepsia	84(8.52%)	60(71.43%)	24(28.57%)
	None	402(40.77%)	317(78.86%)	85(21.14%)

Figure 1 The flow diagram of selection of the subjects in the study.

Table 2 Correlation Between H. pylori Infection and UITI in the Study

Factor	H. pylori	H. pylori	Adjust
	Negative (n=739)	Positive (n=247)	OR (95% CI)	P value
Non-ileitis(n=901)	667(90.26%)	234(94.74%)	0.518 (0.281–0.956)	0.035*
Ileitis(n=85)	72(9.74%)	13(5.26%)

Note: *P<0.05.

Table 3 Correlation Between H. pylori Infection and UITI in Subgroups of Our Study

Subgroups		Ileitis	H. pylori Negative (n=739)	H. pylori Positive (n=247)	Adjust
					OR (95% CI)	P value
Age	<60	Non-ileitis (n=766)	560	206	0.521 (0.275–0.987)	0.046*
		Ileitis (n=76)	64	12
	≥60	Non-ileitis (n=135)	107	28	0.476 (0.057–3.981)	0.494
		Ileitis (n=9)	8	1
Gender	Female	Non-ileitis (n=430)	313	117	0.609 (0.225–1.647)	0.329
		ileitis (n=27)	22	5
	Male	Non-ileitis (n=471)	354	117	0.471 (0.217–1.025)	0.058
		Ileitis (n=58)	50	8

Note: *P<0.05.