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Clinical Ophthalmology Volume 12, 2018 - Issue
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Review

Combination of hyaluronic acid, carmellose, and osmoprotectants for the treatment of dry eye disease

Antonio José Mateo Orobia1 Cornea and Ocular Surface Unit, Aragón Healthcare Research Institute (Instituto de Investigación Sanitaria de Aragón), Miguel Servet University Hospital, Zaragoza, SpainCorrespondence[email protected]
,
Jorge Saa2 Ophthalmology Department and Research Unit of Jove Hospital Foundation, Gijón, Spain
,
Alberto Ollero Lorenzo3 Cornea and Ocular Surface Unit, Meixoeiro Hospital, Complejo Hospitalario Universitario de Vigo (CHUVI), Vigo, Spain
&
José María Herreras4 Valladolid University Clinical Hospital, Valladolid, Spain;5 University Institute of Applied Ophthalmobiology (IOBA [Instituto Universitario de Oftalmobiología Aplicada]). Miguel Delibes Campus, Paseo de Belén, Valladolid, Spain
Pages 453-461 | Published online: 06 Mar 2018

Figures & data

Figure 1 Mechanism of action of the different components of the fixed combined formulation of HA, CMC, and osmoprotectants (Optava Fusion®; Allergan, Inc., Irvine, CA, USA).

Abbreviations: CMC, carboxymethyl cellulose; HA, hyaluronic acid; MMP, matrix metalloproteinases.
Figure 1 Mechanism of action of the different components of the fixed combined formulation of HA, CMC, and osmoprotectants (Optava Fusion®; Allergan, Inc., Irvine, CA, USA).

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