Figures & data
Table 1 Demographics of patients involved in the study
Figure 1 Interval changes in (A) macular thickness, and (B) mean perfused ratio at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. P-value: control group differences between baseline and follow-up measurements, paired t-test. P’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.
![Figure 1 Interval changes in (A) macular thickness, and (B) mean perfused ratio at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. P-value: control group differences between baseline and follow-up measurements, paired t-test. P’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.](/cms/asset/b5f44221-89de-4f59-97a7-2f3e91520989/doph_a_12176384_f0001_b.jpg)
Figure 2 Interval changes in cup volume measured on optical coherence tomography (OCT) at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. P-value: control group differences between baseline and follow-up measurements, paired t-test. P’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.
![Figure 2 Interval changes in cup volume measured on optical coherence tomography (OCT) at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. P-value: control group differences between baseline and follow-up measurements, paired t-test. P’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.](/cms/asset/0685eefc-896c-40a4-9553-52b3f7534222/doph_a_12176384_f0002_b.jpg)
Figure 3 Interval changes in vertical cup/disk ratio measured on optical coherence tomography (OCT) at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. P-value: control group differences between baseline and follow-up measurements, paired t-test. P’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.
![Figure 3 Interval changes in vertical cup/disk ratio measured on optical coherence tomography (OCT) at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. P-value: control group differences between baseline and follow-up measurements, paired t-test. P’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.](/cms/asset/d911a0f1-0cdd-4cda-9a44-158083b7fc2e/doph_a_12176384_f0003_b.jpg)
Figure 4 Interval changes in vertical cup/disk ratio measured on optical coherence tomography at baseline, 6, 12, and 24 months in participants receiving less than ten injections and ten or more injections. P-value: differences between baseline and follow-up measurements of participants receiving less than ten injections, paired t-test. P’-value: differences between baseline and follow-up measurements of participants receiving ten or more injections, paired t-test.
![Figure 4 Interval changes in vertical cup/disk ratio measured on optical coherence tomography at baseline, 6, 12, and 24 months in participants receiving less than ten injections and ten or more injections. P-value: differences between baseline and follow-up measurements of participants receiving less than ten injections, paired t-test. P’-value: differences between baseline and follow-up measurements of participants receiving ten or more injections, paired t-test.](/cms/asset/8fc44554-9dab-43cf-be45-7b4a6d588401/doph_a_12176384_f0004_b.jpg)
Figure 5 Interval changes in vertical cup/disk ratio measured by two masked glaucoma specialists using stereo-photographs at baseline, 6, 12, and 24 months in the (A) anti-VEGF group and the (B) control group. P-value: grader 1 differences between baseline and follow-up measurements, paired t-test. P’-value: grader 2 differences between baseline and follow-up measurements, paired t-test.
![Figure 5 Interval changes in vertical cup/disk ratio measured by two masked glaucoma specialists using stereo-photographs at baseline, 6, 12, and 24 months in the (A) anti-VEGF group and the (B) control group. P-value: grader 1 differences between baseline and follow-up measurements, paired t-test. P’-value: grader 2 differences between baseline and follow-up measurements, paired t-test.](/cms/asset/4f5bb5b2-10a7-4a74-92ea-bd4b4f12c808/doph_a_12176384_f0005_b.jpg)
Figure 6 Interval changes in mean deviation measured on the (A) Humphrey Visual Field Analyzer and (B) visual acuity at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. p-value: control group differences between baseline and follow-up measurements, paired t-test. p’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.
![Figure 6 Interval changes in mean deviation measured on the (A) Humphrey Visual Field Analyzer and (B) visual acuity at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. p-value: control group differences between baseline and follow-up measurements, paired t-test. p’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.](/cms/asset/7da6a9b0-3100-4bc2-91af-b1c9fa65dfc2/doph_a_12176384_f0006_b.jpg)
Figure 7 Interval changes in intraocular pressure at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. P-value: control group differences between baseline and follow-up measurements, paired t-test. P’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.
![Figure 7 Interval changes in intraocular pressure at baseline, 6, 12, and 24 months in the control and anti-VEGF groups. P-value: control group differences between baseline and follow-up measurements, paired t-test. P’-value: anti-VEGF group differences between baseline and follow-up measurements, paired t-test.](/cms/asset/f9ba7937-e07d-4e87-b1ae-da1a924284d1/doph_a_12176384_f0007_b.jpg)