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OncoTargets and Therapy Volume 14, 2021 - Issue
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Review

Dihydroartemisinin as a Sensitizing Agent in Cancer Therapies

Qingrong Li1 Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;2 Translational Medicine Research Center, North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;3 Department of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-4835-2219View further author information
ORCID Icon,
Qiang Ma1 Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;2 Translational Medicine Research Center, North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;3 Department of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000, People’s Republic of ChinaView further author information
,
Jibing Cheng1 Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;2 Translational Medicine Research Center, North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;3 Department of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000, People’s Republic of ChinaView further author information
,
Xi Zhou1 Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;2 Translational Medicine Research Center, North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;3 Department of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000, People’s Republic of ChinaView further author information
,
Wenjie Pu1 Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;2 Translational Medicine Research Center, North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;3 Department of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000, People’s Republic of ChinaView further author information
,
Xiaowu Zhong1 Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;2 Translational Medicine Research Center, North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;3 Department of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000, People’s Republic of ChinaView further author information
&
Xiaolan Guo1 Department of Clinical Laboratory, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;2 Translational Medicine Research Center, North Sichuan Medical College, Nanchong, 637000, People’s Republic of China;3 Department of Laboratory Medicine, North Sichuan Medical College, Nanchong, 637000, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2948-8997View further author information
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Pages 2563-2573 | Published online: 13 Apr 2021

Figures & data

Figure 1 Sensitization of DHA to chemotherapy drugs. Red arrows ↑ and ↓ indicate proteins or pathways up-regulated and down-regulated by DHA to elevate the toxicity of other chemotherapy drugs to cancer cells.

Figure 1 Sensitization of DHA to chemotherapy drugs. Red arrows ↑ and ↓ indicate proteins or pathways up-regulated and down-regulated by DHA to elevate the toxicity of other chemotherapy drugs to cancer cells.

Figure 2 Sensitization of DHA to targeted drugs and radiotherapy. Red arrows ↑ and ↓ indicate proteins or pathways up-regulated and down-regulated by DHA to elevate the toxicity of targeting drugs or radiotherapy to cancer cells.

Figure 2 Sensitization of DHA to targeted drugs and radiotherapy. Red arrows ↑ and ↓ indicate proteins or pathways up-regulated and down-regulated by DHA to elevate the toxicity of targeting drugs or radiotherapy to cancer cells.

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